Results 31 to 40 of about 84,619 (287)

Cross-Protective Immunity against Heterologous Streptococcus pneumoniae [PDF]

Infection and Immunity, 2012
Chimalapati et al. recently reported that infection with conditionally virulent Streptococcus pneumoniae Δ pab strains (containing a deletion of the gene encoding para -aminobenzoic acid synthetase) induced an effective antibody response to conserved protein antigens of S. pneumoniae ([1][1]).
Leen, Moens, Greet, Wuyts, Jan, Verhaegen, Xavier, Bossuyt   +3 more
openaire   +2 more sources

In-depth analysis of T cell immunity and antibody responses in heterologous prime-boost-boost vaccine regimens against SARS-CoV-2 and Omicron variant

Frontiers in Immunology, 2022
With the emergence of novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Variants of Concern (VOCs), vaccination studies that elucidate the efficiency and effectiveness of a vaccination campaign are critical to assess the durability and ...
Natalie Heinen, Corinna Sophie Marheinecke, Clara Bessen, Arturo Blazquez-Navarro, Arturo Blazquez-Navarro, Toralf Roch, Toralf Roch, Ulrik Stervbo, Moritz Anft, Carlos Plaza-Sirvent, Sandra Busse, Mara Klöhn, Jil Schrader, Elena Vidal Blanco, Doris Urlaub, Carsten Watzl, Markus Hoffmann, Stefan Pöhlmann, Matthias Tenbusch, Eike Steinmann, Daniel Todt, Daniel Todt, Carsten Hagenbeck, Gert Zimmer, Gert Zimmer, Wolfgang Ekkehard Schmidt, Daniel Robert Quast, Nina Babel, Nina Babel, Ingo Schmitz, Stephanie Pfänder   +30 more
doaj   +1 more source

Defective interfering virus protects elderly mice from influenza [PDF]

, 2011
Background: We have identified and characterised a defective-interfering (DI) influenza A virus particles containing a highly deleted segment 1 RNA that has broad-spectrum antiviral activity.
Scott, P. D. (Paul D.), Meng, Bo, Marriott, Anthony C., Easton, A. J. (Andrew J.), Dimmock, N. J.   +4 more
core   +3 more sources

Pathogenic epitopes, heterologous immunity and vaccine design [PDF]

Nature Reviews Microbiology, 2007
Substantial research has been directed towards the development of a new generation of vaccines that are based on the inclusion of immunogenic epitopes in recombinant vectors. Here we examine the evidence that under certain conditions immunogenic epitopes can do more harm than good and might therefore be considered pathogenic.
Welsh, Raymond M., Fujinami, Robert S.
openaire   +2 more sources

Heterologous prime-boost vaccination with H3N2 influenza viruses of swine favors cross-clade antibody responses and protection [PDF]

, 2017
The emergence of multiple novel lineages of H1 and H3 influenza A viruses in swine has confounded control by inactivated vaccines. Because of substantial genetic and geographic heterogeneity among circulating swine influenza viruses, one vaccine strain ...
Claes, Gerwin, Cox, Eric, Krammer, Florian, Mancera Gracia, José Carlos, Qiu, Yu, Sys, Lieve, Trus, Ivan, Van Reeth, Kristien, Versnaeyen, Han   +8 more
core   +2 more sources

Heterologous Immunity: Role in Natural and Vaccine-Induced Resistance to Infections

Frontiers in Immunology, 2019
The central paradigm of vaccination is to generate resistance to infection by a specific pathogen when the vacinee is re-exposed to that pathogen. This paradigm is based on two fundamental characteristics of the adaptive immune system, specificity and ...
Babita Agrawal
doaj   +1 more source

Cross protection to SARS-CoV-2 variants in hamsters with naturally-acquired immunity

Virology Journal, 2023
Since SARS-CoV-2 was first reported in late 2019, multiple variations of the original virus have emerged. Each variant harbors accumulations of mutations, particularly within the spike glycoprotein, that are associated with increased viral ...
Saina Beitari, Diana Duque, Jegarubee Bavananthasivam, Melissa Hewitt, Jagdeep K. Sandhu, Ita Hadžisejdić, Anh Tran   +6 more
doaj   +1 more source

Protection of hybrid immunity against SARS-CoV-2 reinfection and severe COVID-19 during periods of Omicron variant predominance in Mexico

Frontiers in Public Health, 2023
BackgroundWith the widespread transmission of the Omicron SARS-CoV-2 variant, reinfections have become increasingly common. Here, we explored the role of immunity, primary infection severity, and variant predominance in the risk of reinfection and severe
José Antonio Montes-González, Christian Arturo Zaragoza-Jiménez, Neftali Eduardo Antonio-Villa, Carlos A. Fermín-Martínez, Carlos A. Fermín-Martínez, Daniel Ramírez-García, Arsenio Vargas-Vázquez, Rosaura Idania Gutiérrez-Vargas, Gabriel García-Rodríguez, Hugo López-Gatell, Sergio Iván Valdés-Ferrer, Omar Yaxmehen Bello-Chavolla   +11 more
doaj   +1 more source

Heterologous immunity meets tissue-specific training [PDF]

Nature Reviews Immunology, 2016
Tracy Hussell describes a 2003 study by Chen et al. that pioneered the concept of heterologous immunity.
openaire   +2 more sources

Immune complex glomerulonephritis is induced in rats immunized with heterologous myeloperoxidase [PDF]

Clinical and Experimental Immunology, 1994
SUMMARY Anti-neutrophil cytoplasmic antibodies (ANCA), including anti-myeloperoxidase (MPO) antibodies, are associated with pauci-immune necrotizing small vessel vasculitis or glomerulonephritis, 1n order to substantiate a pathogenic role for ANCA, an animal model of pauci-immune ANCA-induced glomerulonephritis or vasculitis is required.
J J, Yang, J C, Jennette, R J, Falk
openaire   +2 more sources