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A dual nature of γδ T cell immune memory responses [PDF]
eLifeImmune memory was considered for decades an exclusive hallmark of the adaptive immune response. However, recent studies have revealed that innate immune cells can also ‘recall’ information of a primary insult during infection or vaccination and deploy ...
Tsz Kin Suen +5 more
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Innate immune memory in cardiometabolic disease. [PDF]
Cardiovasc Res, 2023 Abstract Low-grade systemic inflammation is a key pathophysiological component of atherosclerotic cardiovascular disease (CVD), and long-term activation of myeloid cells is thought to be crucial for these effects. Obesity and associated metabolic complications including hyperglycaemia and dyslipoproteinaemia can induce long-lasting ...
Bahrar H +4 more
europepmc +4 more sources
Epigenetic remodeling in insect immune memory. [PDF]
Front ImmunolThe innate immune system of insects can respond more swiftly and efficiently to pathogens based on previous experience of encountering antigens. The understanding of molecular mechanisms governing immune priming, a form of immune memory in insects, including its transgenerational inheritance, remains elusive.
Mukherjee K, Dobrindt U.
europepmc +4 more sources
Development and function of protective and pathologic memory CD4 T cells [PDF]
, 2015 Immunological memory is one of the defining features of the adaptive immune system. As key orchestrators and mediators of immunity, CD4 T cells are central to the vast majority of adaptive immune responses.
Jaigirdar, Shafqat Ahrar +1 more
core +9 more sources
Immune memory: an evolutionary perspective [PDF]
Human Vaccines & Immunotherapeutics, 2021 The innate immune system, through pattern recognition receptors, intercepts any kind of pathogen and reacts through chemotactic, phagocyting, cytokines-secreting and cell-killing mechanisms in a very quick and effective way. Meanwhile, the adaptive immunity arm, through dendritic and T and B cells memory activation, is alerted and starts, more slowly ...
Beniamino Palmieri +2 more
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Modelling Immune Memory Development
Bulletin of Mathematical Biology, 2021 The cellular adaptive immune response to influenza has been analyzed through several recent mathematical models. In particular, Zarnitsyna et al. (Front Immunol 7:1-9, 2016) show how central memory CD8+ T cells reach a plateau after repeated infections, and analyze their role in the immune response to further challenges.
Pascucci E., Pugliese A.
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Innate immune memory, trained immunity and nomenclature clarification [PDF]
Nature Immunology, 2023 Contains fulltext : 295907.pdf (Publisher’s version ) (Open Access)
George Hajishengallis +2 more
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Frontiers in Cellular Neuroscience, 2023 Microglial cells are recognized as very dynamic brain cells, screening the environment and sensitive to signals from all other cell types in health and disease.
Miriam Corraliza-Gomez +8 more
doaj +1 more source
Nature Communications, 2023 A positron emission tomography (PET) tracer detecting α-synuclein pathology will improve the diagnosis, and ultimately the treatment of α-synuclein-related diseases.
Ruben Smith +25 more
doaj +1 more source
Frontiers in Immunology, 2021 Immunosenescence is a physiological process that is associated with changes in the immune system, particularly among CD8 T-cells. Recent studies have hypothesized that senescent CD8 T-cells are produced with chronologic age by chronic stimulation ...
Lauren Daniel +13 more
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