Results 81 to 90 of about 2,585,977 (417)
Frontiers in Immunology, 2021 Intervertebral disc (IVD) degeneration and its inflammatory microenvironment ultimately led to discogenic pain, which is thought to originate in the nucleus pulposus (NP).
Linbang Wang +6 more
semanticscholar +1 more source
Perivascular adipose tissue inflammation in vascular disease [PDF]
, 2017 Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular ...
Guzik, Tomasz J., Nosalski, Ryszard
core +1 more source
A hybrid discrete-continuum modelling approach to explore the impact of T-cell infiltration on anti-tumour immune response [PDF]
arXiv, 2022 We present a spatial hybrid discrete-continuum modelling framework for the interaction dynamics between tumour cells and cytotoxic T cells, which play a pivotal role in the immune response against tumours. In this framework, tumour cells and T cells are modelled as individual agents while chemokines that drive the chemotactic movement of T cells ...
arxiv
Frontiers in Immunology, 2021 Background Overexpression of NPM1 can promote the growth and proliferation of various tumor cells. However, there are few studies on the comprehensive analysis of NPM1 in lung adenocarcinoma (LUAD). Methods TCGA and GEO data sets were used to analyze the
Xu-Sheng Liu +6 more
semanticscholar +1 more source
Frontiers in Oncology, 2021 Reports indicate that the use of anti-programmed cell death-1 (PD-1) and death ligand-1 (PD-L1) monoclonal antibodies for the treatment of patients diagnosed with melanoma has demonstrated promising efficacy.
Gang Li, Xuran Zhu, Chao Liu
doaj +1 more source
Frontiers in Genetics, 2022 Breast cancer is the malignant tumor with the highest incidence rate at present, and its incidence rate ranks first in the female population. COL11A1 is an important component of collagen XI and is considered to play an important role in a variety of ...
Q. Luo +5 more
semanticscholar +1 more source
Differential regulation of innate and adaptive immune responses in viral encephalitis. [PDF]
, 2004 Viral encephalitis is a global health concern. The ability of a virus to modulate the immune response can have a pivotal effect on the course of disease and the fate of the infected host. In this study, we sought to understand the immunological basis for
Buchmeier, Michael J +3 more
core +1 more source
Frontiers in Immunology, 2022 Immunotherapy, closely associated with immune infiltration and tumor mutation burden (TMB), is emerging as a promising strategy for treating tumors, but its low response rate in hepatocellular carcinoma (HCC) remains a major challenge. Herein, we applied
Yuanyuan Guo +14 more
doaj +1 more source
CRC-ICM: Colorectal Cancer Immune Cell Markers Pattern Dataset [PDF]
arXiv, 2023 Colorectal Cancer (CRC) is the second most common cause of cancer death in the world, ad can be identified by the location of the primary tumor in the large intestine: right and left colon, and rectum. Based on the location, CRC shows differences in chromosomal and molecular characteristics, microbiomes incidence, pathogenesis, and outcome. It has been
arxiv
Frontiers in Immunology, 2022 Background Pancreatic adenocarcinoma (PAAD) is a treatment-refractory cancer with poor prognosis. Accumulating evidence suggests that squalene epoxidase (SQLE) plays a pivotal role in the development and progression of several cancer types in humans ...
Weiqiang You +6 more
semanticscholar +1 more source