Results 31 to 40 of about 2,772,829 (401)

Identification and Validation of Immune Infiltration Phenotypes in Laryngeal Squamous Cell Carcinoma by Integrative Multi-Omics Analysis

Frontiers in Immunology, 2022
BackgroundLaryngeal squamous cell carcinoma (LSCC) is one of the world’s most common head and neck cancer. However, the immune infiltration phenotypes of LSCC have not been well investigated.MethodsThe multi-omics data of LSCC were obtained from the TCGA
Li Yan, Xiaole Song, Gang Yang, Lifen Zou, Yi Zhu, Xiaoshen Wang   +5 more
doaj   +1 more source

Role of ferroptosis and immune infiltration in intervertebral disc degeneration: novel insights from bioinformatics analyses

Frontiers in Cell and Developmental Biology, 2023
Background: Intervertebral disc degeneration (IVDD), which contributes to stenosis of the spinal segment, commonly causes lower back pain. The process of IVDD degradation entails gradual structural adjustments accompanied by extreme transformations in ...
Xiao-Wei Liu, Hao-Wei Xu, Yu-Yang Yi, Shu-Bao Zhang, Shan-Jin Wang   +4 more
semanticscholar   +1 more source

Cervical cancer immune infiltration microenvironment identification, construction of immune scores, assisting patient prognosis and immunotherapy

Frontiers in Immunology, 2023
Background The immune microenvironment is of great significance in cervical cancer. However, there is still a lack of systematic research on the immune infiltration environment of cervical cancer.
Shijie Yao, Liyang Zhao, Siming Chen, Hua Wang, Yang Gao, Ningyi Shao, Mengyuan Dai, Hongbing Cai   +7 more
semanticscholar   +1 more source

The development of endoplasmic reticulum-related gene signatures and the immune infiltration analysis of sepsis

Frontiers in Immunology, 2023
Background Sepsis is a complex condition involving multiorgan failure, resulting from the hosts’ deleterious systemic immune response to infection.
Yi Zhou, Yifang Chen, Jianbo Li, Zai-Lin Fu, Q. Chen, Wei Zhang, Huan-Min Luo, Minghua Xie   +7 more
semanticscholar   +1 more source

Immune infiltration in renal cell carcinoma [PDF]

Cancer Science, 2019
Immune infiltration of tumors is closely associated with clinical outcome in renal cell carcinoma (RCC). Tumor‐infiltrating immune cells (TIICs) regulate cancer progression and are appealing therapeutic targets. The purpose of this study was to determine the composition of TIICs in RCC and further reveal the independent prognostic values of TIICs ...
Shichao Zhang, Erdong Zhang, Jinhua Long, Zuquan Hu, Jian Peng, Lina Liu, Fuzhou Tang, Long Li, Yan Ouyang, Zhu Zeng   +9 more
openaire   +2 more sources

Comprehensive analysis of cuproptosis-related genes in immune infiltration in ischemic stroke

Frontiers in Neurology, 2023
Background Immune infiltration plays an important role in the course of ischemic stroke (IS) progression. Cuproptosis is a newly discovered form of programmed cell death.
Xuehui Fan, Hongping Chen, Fangchao Jiang, Chen Xu, Yingjun Wang, Haining Wang, Meng Li, Wane Wei, Jihe Song, D. Zhong, Guozhong Li   +10 more
semanticscholar   +1 more source

CD86 Is Associated with Immune Infiltration and Immunotherapy Signatures in AML and Promotes Its Progression

Journal of Oncology, 2023
Background Cluster of differentiation 86 (CD86), also known as B7-2, is a molecule expressed on antigen-presenting cells that provides the costimulatory signals required for T cell activation and survival.
Qianqian Zhang, Ruixue Ma, Huimin Chen, Wen-juan Guo, Zhenyu Li, K. Xu, Wei Chen   +6 more
semanticscholar   +1 more source

Mechanism of immune infiltration in synovial tissue of osteoarthritis: a gene expression-based study

Journal of Orthopaedic Surgery and Research, 2023
Background Osteoarthritis is a chronic degenerative joint disease, and increasing evidences suggest that the pathogenic mechanism involves immune system and inflammation.
Qingyu Zhang, Chao Sun, Xuchang Liu, Chao Zhu, Chuncheng Ma, Rongjie Feng   +5 more
semanticscholar   +1 more source

Identification of specific prognostic markers for lung squamous cell carcinoma based on tumor progression, immune infiltration, and stem index

Frontiers in Immunology, 2023
Introduction Lung squamous cell carcinoma (LUSC) is a unique subform of nonsmall cell lung cancer (NSCLC). The lack of specific driver genes as therapeutic targets leads to worse prognoses in patients with LUSC, even with chemotherapy, radiotherapy, or ...
Rihan Wu, Ru Ma, Xiaojun Duan, Jiandong Zhang, Kexin Li, Lei Yu, Mingyang Zhang, P. Liu, C. Wang   +8 more
semanticscholar   +1 more source

Tumor Immunometabolism Characterization in Ovarian Cancer With Prognostic and Therapeutic Implications

Frontiers in Oncology, 2021
Metabolic dysregulation in the tumor microenvironment has significant impact on immune infiltration and immune responses. However, interaction between immunity and metabolism in the ovarian microenvironment requires further exploration. We constructed an
Miner Yang, Gaowen Chen, Kunjie Gao, Yifeng Wang   +3 more
doaj   +1 more source