Results 31 to 40 of about 242,236 (303)
Islands of linkage in an ocean of pervasive recombination reveals two-speed evolution of human cytomegalovirus genomes [PDF]
, 2016 Human cytomegalovirus (HCMV) infects most of the population worldwide, persisting throughout the host's life in a latent state with periodic episodes of reactivation.
Atkinson, Claire +18 more
core +1 more source
Innate immune evasion by picornaviruses [PDF]
European Journal of Immunology, 2020 AbstractThe family Picornaviridae comprises a large number of viruses that cause disease in broad spectrum of hosts, which have posed serious public health concerns worldwide and led to significant economic burden. A comprehensive understanding of the virus‐host interactions during picornavirus infections will help to prevent and cure these diseases ...
Xiangle, Zhang +4 more
openaire +2 more sources
Subversion of Immune Response by Human Cytomegalovirus
Frontiers in Immunology, 2019 Human cytomegalovirus (HCMV) is the most common cause of congenital infections and is an important pathogen in immunocompromised individuals. Despite a robust host immune system, HCMV able to replicate, evade host defenses, establish latency for life.
A. Raj Kumar Patro
doaj +1 more source
Science, 2010 Malignant cells can induce the formation of lymphoid tissue–like structures that help the tumor evade host immunity.
Carlene L. Zindl, David D. Chaplin
openaire +1 more source
Immune subtypes and neoantigen-related immune evasion in advanced colorectal cancer
iScience, 2022 Summary: Elimination of cancerous cells by the immune system is an important mechanism of protection from cancer, however, its effectiveness can be reduced owing to development of resistance and evasion.
Toshitaka Sugawara +11 more
doaj +1 more source
Subversion of host innate immunity by uropathogenic Escherichia coli [PDF]
, 2016 Uropathogenic Escherichia coli (UPEC) cause the majority of community-onset urinary tract infections (UTI) and represent a major etiologic agent of healthcare-associated UTI.
Cavalieri +5 more
core +3 more sources
Rim Pathway-Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation [PDF]
, 2017 ACKNOWLEDGMENTS We acknowledge Jennifer Lodge, Woei Lam, and Rajendra Upadhya for developing and sharing the chitin and chitosan MTBH assay. We thank Todd Brennan of Duke University for providing MyD88-deficient mice.
Carol Munro +8 more
core +3 more sources
Annual Review of ImmunologyPoxviruses have evolved a wide array of mechanisms to evade the immune response, and we provide an overview of the different immunomodulatory strategies. Poxviruses prevent the recognition of viral DNA that triggers the immune responses and inhibit signaling pathways within the infected cell. A unique feature of poxviruses is the production of secreted
Hernáez, Bruno, Alcamí, Antonio
openaire +3 more sources
Overcoming Immune Evasion in Melanoma [PDF]
International Journal of Molecular Sciences, 2020 Melanoma is the most aggressive and dangerous form of skin cancer that develops from transformed melanocytes. It is crucial to identify melanoma at its early stages, in situ, as it is “curable” at this stage. However, after metastasis, it is difficult to treat and the five-year survival is only 25%.
Kevinn Eddy, Suzie Chen
openaire +2 more sources
RMD OpenObjectives Biosimilar-originator equivalence has been demonstrated in phase 3 trials in a few indications of infliximab, etanercept and adalimumab. The objective of our study was to compare the persistence and safety of biosimilars versus originators in ...
Mahmoud Zureik +3 more
doaj +1 more source