Results 11 to 20 of about 663,728 (297)

B-Cell Memory Responses to Variant Viral Antigens

open access: yesViruses, 2021
A central feature of vertebrate immune systems is the ability to form antigen-specific immune memory in response to microbial challenge and so provide protection against future infection.
Harry N White
doaj   +1 more source

Microbial-Driven Immunological Memory and Its Potential Role in Microbiome Editing for the Prevention of Colorectal Cancer

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Over the last several years, many advances have been made in understanding the role of bacteria in the pathogenesis of gastrointestinal cancers. Beginning with Helicobacter pylori being recognized as the first bacterial carcinogen and the causative agent
Laure Campillo-Gimenez   +12 more
doaj   +1 more source

Immunological Memory in Innate Immunity [PDF]

open access: yesJournal of Innate Immunity, 2013
‘trained immunity’. Trained immunity provides protection against reinfection in a T-/B-cell-independent manner, with nonspecific potentiation of inflammatory reactions and antimicrobial mechanisms playing a central role in these effects [4] . The current issue of the Journal of Innate Immunity presents a series of studies that shed additional light on ...
Netea, M.G., Netea, M.G.
openaire   +4 more sources

A Sustained Immune Response Supports Long-Term Antiviral Immune Priming in the Pacific Oyster, Crassostrea gigas

open access: yesmBio, 2020
Over the last decade, innate immune priming has been evidenced in many invertebrate phyla. If mechanistic models have been proposed, molecular studies aiming to substantiate these models have remained scarce.
Maxime Lafont   +12 more
doaj   +1 more source

CD4 memory has a hierarchical structure created by requirements for infection-derived signals at an effector checkpoint

open access: yesFrontiers in Immunology, 2023
Our recent studies reveal that the persistence, location, and amount of both antigen and signals that induce pathogen recognition responses determine the number of CD4 memory cells, the subsets that develop, their location, and hence their protective ...
Susan L. Swain
doaj   +1 more source

NK Cells and Immune “Memory” [PDF]

open access: yesThe Journal of Immunology, 2011
Abstract Immunological memory is a hallmark of the adaptive immune system. However, the ability to remember and respond more robustly against a second encounter with the same pathogen has been described in organisms lacking T and B cells.
Joseph C, Sun   +4 more
openaire   +2 more sources

T‐cell activation and immune memory enhancement induced by irreversible electroporation in pancreatic cancer

open access: yesClinical and Translational Medicine, 2020
Background Irreversible electroporation is shown to induce immune changes in pancreatic cancer while the histology evidences are still lacking.
Chaobin He   +4 more
doaj   +1 more source

DNA Methylation and Immune Memory Response [PDF]

open access: yesCells, 2021
The generation of memory is a cardinal feature of the adaptive immune response, involving different factors in a complex process of cellular differentiation. This process is essential for protecting the second encounter with pathogens and is the mechanism by which vaccines work.
Nathalia Noschang Mittelstaedt   +5 more
openaire   +3 more sources

Immunological memory ≠ protective immunity [PDF]

open access: yesCellular and Molecular Life Sciences, 2012
So-called 'immunological memory' is, in my view, a typical example where a field of enquiry, i.e. to understand long-term protection to survive reexposure to infection, has been overtaken by 'l'art pour l'art' of 'basic immunology'. The aim of this critical review is to point out some key differences between academic text book-defined immunological ...
openaire   +4 more sources

1IFN-α Modulates Memory Tfh Cells and Memory B Cells in Mice, Following Recombinant FMDV Adenoviral Challenge

open access: yesFrontiers in Immunology, 2020
Follicular helper T (Tfh) cells regulate high-affinity antibody production. Some findings have indicated that Tfh cells could be differentiated into memory cells. Here we have investigated the effects of IFN-α, as an adjuvant, on the generation of memory
Xiangguo Duan   +10 more
doaj   +1 more source

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