Results 211 to 220 of about 78,926 (342)

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

Medicine Bulletin, Volume 2, Issue 1, Page 61-93, January 2026.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Thoracic manifestations of paradoxical immune reconstitution inflammatory syndrome during or after antituberculous therapy in HIV-negative patients

, 2015
Prapaporn Pornsuriyasak, Thitiporn Suwatanapongched   +1 more
openalex   +1 more source

Cellulitis Revealing a Cryptococcosis-Related Immune Reconstitution Inflammatory Syndrome in a Renal Allograft Recipient [PDF]

, 2007
Fanny Lanternier, Marie‐Olivia Chandesris, S. Poirée, M.-E. Bougnoux, F. Méchaï, Marie‐France Mamzer, Jean Paul Viard, Louise Galmiche, Marc Lecuit, Olivier Lortholary   +9 more
openalex   +1 more source

Regulatory T Cells and Nanomaterials: Dual Perspectives in Therapeutics and Immunomodulation

Small Science, Volume 6, Issue 1, January 2026.
Tregs control immune tolerance but can also enable tumor escape. Nanomaterials can now expand or stabilize Tregs to treat autoimmunity and support transplantation or conversely disrupt tumor Tregs to boost antitumor immunity. We also discuss unintended Treg modulation by nanoparticles, safety and manufacturing challenges, and future translational ...
Yiyin Chen, Haibo Huang, Xiang Wang, Xinghao Yu, Ziyan Huang, Zhou Jin, Chen Chen, Yan Chen, Bruce R. Blazar, Yang Xu, Yunjie Lu   +10 more
wiley   +1 more source

A severe case of buruli ulcer disease with pleural effusions. [PDF]

, 2014
Abass, MK, Abotsi, J, Asiedu, K, Frimpong, M, Paintsil, A, Phillips, RO, Sarfo, FS, Thompson, W, Wansbrough-Jones, MH   +8 more
core   +2 more sources

Immune Reconstitution Inflammatory Syndrome – Kochs

, 2015
Iosr Journals, Nageswaramma Siddabathuni, Swarna K Gunupudi, Sowmya Srirama   +3 more
openalex   +1 more source

Betulinic Acid Eradicates Implant‐Associated Infections by Disrupting the S. aureus Biofilm Matrix and Potentiating Host Immune Clearance

Microbial Biotechnology, Volume 19, Issue 1, January 2026.
Betulinic acid reduces infection by Staphylococcus aureus biofilms on implants by inhibiting their formation and adhesion, decreasing EPS and eDNA formation and enhancing immune clearance. Simultaneously, it reduces skin tissue inflammation, enhances type I collagen production, and promotes wound healing.
Dongbin Guo, Ye Tao, Luanbiao Sun, Xinyao Liu, Yuan Gao, Peitong Jiang, Han Gao, Bingmei Wang, Li Wang   +8 more
wiley   +1 more source

Humanized Mouse Models as a Cellular Platform for Investigating Immune‐Hormonal Crosstalk and Therapeutic Strategies in Menopause

Aging Cell, Volume 25, Issue 1, January 2026.
Humanized mice offer new insight into immune‐hormonal changes during menopause. Traditional models lack accuracy in replicating human menopause physiology. Functional foods may ease symptoms but need testing in human‐relevant systems. Combining humanized mice with diet research can improve women's health outcomes.
Nisansala Chandimali, Jaehoon Bae, Sun Hee Cheong, Seon Gyeong Bak, Yeon‐Yong Kim, Ji‐Su Kim, Seung‐Jae Lee   +6 more
wiley   +1 more source

Tuberculosis-associated immune reconstitution inflammatory syndrome in a non-immunocompromised patient. [PDF]

Breathe (Sheff)
Angelopoulos V, Papanikolaou A, Chronis C, Kyriakopoulos C, Ladias A, Assioura A, Gogali A, Kostikas K, Salla E.   +8 more
europepmc   +1 more source

FKBP5 Mediates Alveolar Fibroblast Necroptosis During Acute Respiratory Distress Syndrome

Cell Proliferation, Volume 59, Issue 1, January 2026.
Structure diagram of alveolar fibroblast activation in septic ARDS model. FKBP5‐mediated alveolar fibroblast necroptosis, leading to the activation of NF‐κB signalling and the secretion of cytokines and the recruitment of neutrophils, and further orchestrating the inflammatory environment of the alveolar epithelia in septic ARDS.
Dong Zhang, Wei Liu, Ting Sun, Yangyang Xiao, Qiuwen Chen, Xiao Huang, Xiaozhi Wang, Qian Qi, Hao Wang, Tao Wang   +9 more
wiley   +1 more source