Results 21 to 30 of about 75,454 (300)

Immune reconstitution inflammatory syndrome

Indian Journal of Dermatology, Venereology and Leprology, 2008
Immune reconstitution inflammatory syndrome (IRIS) is a paradoxical deterioration in clinical status in a patient on antiretroviral treatment (ART) despite satisfactory control of viral replication and improvement of CD4 count.To study development of IRIS as a part of ART.Hundred patients on antiretroviral treatment were studied prospectively in the ...
Sharma, Ajay, Makrandi, Smita, Modi, Megha, Sharma, Archana, Marfatia, Yogesh   +4 more
openaire   +3 more sources

Rapid CD4 decline prior to antiretroviral therapy predicts subsequent failure to reconstitute despite HIV viral suppression

Journal of Infection and Public Health, 2018
HIV-1 infection is characterized by loss of CD4 T cells, leading to immunodeficiency. Initiation of antiretroviral therapy (ART) results in suppression of the viral load and increased CD4 counts.
Majid Darraj, Leigh A. Shafer, Shanna Chan, Ken Kasper, Yoav Keynan   +4 more
doaj   +1 more source

Severe leukoencephalopathy with fulminant cerebral edema reflecting immune reconstitution inflammatory syndrome during HIV infection: a case report

Journal of Medical Case Reports, 2010
Introduction Immune reconstitution inflammatory syndrome is a well-known complication in HIV-infected patients after initiation of highly active antiretroviral therapy resulting in rapid CD4+ cell count recovery and suppression of viral load.
Niederstadt Thomas, Minnerup Jens, Reichelt Doris, Dziewas Rainer, Oelschlaeger Christian, Ringelstein Erich B, Husstedt Ingo W   +6 more
doaj   +1 more source

Epigenetic programming of T cells impacts immune reconstitution in hematopoietic stem cell transplant recipients

Blood Advances, 2018
: Immune reconstitution following hematopoietic stem cell transplantation (HSCT) is critical in preventing harmful sequelae in recipients with cytomegalovirus (CMV) infection.
Kristine Hardy, Corey Smith, Wen Juan Tu, Robert McCuaig, Archana Panikkar, Vijayendra Dasari, Fan Wu, Siok-Keen Tey, Geoffrey R. Hill, Rajiv Khanna, Sudha Rao   +10 more
doaj   +1 more source

Post-transplant cyclophosphamide alters immune signatures and leads to impaired T cell reconstitution in allogeneic hematopoietic stem cell transplant

Journal of Hematology & Oncology, 2022
Despite the increased usage of post-transplant cyclophosphamide (PTCy) in allogeneic hematopoietic stem cell transplantation (allo-HSCT), our knowledge of immune reconstitution post-allo-HSCT in the setting of PTCy is limited.
Chenchen Zhao, Matthew Bartock, Bei Jia, Neal Shah, David F. Claxton, Baldeep Wirk, Kevin L. Rakszawski, Myles S. Nickolich, Seema G. Naik, Witold B. Rybka, W Christopher C. Ehmann, Raymond J. Hohl, Jessica Valentin, Michelle Bernas-Peterson, Emily M. Gerber, Michele Zimmerman, Joseph A. Mierski, Shin Mineishi, Hong Zheng   +18 more
doaj   +1 more source

Thymic involution and immune reconstitution [PDF]

Trends in Immunology, 2009
Chronic thymus involution associated with aging results in less efficient T-cell development and decreased emigration of naïve T cells to the periphery. Thymic decline in the aged is linked to increased morbidity and mortality in a wide range of clinical settings.
Heather E, Lynch, Gabrielle L, Goldberg, Ann, Chidgey, Marcel R M, Van den Brink, Richard, Boyd, Gregory D, Sempowski   +5 more
openaire   +2 more sources

Mass Cytometry for the Assessment of Immune Reconstitution After Hematopoietic Stem Cell Transplantation

Frontiers in Immunology, 2018
Mass cytometry, or Cytometry by Time-Of-Flight, is a powerful new platform for high-dimensional single-cell analysis of the immune system. It enables the simultaneous measurement of over 40 markers on individual cells through the use of monoclonal ...
Lauren Stern, Lauren Stern, Lauren Stern, Helen McGuire, Helen McGuire, Helen McGuire, Helen McGuire, Selmir Avdic, Selmir Avdic, Selmir Avdic, Simone Rizzetto, Barbara Fazekas de St Groth, Barbara Fazekas de St Groth, Barbara Fazekas de St Groth, Barbara Fazekas de St Groth, Fabio Luciani, Barry Slobedman, Barry Slobedman, Barry Slobedman, Emily Blyth, Emily Blyth, Emily Blyth, Emily Blyth   +22 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Demodicosis revealing an HIV infection

New Microbes and New Infections, 2019
We report an observation of facial and upper limb demodicosis, revealing a human immunodeficiency virus infection. After an initial improvement with metronidazole, worsening of skin lesions related to immune reconstitution inflammatory syndrome was ...
W. Hachfi, D. Slama, N. Ben Lasfar, K. Mnif, F. Bellazreg, A. Fathallah, A. Letaief   +6 more
doaj   +1 more source

A Severe Case of Molluscum Contagiosum Immune Reconstitution Inflammatory Syndrome in a Patient with Human Immunodeficiency Virus

European Journal of Case Reports in Internal Medicine, 2022
Paradoxical immune reconstitution inflammatory syndrome (IRIS) in human immunodeficiency virus (HIV)-positive patients initiating antiretroviral treatment (ART) is caused by restored immunity to specific antigens, resulting in worsening of a pre-existing
Nida Siddiqui, Brett Stephen Mansfield, Nine-Paula Olmesdahl, Peter Swart, Jeremy Nel   +4 more
doaj   +1 more source