Results 11 to 20 of about 2,772,829 (401)

Immune infiltration and prostate cancer [PDF]

Frontiers in Oncology, 2015
It is becoming increasingly clear that inflammation influences prostate cancer development and that immune cells are among the primary drivers of this effect.
Amy eStrasner, Michael eKarin
doaj   +10 more sources

Barriers to immune cell infiltration in tumors

Journal for ImmunoTherapy of Cancer, 2023
Increased immune cell infiltration into tumors is associated with improved patient survival and predicts response to immune therapies. Thus, identification of factors that determine the extent of immune infiltration is crucial, so that methods to ...
Craig L Slingluff, Marit M Melssen, Natasha D Sheybani, Katie M Leick   +3 more
doaj   +3 more sources

Immune infiltration in aggressive papillary craniopharyngioma: High infiltration but low action

Frontiers in Immunology, 2022
Papillary craniopharyngiomas (PCPs) are biologically benign but clinically aggressive lesions hence affect the quality of life. The expression of inflammatory mediators and regulation of the immune microenvironment in PCPs have not been investigated much.
Yanfei Jia, Lin Ma, Kefan Cai, Bochao Zhang, Wentao Wu, Youchao Xiao, Ning Qiao, Siming Ru, Lei Cao, Hua Gao, Songbai Gui   +10 more
doaj   +3 more sources

Spatially variant immune infiltration scoring in human cancer tissues

npj Precision Oncology, 2022
The Immunoscore is a method to quantify the immune cell infiltration within cancers to predict the disease prognosis. Previous immune profiling approaches relied on limited immune markers to establish patients’ tumor immunity.
Mayar Allam, Thomas Hu, Jeongjin Lee, Jeffrey Aldrich, Sunil S. Badve, Yesim Gökmen-Polar, Manali Bhave, Suresh S. Ramalingam, Frank Schneider, Ahmet F. Coskun   +9 more
doaj   +2 more sources

Immune infiltration and immunophenotyping in atrial fibrillation

Aging, 2023
Atrial fibrillation (AF) is a relatively common arrhythmia in clinical practice. Although significant progress has been achieved in the treatment of AF and its associated complications, research on AF prevention lags behind, mainly due to the lack of a ...
Yuqing Tian, Shiying Liu, Yanan Zhang, Jiefu Yang, Peiyao Guo, Hongchao Zhang, Xue Yu, T. Zou   +7 more
semanticscholar   +3 more sources

Computed tomography-based radiomics predicts prognostic and treatment-related levels of immune infiltration in the immune microenvironment of clear cell renal cell carcinoma [PDF]

BMC Medical Imaging
Objectives The composition of the tumour microenvironment is very complex, and measuring the extent of immune cell infiltration can provide an important guide to clinically significant treatments for cancer, such as immune checkpoint inhibition therapy ...
Shiyan Song, Wenfei Ge, Xiaochen Qi, Xiangyu Che, Qifei Wang, Guangzhen Wu   +5 more
doaj   +2 more sources

Integrated single cell and bulk sequencing analysis identifies tumor reactive CXCR6+ CD8 T cells as a predictor of immune infiltration and immunotherapy outcomes in hepatocellular carcinoma

Frontiers in Oncology, 2023
BackgroundVarious immune cell types in the tumor microenvironment (TME) of hepatocellular carcinoma (HCC) have been identified as important parameters associated with prognosis and responsiveness to immunotherapy.
Xiaogang Li, Xiaogang Li, Zheng Gao, Zheng Gao, Jiafeng Chen, Jiafeng Chen, Shanru Feng, Shanru Feng, Xuanming Luo, Yinghong Shi, Yinghong Shi, Zheng Tang, Zheng Tang, Weiren Liu, Weiren Liu, Xin Zhang, Xin Zhang, Ao Huang, Ao Huang, Qiang Gao, Qiang Gao, Aiwu Ke, Aiwu Ke, Jian Zhou, Jian Zhou, Jian Zhou, Jia Fan, Jia Fan, Xiutao Fu, Xiutao Fu, Zhenbin Ding, Zhenbin Ding, Zhenbin Ding   +32 more
doaj   +1 more source

Development of an Immune-Related Gene Signature for Prognosis in Melanoma

Frontiers in Oncology, 2021
Melanoma remains a potentially deadly malignant tumor. The incidence of melanoma continues to rise. Immunotherapy has become a new treatment method and is widely used in a variety of tumors. Original melanoma data were downloaded from TCGA.
Jia-An Zhang, Xu-Yue Zhou, Dan Huang, Chao Luan, Heng Gu, Mei Ju, Kun Chen   +6 more
doaj   +1 more source

The role of molecular subtypes and immune infiltration characteristics based on disulfidptosis-associated genes in lung adenocarcinoma

Aging, 2023
Lung adenocarcinoma (LUAD) is the most common type of lung cancer which accounts for about 40% of all lung cancers. Early detection, risk stratification and treatment are important for improving outcomes for LUAD.
Cui Qi, Jia-Qi Ma, Jinjin Sun, Xiaolin Wu, Jian Ding   +4 more
semanticscholar   +1 more source

Association of High Tumor Mutation Burden in Non–Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels

JAMA Oncology, 2022
Key Points Question Is tumor mutation burden (TMB) associated with improved outcomes of programmed cell death–1 (PD-1)/programmed death ligand–1 (PD-L1) inhibition across PD-L1 expression levels in non–small cell lung cancer (NSCLC)?
B. Ricciuti, Xinan Wang, J. Alessi, H. Rizvi, N. Mahadevan, Yvonne Y. Li, Andrew Polio, James Lindsay, R. Umeton, Rileen Sinha, N. Vokes, G. Recondo, G. Lamberti, M. Lawrence, V. Vaz, G. Leonardi, A. Plodkowski, H. Gupta, A. Cherniack, M. Tolstorukov, B. Sharma, K. Felt, J. Gainor, Arvind Ravi, G. Getz, K. Schalper, B. Henick, P. Forde, V. Anagnostou, P. Jänne, E. V. Van Allen, M. Nishino, L. Sholl, D. Christiani, Xihong Lin, S. Rodig, M. Hellmann, M. Awad   +37 more
semanticscholar   +1 more source