Results 21 to 30 of about 1,246,147 (266)

Unveiling TNFAIP8L2-related immune evasion mechanisms in colorectal cancer [PDF]

Colorectal cancer (CRC) remains to be a leading cause of cancer-related mortality worldwide. Although immune evasion appears to play a critical role in CRC progression, the underlying mechanisms are poorly defined, necessitating further scientific ...
Li, P., Mauki, D. H., Babarinde. I. A., Chen, Y. H., Kong, Y., Samuel, O., Xia, H., Lang, S.   +7 more
core   +1 more source

Immune evasion during varicella zoster virus infection of keratinocytes

, 2009
Summary T cells are sensitized during varicella-zoster virus (VZV) infection and are important for control of viral spread and reactivation.
Malavige, G.N., Jones, L., Ogg, G.S., Black, A.P.   +3 more
core   +1 more source

Immune subtypes and neoantigen-related immune evasion in advanced colorectal cancer

iScience, 2022
Summary: Elimination of cancerous cells by the immune system is an important mechanism of protection from cancer, however, its effectiveness can be reduced owing to development of resistance and evasion.
Toshitaka Sugawara, Fuyuki Miya, Toshiaki Ishikawa, Artem Lysenko, Jo Nishino, Takashi Kamatani, Akira Takemoto, Keith A. Boroevich, Kazuhiro Kakimi, Yusuke Kinugasa, Minoru Tanabe, Tatsuhiko Tsunoda   +11 more
doaj   +1 more source

Persistence and safety of anti-TNF biosimilars versus originators in immune-mediated inflammatory diseases: an observational study on the French National Health Data System

RMD Open
Objectives Biosimilar-originator equivalence has been demonstrated in phase 3 trials in a few indications of infliximab, etanercept and adalimumab. The objective of our study was to compare the persistence and safety of biosimilars versus originators in ...
Mahmoud Zureik, Lea Hoisnard, Emilie Sbidian, Hugo Jourdain   +3 more
doaj   +1 more source

Immune evasion by cancer stem cells [PDF]

Tumor immunity represents a new avenue for cancer therapy. Immune checkpoint inhibitors have successfully improved outcomes in several tumor types. In addition, currently, immune cell-based therapy is also attracting significant attention.
00403402, 100001720, 3368, シオタ, ゴウシ, Tsuchiya, Hiroyuki, 100000303, 土谷, 博之, Shiota, Goshi, 4866, ツチヤ, ヒロユキ, 汐田, 剛史, 70263457   +11 more
core   +1 more source

Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP [PDF]

, 2008
Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell.
Wiertz, E.J.H.J., Rezende, Marisa Marcondes, Thomas C Mettenleiter, Jacques J Neefjes, Wang, Ying, Koch, J., Mirjam H M Heemskerk, Loch Sandra, Marieke C Verweij, Daus, Franz, Nikolaus Osterrieder, Neefjes, J.J., Tampe, R., Chowdhury, Shafiqul I., Osterrieder, Nikolaus, Loch, S., Edwin Quinten, Rijsewijk, Frans A. M., Quinten, E., Neefjes, Jacques J., Ressing, Maaike E., Lipinska, A.D., Krystyna Bieńkowska-Szewczyk, Verweij Marieke C., Koch Joachim, Danijela Koppers-Lalic, Neefjes Jacques J., Wiertz, Emmanuel J. H. J., Koppers-Lalic, Danijela, Mettenleiter, T.C., Lipińska Andrea D., Rezende Marisa Marcondes, Ressing Maaike E., Emmanuel J H J Wiertz, Lipinska, Andrea D., Tampé Robert, Verweij, M.C., Ressing, M.E., Ying Wang, Wang, Y., Koch, Joachim, Heemskerk, Mirjam H. M., Sandra Loch, Marisa Marcondes Rezende, Tampé, Robert, Daus, F.J., Reits, E.A., Wiertz Emmanuel J. H. J., Shafiqul I Chowdhury, Loch, Sandra, Koppers-Lalic Danijela, Osterrieder, N., Quinten, Edwin, Rezende, M.M., Robert Tampé, Verweij, Marieke C., Joachim Koch, Franz Daus, Mettenleiter Thomas C., Bienkowska-Szewczyk, K., Rijsewijk, F.A.M., Eric A Reits, Heemskerk Mirjam H. M., Mettenleiter, Thomas C., Maaike E Ressing, Reits Eric A., Marcondes Rezende, Marisa, Chowdhury, S.I., Osterrieder Nikolaus, Daus Franz, Quinten Edwin, Koppers-Lalic, D., Reits, Eric A., Bienkowska-Szewczyk, Krystyna, Andrea D Lipińska, Frans A M Rijsewijk, Bieńkowska-Szewczyk Krystyna, Wang Ying, Rijsewijk Frans A. M., Heemskerk, M.H.M., Chowdhury Shafiqul I.   +80 more
core   +2 more sources

IL-18-Mediated Tumor Immune Evasion

Current Issues in Molecular Biology
Immune response evasion is one of the hallmark features of cancer, which is not only the basis for cancer progression and metastasis but also affects the clinical management of cancer.
Shuai Li, Chenxia Gao, Hongyu Zhao, Didi Wang, Shuang Liu   +4 more
doaj   +1 more source

Beware of Mycoplasma Anti-immunoglobulin Strategies

mBio, 2021
Mycoplasmas are small, genome-reduced bacteria. They are obligate parasites that can be found in a wide range of host species, including the majority of livestock animals and humans. Colonization of the host can result in a wide spectrum of outcomes.
Yonathan Arfi, Carole Lartigue, Pascal Sirand-Pugnet, Alain Blanchard   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Compound kushen injection inhibits immune evasion of hepatocellular carcinoma cells via reducing O-GlcNAcylation of Pd-L1

Autoimmunity
The advancement of hepatocellular carcinoma (HCC) is associated with metabolic reprogramming and immune escape. Compound kushen injection (CKI) is a cancer therapeutic agent with a long history.
Zhuo Lv, Jianyu Feng, Zijing Huang, Xia Fan, Yongheng Huang   +4 more
doaj   +1 more source