Results 21 to 30 of about 1,940,572 (373)

Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution

Nature Ecology & Evolution, 2023
Mutations in the SARS-CoV-2 genome could confer resistance to pre-existing antibodies and/or increased transmissibility. The recently emerged Omicron subvariants exhibit a strong tendency for immune evasion, suggesting adaptive evolution.
Wentai Ma, Haoyi Fu, F. Jian, Yunlong Cao, Mingkun Li   +4 more
semanticscholar   +1 more source

Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas

BMC Cancer, 2022
Background Although intrinsic immune-evasion is important in cancer proliferation, metastasis and response to treatment, it is unclear whether intrinsic immune-evasion patterns of gliomas can aid in predicting clinical prognosis and determining treatment.
Zewei Tu, Qiankun Ji, Qing Han, Xiaoyan Long, Jingying Li, Lei Wu, Kai Huang, Xingen Zhu   +7 more
doaj   +1 more source

Immune evasion and provocation by Mycobacterium tuberculosis

Nature Reviews Microbiology, 2022
Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host immune response and be transmitted to uninfected individuals.
P. Chandra, Steven J. Grigsby, J. Philips   +2 more
semanticscholar   +1 more source

Evasion of the Cell-Mediated Immune Response by Alphaherpesviruses

Viruses, 2020
Alphaherpesviruses cause various diseases and establish life-long latent infections in humans and animals. These viruses encode multiple viral proteins and miRNAs to evade the host immune response, including both innate and adaptive immunity ...
Naoto Koyanagi, Yasushi Kawaguchi
doaj   +1 more source

Extrachromosomal DNA formation enables tumor immune escape potentially through regulating antigen presentation gene expression

Scientific Reports, 2022
Extrachromosomal DNA (ecDNA) is a type of circular and tumor specific genetic element. EcDNA has been reported to display open chromatin structure, facilitate oncogene amplification and genetic material unequal segregation, and is associated with poor ...
Tao Wu, Chenxu Wu, Xiangyu Zhao, Guangshuai Wang, Wei Ning, Ziyu Tao, Fuxiang Chen, Xue-Song Liu   +7 more
doaj   +1 more source

The mechanisms on evasion of anti-tumor immune responses in gastric cancer

Frontiers in Oncology, 2022
The immune system and the tumor have been at each other’s throats for so long that the neoplasm has learned to avoid detection and avoid being attacked, which is called immune evasion.
Junyang Wang, Tong Liu, Tao Huang, Mei Shang, Xudong Wang   +4 more
doaj   +1 more source

Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement

Science, 2022
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern evades antibody-mediated immunity that comes from vaccination or infection with earlier variants due to accumulation of numerous spike mutations.
M. McCallum, N. Czudnochowski, Laura E. Rosen, Samantha K. Zepeda, John E. Bowen, A. Walls, Kevin Hauser, Anshu Joshi, Cameron Stewart, J. Dillen, Abigail E. Powell, T. I. Croll, Jay C. Nix, Herbert W. Virgin, Davide Corti, G. Snell, D. Veesler   +16 more
semanticscholar   +1 more source

In silico structural homology modeling and functional characterization of Mycoplasma gallisepticum variable lipoprotein hemagglutin proteins

Frontiers in Veterinary Science, 2022
Mycoplasma gallisepticum variable lipoprotein hemagglutin (vlhA) proteins are crucial for immune evasion from the host cells, permitting the persistence and survival of the pathogen.
Susithra Priyadarshni Mugunthan, Mani Chandra Harish   +1 more
doaj   +1 more source

SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern

Science, 2021
SARS-CoV-2 from alpha to epsilon As battles to contain the COVID-19 pandemic continue, attention is focused on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that have been deemed variants of concern because ...
M. McCallum, J. Bassi, A. De Marco, Alex Chen, A. Walls, J. di Iulio, M. A. Tortorici, M. Navarro, C. Silacci-Fregni, C. Saliba, Kaitlin R. Sprouse, Maria L. Agostini, D. Pinto, K. Culap, S. Bianchi, S. Jaconi, E. Cameroni, John E. Bowen, Sasha W. Tilles, M. Pizzuto, Sonja Bernasconi Guastalla, G. Bona, A. F. Pellanda, C. Garzoni, W. V. Van Voorhis, Laura E. Rosen, G. Snell, A. Telenti, H. Virgin, L. Piccoli, D. Corti, D. Veesler   +31 more
semanticscholar   +1 more source

Activation of immune evasion machinery is a part of the process of malignant transformation of human cells. [PDF]

, 2023
Malignant transformation of human cells is associated with their re-programming which results in uncontrolled proliferation and in the same time biochemical activation of immunosuppressive pathways which form cancer immune evasion machinery.
Abooali, Maryam, Bartenstein, Andreas, Berger, Steffen M, Cholewa, Dietmar, Fasler-Kan, Elizaveta, Milošević, Milan, Ruggiero, Sabrina, Schlichtner, Stephanie, Sumbayev, Vadim V, Yasinska, Inna M   +9 more
core   +2 more sources