Results 11 to 20 of about 1,246,147 (266)

Immune Evasion Strategies of Schistosomes

Frontiers in Immunology, 2021
Human schistosomes combat the unique immune systems of two vastly different hosts during their indirect life cycles. In gastropod molluscs, they face a potent innate immune response composed of variable immune recognition molecules and highly phagocytic ...
Jacob R. Hambrook, Patrick C. Hanington
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Messenger RNA Sequence Rather than Protein Sequence Determines the Level of Self-synthesis and Antigen Presentation of the EBV-encoded Antigen, EBNA1 [PDF]

, 2012
peer-reviewedViruses establishing persistent latent infections have evolved various mechanisms to avoid immune surveillance. The Epstein-Barr virus-encoded nuclear antigen, EBNA1, expressed in all EBV-associated malignancies, modulates its own protein ...
David J Lynn, Judy T Tellam, Rajiv Khanna, David J. Lynn (107188), Lea Lekieffre, Lynn, David J, Khanna, Rajiv, Judy T. Tellam (107182), Zhong, Jie, Jie Zhong (39213), Tellam, Judy T, Jie Zhong, Rajiv Khanna (107190), Lea Lekieffre (107185), Lekieffre, Lea   +14 more
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Immune Evasion Mechanism and AXL

Frontiers in Oncology, 2021
Extensive interest in cancer immunotherapy is reported according to the clinical importance of CTLA-4 and (PD-1/PD-L1) [programmed death (PD) and programmed death-ligand (PD-L1)] in immune checkpoint therapies. AXL is a receptor tyrosine kinase expressed
Hye-Youn Son, Hwan-Kyu Jeong
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Filoviral Immune Evasion Mechanisms

Viruses, 2011
The Filoviridae family of viruses, which includes the genera Ebolavirus (EBOV) and Marburgvirus (MARV), causes severe and often times lethal hemorrhagic fever in humans. Filoviral infections are associated with ineffective innate antiviral responses as a
Christopher F. Basler, Gaya K. Amarasinghe, Craig S. Brown, Reed S. Shabman, Parameshwaran Ramanan, Daisy W. Leung   +5 more
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Immune Evasion of Mycoplasma bovis

Pathogens, 2021
Mycoplasma bovis (M. bovis) causes various chronic inflammatory diseases, including mastitis and bronchopneumonia, in dairy and feed cattle. It has been found to suppress the host immune response during infection, leading to the development of chronic ...
Hussam Askar, Shengli Chen, Huafang Hao, Xinmin Yan, Lina Ma, Yongsheng Liu, Yuefeng Chu   +6 more
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Innate immune evasion by alphaviruses

Frontiers in Immunology, 2022
Alphaviruses contain many human and animal pathogens, such as CHIKV, SINV, and VEEV. Accumulating evidence indicates that innate immunity plays an important role in response to alphaviruses infection.
Yihan Liu, Yihan Liu, Yihan Liu, Yupei Yuan, Yupei Yuan, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +7 more
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Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b [PDF]

, 2012
Upon host infection, the human pathogenic microbe Staphylococcus aureus (S. aureus) immediately faces innate immune reactions such as the activated complement system. Here, a novel innate immune evasion strategy of S. aureus is described.
Peter F. Zipfel, Christine Skerka, Kraiczy, Peter, Michael Reuter, Reuter, Michael, Skerka, Christine, Barthel, Diana, Diana Barthel, Koch, Tina K., Elsen, Jean van den, Böhm, Sascha, Zipfel, Peter F., Jean van den Elsen, Peter Kraiczy, Tina K Koch, Sascha Böhm, Peter F Zipfel, Tina K. Koch   +17 more
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Staphylococcus aureus uses the ArlRS and MgrA cascade to regulate immune evasion during skin infection

Cell Reports, 2021
Summary: Skin is one of the most common sites of host immune response against Staphylococcus aureus infection. Here, through a combination of in vitro assays, mouse models, and intravital imaging, we find that S.
Jakub M. Kwiecinski, Rachel M. Kratofil, Corey P. Parlet, Bas G.J. Surewaard, Paul Kubes, Alexander R. Horswill   +5 more
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Targeting PIM Kinases to Improve the Efficacy of Immunotherapy

Cells, 2022
The Proviral Integration site for Moloney murine leukemia virus (PIM) kinases is a family of serine/threonine kinases that regulates numerous signaling networks that promote cell growth, proliferation, and survival.
Amber N. Clements, Noel A. Warfel
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Subversion of Immune Response by Human Cytomegalovirus

Frontiers in Immunology, 2019
Human cytomegalovirus (HCMV) is the most common cause of congenital infections and is an important pathogen in immunocompromised individuals. Despite a robust host immune system, HCMV able to replicate, evade host defenses, establish latency for life.
A. Raj Kumar Patro
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