Results 11 to 20 of about 155,116 (264)
Innate immune evasion by filoviruses
Virology, 2015 Ebola viruses and Marburg viruses, members of the filovirus family, cause severe hemorrhagic fever. The ability of these viruses to potently counteract host innate immune responses is thought to be an important component of viral pathogenesis.
Basler, Christopher F.
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Immune evasion by gamma-herpesviruses
Current Opinion in Immunology, 2004 Persistent viruses, such as herpesviruses, transmit infection by evading cytotoxic T cells during lytic replication. The gamma-herpesviruses additionally evade T cells during the proliferation of latently infected lymphocytes to establish a persistent ...
Stevenson, Philip G.
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Innate immune evasion by picornaviruses [PDF]
European Journal of Immunology, 2020 AbstractThe family Picornaviridae comprises a large number of viruses that cause disease in broad spectrum of hosts, which have posed serious public health concerns worldwide and led to significant economic burden. A comprehensive understanding of the virus‐host interactions during picornavirus infections will help to prevent and cure these diseases ...
Xiangle, Zhang +4 more
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Overcoming Immune Evasion in Melanoma [PDF]
International Journal of Molecular Sciences, 2020 Melanoma is the most aggressive and dangerous form of skin cancer that develops from transformed melanocytes. It is crucial to identify melanoma at its early stages, in situ, as it is “curable” at this stage. However, after metastasis, it is difficult to treat and the five-year survival is only 25%.
Kevinn Eddy, Suzie Chen
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Immune Evasion Strategies of Schistosomes [PDF]
Frontiers in Immunology, 2021 Human schistosomes combat the unique immune systems of two vastly different hosts during their indirect life cycles. In gastropod molluscs, they face a potent innate immune response composed of variable immune recognition molecules and highly phagocytic hemocytes.
Jacob R. Hambrook, Patrick C. Hanington
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Innate immune evasion by alphaviruses
Frontiers in Immunology, 2022 Alphaviruses contain many human and animal pathogens, such as CHIKV, SINV, and VEEV. Accumulating evidence indicates that innate immunity plays an important role in response to alphaviruses infection. In parallel, alphaviruses have evolved many strategies to evade host antiviral innate immunity.
Yihan Liu +7 more
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Human cytomegalovirus immunity and immune evasion
Virus Research, 2011 Human cytomegalovirus (HCMV) infection induces both innate immune responses including Natural Killer cells as well as adaptive humoral and cell mediated (CD4+ helper, CD8+ cytotoxic and γδ T cell) responses which lead to the resolution of acute primary infection.
Sarah E, Jackson +2 more
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Viral mechanisms of immune evasion [PDF]
Immunology Today, 2000 During the millions of years they have coexisted with their hosts, viruses have learned how to manipulate host immune control mechanisms. Viral gene functions provide an overview of many relevant principles in cell biology and immunology. Our knowledge of viral gene functions must be integrated into virus-host interaction networks to understand viral ...
Alcami, Antonio, Koszinowski, Ulrich H.
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Filoviral Immune Evasion Mechanisms [PDF]
Viruses, 2011 The Filoviridae family of viruses, which includes the genera Ebolavirus (EBOV) and Marburgvirus (MARV), causes severe and often times lethal hemorrhagic fever in humans. Filoviral infections are associated with ineffective innate antiviral responses as a result of virally encoded immune antagonists, which render the host incapable of mounting effective
Christopher F. Basler +5 more
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Pathogen evasion of social immunity
Nature Ecology & Evolution, 2023 AbstractTreating sick group members is a hallmark of collective disease defence in vertebrates and invertebrates alike. Despite substantial effects on pathogen fitness and epidemiology, it is still largely unknown how pathogens react to the selection pressure imposed by care intervention.
Miriam Stock +8 more
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