Results 11 to 20 of about 662,585 (256)

Immune infiltration in aggressive papillary craniopharyngioma: High infiltration but low action

Frontiers in Immunology, 2022
Papillary craniopharyngiomas (PCPs) are biologically benign but clinically aggressive lesions hence affect the quality of life. The expression of inflammatory mediators and regulation of the immune microenvironment in PCPs have not been investigated much.
Yanfei Jia, Lin Ma, Kefan Cai, Bochao Zhang, Wentao Wu, Youchao Xiao, Ning Qiao, Siming Ru, Lei Cao, Hua Gao, Songbai Gui   +10 more
doaj   +3 more sources

Immune infiltrating cells in duodenal cancers [PDF]

Journal of Translational Medicine, 2020
Abstract Background Duodenal adenocarcinoma (DA) is a rare yet aggressive malignancy, with increasing incidence in the last decades. Its low frequency has hampered a thorough understanding of the pathogenesis of the disease and of its biology, limiting the identification of tailored therapeutic options.
Donisi, G., Capretti, G., Cortese, N., Rigamonti, A., Gavazzi, F., Nappo, G., Pulvirenti A, Sollai, M., Spaggiari, P., Zerbi, A., Marchesi, F   +20 more
openaire   +3 more sources

DFNA5 regulates immune cells infiltration and exhaustion [PDF]

Cancer Cell International, 2022
Abstract Background DFNA5 (GSDME) belongs to Gasdermin familily that is involved in a variety of cancers and triggers cell pyroptosis after chemical treatment. However, the relationship in DFNA5 between prognosis and immune cells in diverse cancers has been receiving little attention.
Jian Hu, Wenceng Pei, Minren Jiang, Ying Huang, Fuyun Dong, Zhenyou Jiang, Ying Xu, Zihuang Li   +7 more
openaire   +3 more sources

Immune infiltration in renal cell carcinoma [PDF]

Cancer Science, 2019
Immune infiltration of tumors is closely associated with clinical outcome in renal cell carcinoma (RCC). Tumor‐infiltrating immune cells (TIICs) regulate cancer progression and are appealing therapeutic targets. The purpose of this study was to determine the composition of TIICs in RCC and further reveal the independent prognostic values of TIICs ...
Shichao Zhang, Erdong Zhang, Jinhua Long, Zuquan Hu, Jian Peng, Lina Liu, Fuzhou Tang, Long Li, Yan Ouyang, Zhu Zeng   +9 more
openaire   +2 more sources

Tumor Immunometabolism Characterization in Ovarian Cancer With Prognostic and Therapeutic Implications

Frontiers in Oncology, 2021
Metabolic dysregulation in the tumor microenvironment has significant impact on immune infiltration and immune responses. However, interaction between immunity and metabolism in the ovarian microenvironment requires further exploration. We constructed an
Miner Yang, Gaowen Chen, Kunjie Gao, Yifeng Wang   +3 more
doaj   +1 more source

Immune cell infiltration landscape and immune marker molecular typing in preeclampsia [PDF]

Bioengineered, 2021
Preeclampsia (PE) is an important topic in obstetrics. In this study, we used weighted gene co-expression network analysis (WGCNA) to screen the key modules related to immune cell infiltration and to identify the hub genes for the molecular subtyping of PE. We first downloaded a set of PE transcriptional data (GSE75010; 157 samples: 80 PE and 77 non-PE)
Meng, YiLin, Li, Chuang, Liu, Cai-Xia
openaire   +2 more sources

Identification and Verification of Immune-Related Gene Prognostic Signature Based on ssGSEA for Osteosarcoma

Frontiers in Oncology, 2020
Osteosarcoma is the most common malignant bone tumor in children and adolescence. Multiple immune-related genes have been reported in different cancers.
Bo Xiao, Bo Xiao, Liyan Liu, Liyan Liu, Aoyu Li, Aoyu Li, Cheng Xiang, Cheng Xiang, Pingxiao Wang, Pingxiao Wang, Hui Li, Hui Li, Tao Xiao, Tao Xiao   +13 more
doaj   +1 more source

Immune Infiltration in Invasive Lobular Breast Cancer [PDF]

JNCI: Journal of the National Cancer Institute, 2018
Invasive lobular breast cancer (ILC) is the second most common histological subtype of breast cancer after invasive ductal cancer (IDC). Here, we aimed at evaluating the prevalence, levels, and composition of tumor-infiltrating lymphocytes (TILs) and their association with clinico-pathological and outcome variables in ILC, and to compare them with IDC ...
Desmedt, Christine, Salgado, Roberto, Fornili, Marco, Pruneri, Giancarlo, Van den Eynden, Gert, Zoppoli, Gabriele, Rothe, Francoise, Buisseret, Laurence, Garaud, Soizic, Willard-Gallo, Karen, Brown, David, Bareche, Yacine, Rouas, Ghizlane, Galant, Christine, Bertucci, Francois, Loi, Sherene, Viale, Giuseppe, Di Leo, Angelo, Green, Andrew R., Ellis, Ian O., Rakha, Emad A., Larsimont, Denis, Biganzoli, Elia, Sotiriou, Christos   +23 more
openaire   +7 more sources

The Prognostic Value of GNG7 in Colorectal Cancer and Its Relationship With Immune Infiltration

Frontiers in Genetics, 2022
Background: G Protein Subunit Gamma 7 (GNG7) is an important gene that regulates cell proliferation and induces apoptosis. However, the correlation between GNG7 expression and immune infiltration as well as patient prognosis of colorectal cancer (CRC ...
Can Fang, Rulei Zhong, Chenyang Qiu, Bing-bing Zou   +3 more
doaj   +1 more source

TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain [PDF]

, 2016
Background: The relationship between the brain and the immune system has become increasingly topical as, although it is immune-specialised, the CNS is not free from the influences of the immune system.
A Boivin, A Constant, A Walter, AD Bachstetter, Alison McColl, B Winner, BT Fife, C Callewaere, C D'Mello, C Gemma, CA Thomson, Carolyn A. Thomson, CP Marques, CS McKimmie, CT Ekdahl, D Michlmayr, D Michlmayr, EE Ubogu, G Banisadr, G Banisadr, Gerard J. Graham, JH Dufour, JL Teeling, Jonathan Cavanagh, JS Cameron, JS Snyder, JT Rogers, L Azzi, L Cartier, L Fits van der, Louis Nerurkar, M Baggiolini, M Udina, ML Monje, MM Lee, N Andrews, Q Liu, R Dantzer, R Deacon, R Krishnan, R Rola, RM Deacon, RM Ransohoff, S Baraldi, S Goethals, S Potvin, S Tyring, SM O'Brien, U Patel, U Puntener, W Huang da, W Huang da, W Rostene, WJ Karpus   +53 more
core   +2 more sources