Results 91 to 100 of about 288,801 (335)

Serum antibodies from Parkinson's disease patients react with neuronal membrane proteins from a mouse dopaminergic cell line and affect its dopamine expression

Journal of Neuroinflammation, 2006
Evidence exists suggesting that the immune system may contribute to the severity of idiopathic Parkinson's disease (IPD). The data presented here demonstrates that antibodies in the sera of patients with IPD have increased binding affinity to ...
Seegal Richard F, Factor Stewart A, Mondal Tapan, Huber Victor C, Lawrence David A   +4 more
doaj   +1 more source

Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex [PDF]

, 2017
Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, and developing a prophylactic vaccine is of high priority to public health.
Adler, Stuart P., An, Zhiqiang, DePhillips, Pete A., Freed, Daniel C., Fu, Tong-Ming, Ha, Sha, Hamm, Melissa, Li, Fengsheng, Loughney, John W., McLellan, Jason S., McVoy, Michael A., Nickle, David C., Rustandi, Richard R., Tang, Aimin, Troutman, Matthew C., Vlasak, Josef, Wang, Dai, Wang, I-Ming, Zhang, Ningyan, Zhu, Hua   +19 more
core   +3 more sources

Flocculation reactions with hemolytic immune sera.

Experimental Biology and Medicine, 1924
As mentioned in the proceedings of the last meeting of this Society, the hemolytic action of the immune sera prepared by injection of alcoholic blood extracts is inhibited by the addition of these same extracts. In analogy to the Forssman heterogenetic antibodies (Sordelli and Pico, Sachs and Guth) these sera were found to give a very distinct ...
J. V. D. Scheer, K. Landsteiner
openaire   +2 more sources

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Idiotypes of anti-Ia antibodies. I. Expression of the 14-4-4S idiotype in humoral immune responses. [PDF]

, 1981
The idiotype of a mouse monoclonal anti-I-E antibody, 14-4-4S, has been studied using a heterologous anti-idiotypic reagent. This antibody recognizes Ia.
Bluestone, JA, Epstein, SL, Ozato, K, Sachs, DH   +3 more
core  

Cytokine expression in malaria-infected non-human primate placentas [PDF]

, 2012
Malaria parasites are known to mediate the induction of inflammatory immune responses at the maternal-foetal interface during placental malaria (PM) leading to adverse consequences like pre-term deliveries and abortions.
Barasa, M., Barasa, M. B. O., Gicheru, M. M., Kagasi, E. A., Namulanda, F. B. M., Ng'ang'a, Z. W., Okoth, J. M., Ozwara, S. H., Sowayi, G. A.   +8 more
core   +4 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Characteristic features of the SERA multigene family in the malaria parasite

Parasites & Vectors, 2020
Serine repeat antigen (SERA) is conserved among species of the genus Plasmodium. Sera genes form a multigene family and are generally tandemly clustered on a single chromosome. Although all Plasmodium species encode multiple sera genes, the number varies
Nobuko Arisue, Nirianne M. Q. Palacpac, Takahiro Tougan, Toshihiro Horii   +3 more
doaj   +1 more source

γδ T cells affect IL-4 production and B-cell tolerance [PDF]

, 2014
γδ T cells can influence specific antibody responses. Here, we report that mice deficient in individual γδ T-cell subsets have altered levels of serum antibodies, including all major subclasses, sometimes regardless of the presence of αβ T cells.
Andrew Getahun, Cohen, Finkelman, Gerber, Greg A. Kirchenbaum, Hidaka, Hirose, Hua Huang, Izui, John C. Cambier, Koichi Ikuta, Kubo, Lawrence J. Wysocki, M. Kemal Aydintug, Rebecca L. O’Brien, Ryan A. Heiser, Simon R. Carding, Sperling, Sunaga, Tamara L. Casper, Thiago O. Detanico, Willi K. Born, Yafei Huang   +22 more
core   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source