Results 41 to 50 of about 2,772,829 (401)
Frontiers in Immunology, 2023 Background IPF is an undetermined, progressive lung disease. Necroptosis is a type of programmed apoptosis, which involved in the pathogenesis of lung diseases like COPD and ARDS. However, necroptosis in IPF have not been adequately studied.
Hongzuo Chen +7 more
semanticscholar +1 more source
Immune cell infiltration landscape and immune marker molecular typing in preeclampsia [PDF]
Bioengineered, 2021 Preeclampsia (PE) is an important topic in obstetrics. In this study, we used weighted gene co-expression network analysis (WGCNA) to screen the key modules related to immune cell infiltration and to identify the hub genes for the molecular subtyping of PE. We first downloaded a set of PE transcriptional data (GSE75010; 157 samples: 80 PE and 77 non-PE)
Meng, YiLin, Li, Chuang, Liu, Cai-Xia
openaire +2 more sources
Frontiers in Oncology, 2020 Osteosarcoma is the most common malignant bone tumor in children and adolescence. Multiple immune-related genes have been reported in different cancers.
Bo Xiao +13 more
doaj +1 more source
BMC Cancer, 2023 Background Tumor microenvironment (TME) is of great importance to regulate the initiation and advance of cancer. The immune infiltration patterns of TME have been considered to impact the prognosis and immunotherapy sensitivity in Head and Neck squamous ...
Yinghe Ding +5 more
semanticscholar +1 more source
Immune Infiltration in Invasive Lobular Breast Cancer [PDF]
JNCI: Journal of the National Cancer Institute, 2018 Invasive lobular breast cancer (ILC) is the second most common histological subtype of breast cancer after invasive ductal cancer (IDC). Here, we aimed at evaluating the prevalence, levels, and composition of tumor-infiltrating lymphocytes (TILs) and their association with clinico-pathological and outcome variables in ILC, and to compare them with IDC ...
Desmedt, Christine +23 more
openaire +7 more sources
The Prognostic Value of GNG7 in Colorectal Cancer and Its Relationship With Immune Infiltration
Frontiers in Genetics, 2022 Background: G Protein Subunit Gamma 7 (GNG7) is an important gene that regulates cell proliferation and induces apoptosis. However, the correlation between GNG7 expression and immune infiltration as well as patient prognosis of colorectal cancer (CRC ...
Can Fang +3 more
doaj +1 more source
Frontiers in Immunology, 2023 Background Osteoarthritis (OA) is a degenerative disease closely related to aging. Nevertheless, the role and mechanisms of aging in osteoarthritis remain unclear.
Jiangfei Zhou +6 more
semanticscholar +1 more source
TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain [PDF]
, 2016 Background: The relationship between the brain and the immune system has become increasingly topical as, although it is immune-specialised, the CNS is not free from the influences of the immune system.
A Boivin +53 more
core +2 more sources
Nature Communications, 2023 Pediatric low-grade gliomas (pLGG) show heterogeneous responses to MAPK inhibitors (MAPKi) in clinical trials. Thus, more complex stratification biomarkers are needed to identify patients likely to benefit from MAPKi therapy.
Romain Sigaud +35 more
semanticscholar +1 more source
Aging, 2015 The past decade has witnessed a major revolution in cancer research. While malignancy was (and is) generally considered as a cell-autonomous genetic and epigenetic disease, it turned out that cancer has also an immunological connotation [1]. Only if the immune system fails to eliminate the (pre-)neoplastic cells cancer can emerge and progress.
Gautier, Stoll +2 more
openaire +2 more sources