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Filoviral Immune Evasion Mechanisms [PDF]
The Filoviridae family of viruses, which includes the genera Ebolavirus (EBOV) and Marburgvirus (MARV), causes severe and often times lethal hemorrhagic fever in humans. Filoviral infections are associated with ineffective innate antiviral responses as a
Christopher F. Basler +5 more
doaj +3 more sources
Immune Evasion Strategies of Schistosomes [PDF]
Human schistosomes combat the unique immune systems of two vastly different hosts during their indirect life cycles. In gastropod molluscs, they face a potent innate immune response composed of variable immune recognition molecules and highly phagocytic ...
Jacob R. Hambrook, Patrick C. Hanington
doaj +3 more sources
Innate immune evasion by alphaviruses
Alphaviruses contain many human and animal pathogens, such as CHIKV, SINV, and VEEV. Accumulating evidence indicates that innate immunity plays an important role in response to alphaviruses infection.
Yihan Liu +7 more
doaj +3 more sources
Immune Evasion Strategies of Glioblastoma [PDF]
Glioblastoma (GBM) is the most devastating brain tumor, with associated poor prognosis. Despite advances in surgery and chemoradiation, the survival of afflicted patients has not improved significantly in the past three decades.
Seyed-Mostafa eRazavi +5 more
doaj +3 more sources
Predictive Virtual Infection Modeling of Fungal Immune Evasion in Human Whole Blood
Bloodstream infections by the human-pathogenic fungi Candida albicans and Candida glabrata increasingly occur in hospitalized patients and are associated with high mortality rates.
Maria T. E. Prauße +15 more
doaj +1 more source
Spirochetal Lipoproteins and Immune Evasion. [PDF]
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani +2 more
core +1 more source
Immune Evasion of G-CSF and GM-CSF in Lung Cancer [PDF]
Tumor immune evasion is a complex process that involves various mechanisms, such as antigen recognition restriction, immune system suppression, and T cell exhaustion.
Yeonhee Park, Chaeuk Chung
doaj +1 more source
The essential role of mitochondrial dynamics in antiviral immunity. [PDF]
Viruses alter cellular physiology and function to establish cellular environment conducive for viral proliferation. Viral immune evasion is an essential aspect of viral persistence and proliferation.
Ahn, Dae-Gyun +3 more
core +2 more sources
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+FoxP3+ regulatory T cells activation [PDF]
Rationale: Loss of histone macroH2A1 induces appearance of cancer stem cells (CSCs)-like cells in hepatocellular carcinoma (HCC). How CSCs interact with the tumor microenvironment and the adaptive immune system is unclear. Methods: We screened aggressive
Drovakova A. +11 more
core +1 more source
Lymphoma: Immune Evasion Strategies [PDF]
While the cellular origin of lymphoma is often characterized by chromosomal translocations and other genetic aberrations, its growth and development into a malignant neoplasm is highly dependent upon its ability to escape natural host defenses.
Upadhyay, Ranjan +5 more
openaire +2 more sources

