Results 201 to 210 of about 78,926 (342)

Phenotypic profile of Mycobacterium tuberculosis -specific CD4 T cell responses in HIV-positive patients who develop Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome [PDF]

open access: gold, 2022
Raymond M Moseki   +7 more
openalex   +1 more source

Negative Pressure Wound Therapy in an Immunocompromised Child: A Case Report From a Resource‐Limited Setting in Ghana

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT An 8‐year‐old immunocompromised girl with a large septic wound on the left thigh was admitted to the facility after the failure of home treatment by the family. The child was generally stable aside from the difficulty in walking on the left leg.
Matilda Mawusi Kodjo   +5 more
wiley   +1 more source

Mycobacterial Antigen Driven Activation of CD14++CD16- Monocytes Is a Predictor of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome. [PDF]

open access: yes, 2014
Anbalagan, S   +18 more
core   +1 more source

Immune reconstitution inflammatory syndrome and human immunodeficiency virus infection [PDF]

open access: bronze, 2020
Seng Wee Cheo   +5 more
openalex   +1 more source

Life‐Threatening Agranulocytosis Induced by Sinomenine Hydrochloride in Chronic Kidney Disease: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Sinomenine, derived from Sinomenium acutum, is widely used in inflammatory diseases. However, its risk of inducing agranulocytosis is not widely appreciated. We report a life‐threatening case in a 40‐year‐old woman with chronic kidney disease (CKD; baseline estimated glomerular filtration rate [eGFR] as low as 36 mL/min/1.73 m2) who developed ...
Ping Xin, Ruoyan Liu, Yu Zhang, Bin Fu
wiley   +1 more source

Foundational Principles for the Quantitative Translation of T‐Cell Therapeutics for Hematologic Malignancies and Immunology

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 33-45, January 2026.
T‐cell engaging antibodies (TCEs) and chimeric antigen receptor (CAR) T cells (CAR‐T cells) are among precision medicine therapies that have revolutionized the treatment of hematologic cancers. Their success in oncology has piqued interest in translating this promise into additional indications, such as autoimmune disorders.
Peter Ashcroft   +6 more
wiley   +1 more source

Oral Delivery of R‐spondin1‐Loaded Small Extracellular Vesicles Activates WNT Signalling Pathway to Accelerate Intestinal Injury Repair and Reverse Ageing

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 1, January 2026.
Yang et al. demonstrated that HSPG mediate the loading of active R‐spondin1 protein onto the surface of small extracellular vesicles (evRSPO1). evRSPO1 induced WNT/β‐catenin activity in intestinal organoids and tissues, thereby regulating intestinal stem cells proliferation.
Lingyan Yang   +13 more
wiley   +1 more source

Organoids in Cancer Research and Regenerative Medicine: Current Status, Challenges, and Future Prospects

open access: yesMedComm, Volume 7, Issue 1, January 2026.
The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li   +5 more
wiley   +1 more source

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