Results 131 to 140 of about 593,447 (356)

Table_1_Tumor Immune Microenvironment Related Gene-Based Model to Predict Prognosis and Response to Compounds in Ovarian Cancer.xls

, 2021
Jiang Yang (626469), Shasha Hong (4335931), Xiaoyi Zhang (577299), Jingchun Liu (306275), Ying Wang (11406), Zhi Wang (193655), Likun Gao (3836167), Li Hong (426614)   +7 more
openalex   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Cancer Niche as a Garbage Disposal Machine: Implications of TCM-Mediated Balance of Body-Disease for Treatment of Cancer. [PDF]

, 2019
Cancer epidemic led to worldwide to search for a new "game changer" concept to govern cancer research and cancer treatment. Western medicine-based cancer research has been extending the impasse without resolution in sigh for improving survival of ...
Lee, Katherine L, Li, Shengwen Calvin, Luo, Jane   +2 more
core  

An epithelial-mesenchymal transition-related long non-coding RNA signature to predict overall survival and immune microenvironment in kidney renal clear cell carcinoma

, 2021
Youpeng Zhang, Yongbiao Cheng, Sen Li, Ning Zhao, Zhaohui Zhu   +4 more
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Review for "The Tumor Immune Microenvironment and Its Implications for Clinical Outcome in Patients with Oropharyngeal Squamous Cell Carcinoma"

, 2020

openalex   +1 more source

Crosstalk between the tumor microenvironment and immune response in thyroid cancer [PDF]

, 2019
Chan Kwon Jung
openalex   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Targeting microglia-Th17 feed-forward loop to suppress autoimmune neuroinflammation

Journal of Neuroinflammation
Microglia and Th17 cells are the major immunopathogenic cells in multiple sclerosis and its animal model of immune aspects, experimental autoimmune encephalomyelitis (EAE).
Jun Xiao, Zihan Meng, Yao Lu, Zongchang Nie, Yujie Liu, Zhi Yao, Yingchi Zhang, Long Li   +7 more
doaj   +1 more source

Effects of Angelica polysaccharide on differentiation and function in M2 macrophages

陆军军医大学学报
Objective To investigate the effect of Angelica polysaccharide (APS) on the differentiation and function of M2 macrophages and underlying molecular mechanism.
ZHANG Ke, CUI Zhao, QIN Yahan
doaj   +1 more source