A little less aggregation a little more replication: Viral manipulation of stress granules
Viruses depend entirely on host machinery and therefore aim to conquer the host and defeat its defenses to co‐opt its resources for its own replication. Improved understanding of how viruses counteract host immune responses such as stress granule assembly, detailed here, will inform future antiviral therapeutic strategies.
Matthew J. Brownsword, Nicolas Locker
wiley +1 more source
Metformin Treatment and Immune Reconstitution in People With HIV and Type 2 Diabetes: A Matched Retrospective Study. [PDF]
Bäckdahl T+5 more
europepmc +1 more source
Genetic oscillators play crucial roles in development. The hairy/Enhancer of split gene family (Hes/her) undergo cell‐autonomous genetic oscillations to regulate the timing of vertebrate segmentation and neural cell proliferation and differentiation. mRNA stability and translation are tightly regulated to maintain oscillatory expression.
Monica C. Blatnik+2 more
wiley +1 more source
Establishment and evaluation of a predictive model for immune reconstitution in people living with HIV after antiretroviral therapy. [PDF]
Li N+10 more
europepmc +1 more source
Recurrence of Pneumocystis carinii pneumonia in an HIV‐infected patient: apparent selective immune reconstitution after initiation of antiretroviral therapy [PDF]
Kristina Crothers, Laurence Huang
openalex +1 more source
Enhanced Separation of Extracellular Vesicles Using Capillary Isotachophoresis With Spacer Compounds
ABSTRACT Extracellular vesicles (EVs) are pivotal in numerous physiological and pathological processes, such as immune responses, viral pathogenesis, pregnancy, cardiovascular diseases, and cancer progression. Their capacity to influence complex intracellular pathways highlights their therapeutic potential in addressing various conditions, including ...
Milan Pieter Paul de Putter+4 more
wiley +1 more source
Combined Sequential Antiretroviral Therapy-Induced Immune Reconstitution Bone Loss and Estrogen Deficiency Bone Loss Are Cumulative in Mice Models. [PDF]
Dabeer S+5 more
europepmc +1 more source
ABSTRACT This review provides an in‐depth exploration of capillary electrophoresis–mass spectrometry (CE–MS) in biomolecular research from 2020 to 2024. CE–MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites ...
Laura Pont+2 more
wiley +1 more source
Pure White Cell Aplasia, an Exceedingly Rare Complication of a Thymoma, and Immune Reconstitution Following Bone Marrow Recovery. [PDF]
George GV+4 more
europepmc +1 more source