Results 41 to 50 of about 2,585,977 (417)

Machine-Learning Algorithm-Based Prediction of Diagnostic Gene Biomarkers Related to Immune Infiltration in Patients With Chronic Obstructive Pulmonary Disease

Frontiers in Immunology, 2022
Objective This study aims to identify clinically relevant diagnostic biomarkers in chronic obstructive pulmonary disease (COPD) while exploring how immune cell infiltration contributes towards COPD pathogenesis.
Yuepeng Zhang, R. Xia, Mei-ling Lv, Zhiheng Li, Lingling Jin, Xueda Chen, Ya-Qin Han, C. Shi, Yanan Jiang, Shoude Jin   +9 more
semanticscholar   +1 more source

Identification and Verification of Immune-Related Gene Prognostic Signature Based on ssGSEA for Osteosarcoma

Frontiers in Oncology, 2020
Osteosarcoma is the most common malignant bone tumor in children and adolescence. Multiple immune-related genes have been reported in different cancers.
Bo Xiao, Bo Xiao, Liyan Liu, Liyan Liu, Aoyu Li, Aoyu Li, Cheng Xiang, Cheng Xiang, Pingxiao Wang, Pingxiao Wang, Hui Li, Hui Li, Tao Xiao, Tao Xiao   +13 more
doaj   +1 more source

Machine learning-based characterization of cuprotosis-related biomarkers and immune infiltration in Parkinson’s disease

Frontiers in Genetics, 2022
Background: Parkinson’s disease (PD) is a neurodegenerative disease commonly seen in the elderly. On the other hand, cuprotosis is a new copper-dependent type of cell death that can be observed in various diseases.
Songyun Zhao, Li Zhang, Wei-Fang Ji, Yachen Shi, Guichuan Lai, Hao Chi, Weiyi Huang, Chao Cheng   +7 more
semanticscholar   +1 more source

The Prognostic Value of GNG7 in Colorectal Cancer and Its Relationship With Immune Infiltration

Frontiers in Genetics, 2022
Background: G Protein Subunit Gamma 7 (GNG7) is an important gene that regulates cell proliferation and induces apoptosis. However, the correlation between GNG7 expression and immune infiltration as well as patient prognosis of colorectal cancer (CRC ...
Can Fang, Rulei Zhong, Chenyang Qiu, Bing-bing Zou   +3 more
doaj   +1 more source

Identification of immune infiltration and cuproptosis-related subgroups in Crohn’s disease

Frontiers in Immunology, 2022
Background Crohn’s disease (CD) is a type of heterogeneous, dysfunctional immune-mediated intestinal chronic and recurrent inflammation caused by a variety of etiologies.
Yifan Yuan, M. Fu, Na Li, Mei Ye
semanticscholar   +1 more source

Infiltration of tumor spheroids by activated immune cells

Physical Biology, 2022
Abstract Recent years have seen a tremendous growth of interest in understanding the role that the adaptive immune system could play in interdicting tumor progression. In this context, it has been shown that the density of adaptive immune cells inside a solid tumor serves as a favorable prognostic marker across different types of cancer.
Mrinmoy Mukherjee, Oleksandr Chepizhko, Maria Chiara Lionetti, Stefano Zapperi, Caterina A. M. La Porta, Herbert Levine   +5 more
openaire   +4 more sources

The Landscape of Immune Cells Infiltrating in Prostate Cancer [PDF]

Frontiers in Oncology, 2020
This study was to explore the infiltration pattern of immune cells in the prostate cancer (PCa) microenvironment and evaluate the possibility of specific infiltrating immune cells as potential prognostic biomarkers in PCa.Infiltrating percentage of 22 immune cells were extracted from 27 normalized datasets by CIBERSORT algorithm. Samples with CIBERSORT
Zhicong Wu, Zhicong Wu, Hua Chen, Wenyang Luo, Hanyun Zhang, Guihuan Li, Fangyin Zeng, Fan Deng   +7 more
openaire   +4 more sources

The immune phenotypes and different immune escape mechanisms in colorectal cancer

Frontiers in Immunology, 2022
The tumor microenvironment (TME) plays a crucial role in tumor progression and metastasis. However, the immune phenotypes of colorectal cancer (CRC) and the underlying immune escape mechanism have not been studied sufficiently.
Yihao Mao, Yuqiu Xu, Jiang Chang, Wenju Chang, Wenju Chang, Yang Lv, Peng Zheng, Zhiyuan Zhang, Zhiqiang Li, Qi Lin, Qi Lin, Wentao Tang, Wentao Tang, Dexiang Zhu, Dexiang Zhu, Meiling Ji, Meiling Ji, Guodong He, Guodong He, Qingyang Feng, Qingyang Feng, Jianmin Xu, Jianmin Xu   +22 more
doaj   +1 more source

Immune Infiltration Analysis with the CIBERSORT Method in Lung Cancer

Disease Markers, 2022
Background Immune infiltration of lung cancer (LC) is tightly related to clinical results. Nevertheless, past researches have not elucidated the diversities of functionally different cellular types making up the immunoresponse.
Meng Guan, Y. Jiao, Lili Zhou
semanticscholar   +1 more source

TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain [PDF]

, 2016
Background: The relationship between the brain and the immune system has become increasingly topical as, although it is immune-specialised, the CNS is not free from the influences of the immune system.
A Boivin, A Constant, A Walter, AD Bachstetter, Alison McColl, B Winner, BT Fife, C Callewaere, C D'Mello, C Gemma, CA Thomson, Carolyn A. Thomson, CP Marques, CS McKimmie, CT Ekdahl, D Michlmayr, D Michlmayr, EE Ubogu, G Banisadr, G Banisadr, Gerard J. Graham, JH Dufour, JL Teeling, Jonathan Cavanagh, JS Cameron, JS Snyder, JT Rogers, L Azzi, L Cartier, L Fits van der, Louis Nerurkar, M Baggiolini, M Udina, ML Monje, MM Lee, N Andrews, Q Liu, R Dantzer, R Deacon, R Krishnan, R Rola, RM Deacon, RM Ransohoff, S Baraldi, S Goethals, S Potvin, S Tyring, SM O'Brien, U Patel, U Puntener, W Huang da, W Huang da, W Rostene, WJ Karpus   +53 more
core   +2 more sources