Results 11 to 20 of about 2,585,977 (417)

Spatially variant immune infiltration scoring in human cancer tissues

npj Precision Oncology, 2022
The Immunoscore is a method to quantify the immune cell infiltration within cancers to predict the disease prognosis. Previous immune profiling approaches relied on limited immune markers to establish patients’ tumor immunity.
Mayar Allam, Thomas Hu, Jeongjin Lee, Jeffrey Aldrich, Sunil S. Badve, Yesim Gökmen-Polar, Manali Bhave, Suresh S. Ramalingam, Frank Schneider, Ahmet F. Coskun   +9 more
doaj   +2 more sources

Immune infiltration in aggressive papillary craniopharyngioma: High infiltration but low action

Frontiers in Immunology, 2022
Papillary craniopharyngiomas (PCPs) are biologically benign but clinically aggressive lesions hence affect the quality of life. The expression of inflammatory mediators and regulation of the immune microenvironment in PCPs have not been investigated much.
Yanfei Jia, Lin Ma, Kefan Cai, Bochao Zhang, Wentao Wu, Youchao Xiao, Ning Qiao, Siming Ru, Lei Cao, Hua Gao, Songbai Gui   +10 more
openaire   +4 more sources

Identification of immune infiltration-related genes as prognostic indicators for hepatocellular carcinoma

BMC Cancer, 2022
Hepatocellular carcinoma (HCC) has a high degree of malignancy and a poor prognosis. Immune infiltration-related genes have shown good predictive value in the prognosis of many solid tumours.
Kunfu Dai, Chao Liu, Ge Guan, Jinzhen Cai, Liqun Wu   +4 more
doaj   +2 more sources

Immune Landscape of Invasive Ductal Carcinoma Tumor Microenvironment Identifies a Prognostic and Immunotherapeutically Relevant Gene Signature [PDF]

Frontiers in Oncology, 2019
Background: Invasive ductal carcinoma (IDC) is a clinically and molecularly distinct disease. Tumor microenvironment (TME) immune phenotypes play crucial roles in predicting clinical outcomes and therapeutic efficacy.
Bao, Xuanwen, Li, Xin, Shi, Run, Wang, Yanfang, Xin, Shan, Zhang, Kai, Zhao, Yanbo   +6 more
core   +3 more sources

Roles of pyroptosis and immune infiltration in aortic dissection

Frontiers in Molecular Biosciences
Introduction: Aortic dissection (AD) is often fatal, and its pathogenesis involves immune infiltration and pyroptosis, though the molecular pathways connecting these processes remain unclear. This study aimed to investigate the role of immune infiltration and pyroptosis in AD pathogenesis using bioinformatics analysis.Methods: Two Gene Expression ...
Xiaogang Ge, Qiqi Cai, Yangyang Cai, Caiguo Mou, Junhui Fu, Feng Lin   +5 more
openaire   +4 more sources

Hepcidin Upregulation in Lung Cancer: A Potential Therapeutic Target Associated With Immune Infiltration

Frontiers in Immunology, 2021
Lung cancer has the highest death rate among cancers globally. Hepcidin is a fascinating regulator of iron metabolism; however, the prognostic value of hepcidin and its correlation with immune cell infiltration in lung cancer remain unclear.
Yumei Fan, Bing Liu, Fei Chen, Zhiyuan Song, Bihui Han, Yanxiu Meng, Jiajie Hou, Pengxiu Cao, Yanzhong Chang, Ke Tan   +9 more
doaj   +2 more sources

Germline features associated with immune infiltration in solid tumors [PDF]

Cell Reports, 2019
ABSTRACTGiven the clinical success of immune checkpoint blockade (ICB) across a diverse set of solid tumors, and the emerging role for different immune infiltrates in contributing to response to ICB, a comprehensive assessment of the properties that dictate immune infiltrations may reveal new biological insights and inform the development of new ...
Saud H. AlDubayan, Saud H. AlDubayan, Saud H. AlDubayan, Sohini Ramachandran, Matthew A. Reyna, Matthew A. Reyna, Eliezer M. Van Allen, Eliezer M. Van Allen, Sahar Shahamatdar, Meng Xiao He, Meng Xiao He, Alexander Gusev, Alexander Gusev, Alexander Gusev   +13 more
openaire   +7 more sources

Integrated single cell and bulk sequencing analysis identifies tumor reactive CXCR6+ CD8 T cells as a predictor of immune infiltration and immunotherapy outcomes in hepatocellular carcinoma

Frontiers in Oncology, 2023
BackgroundVarious immune cell types in the tumor microenvironment (TME) of hepatocellular carcinoma (HCC) have been identified as important parameters associated with prognosis and responsiveness to immunotherapy.
Xiaogang Li, Xiaogang Li, Zheng Gao, Zheng Gao, Jiafeng Chen, Jiafeng Chen, Shanru Feng, Shanru Feng, Xuanming Luo, Yinghong Shi, Yinghong Shi, Zheng Tang, Zheng Tang, Weiren Liu, Weiren Liu, Xin Zhang, Xin Zhang, Ao Huang, Ao Huang, Qiang Gao, Qiang Gao, Aiwu Ke, Aiwu Ke, Jian Zhou, Jian Zhou, Jian Zhou, Jia Fan, Jia Fan, Xiutao Fu, Xiutao Fu, Zhenbin Ding, Zhenbin Ding, Zhenbin Ding   +32 more
doaj   +1 more source

Development of an Immune-Related Gene Signature for Prognosis in Melanoma

Frontiers in Oncology, 2021
Melanoma remains a potentially deadly malignant tumor. The incidence of melanoma continues to rise. Immunotherapy has become a new treatment method and is widely used in a variety of tumors. Original melanoma data were downloaded from TCGA.
Jia-An Zhang, Xu-Yue Zhou, Dan Huang, Chao Luan, Heng Gu, Mei Ju, Kun Chen   +6 more
doaj   +1 more source

The role of molecular subtypes and immune infiltration characteristics based on disulfidptosis-associated genes in lung adenocarcinoma

Aging, 2023
Lung adenocarcinoma (LUAD) is the most common type of lung cancer which accounts for about 40% of all lung cancers. Early detection, risk stratification and treatment are important for improving outcomes for LUAD.
Cui Qi, Jia-Qi Ma, Jinjin Sun, Xiaolin Wu, Jian Ding   +4 more
semanticscholar   +1 more source