Results 31 to 40 of about 49,620 (199)

A high force of Plasmodium vivax blood-stage infection drives the rapid acquisition of immunity in Papua New Guinean children [PDF]

, 2013
When both parasite species are co-endemic, Plasmodium vivax incidence peaks in younger children compared to P. falciparum. To identify differences in the number of blood stage infections of these species and its potential link to acquisition of immunity,
Speed, Terence P., Ingrid Felger (92160), Kiniboro, B, Mueller Ivo, Kathryn L Colborn, Koepfli, Cristian, Terence P. Speed (132229), Speed Terence P., Koepfli, C, Cristian Koepfli, Felger Ingrid, Felger, Ingrid, Kiniboro, Benson, Terence P Speed, Kiniboro Benson, Ingrid Felger, Peter M. Siba (136849), Ivo Mueller (46609), Felger, I, Enmoore Lin, Lin Enmoore, Mueller, Ivo, Benson Kiniboro (191309), Ivo Mueller, Enmoore Lin (137888), Koepfli Cristian, Lin, Enmoore, Lin, E, Kathryn L. Colborn (454997), Colborn Kathryn L., Siba Peter M., Speed, TP, Mueller, I, Colborn, Kathryn L., Siba, PM, Siba, Peter M., Colborn, KL, Peter M Siba, Cristian Koepfli (191306), Benson Kiniboro   +39 more
core   +1 more source

Immunization with an autotransporter protein of Orientia tsutsugamushi provides protective immunity against scrub typhus. [PDF]

PLoS Neglected Tropical Diseases, 2015
BACKGROUND:Scrub typhus is an acute febrile disease caused by Orientia tsutsugamushi infection. Recently, the rapid increase of scrub typhus incidence in several countries within the endemic region has become a serious public health issue.
Na-Young Ha, Prashant Sharma, Gwanghun Kim, Yuri Kim, Chan-Ki Min, Myung-Sik Choi, Ik-Sang Kim, Nam-Hyuk Cho   +7 more
doaj   +1 more source

Heterologous immunity in the absence of variant-specific antibodies after exposure to subpatent infection with blood-stage malaria [PDF]

, 2005
We examined immunity induced by subpatent blood-stage malaria (undetectable by microscopy) using the rodent malaria parasite, Plasmodium chabaudi chabaudi, postulating that limited infection may allow expansion of antigen-specific T cells that are ...
Elliott, Salenna R., Kuns, Rachel D., Good, Michael F.   +2 more
core   +1 more source

Trained-immunity and cross-reactivity for protection: insights from the coronavirus disease 2019 and monkeypox emergencies for vaccine development

Exploration of Immunology, 2023
The emergence and re-emergence of pathogens is a public-health concern, which has become more evident after the coronavirus disease 2019 (COVID-19) pandemic and the monkeypox outbreaks in early 2022.
Amanda Izeli Portilho, Elizabeth De Gaspari   +1 more
doaj   +1 more source

Immune complex glomerulonephritis is induced in rats immunized with heterologous myeloperoxidase [PDF]

Clinical and Experimental Immunology, 1994
SUMMARY Anti-neutrophil cytoplasmic antibodies (ANCA), including anti-myeloperoxidase (MPO) antibodies, are associated with pauci-immune necrotizing small vessel vasculitis or glomerulonephritis, 1n order to substantiate a pathogenic role for ANCA, an animal model of pauci-immune ANCA-induced glomerulonephritis or vasculitis is required.
J J, Yang, J C, Jennette, R J, Falk
openaire   +2 more sources

Heterologous autoimmunity and prokaryotic immune defense [PDF]

, 2021
Some prokaryotes possess CRISPR-Cas systems that provide adaptive immunity to viruses guided by DNA segments called spacers acquired from invading phage. However, the patchy incidence and limited memory breadth of CRISPR-Cas systems suggest that their fitness benefits are offset by costs.
Hanrong Chen, Andreas Mayer, Vijay Balasubramanian   +2 more
openaire   +2 more sources

Heterologous Immunity and Persistent Murine Cytomegalovirus Infection [PDF]

Journal of Virology, 2017
ABSTRACT One's history of infections can affect the immune response to unrelated pathogens and influence disease outcome through the process of heterologous immunity. This can occur after acute viral infections, such as infections with lymphocytic choriomeningitis virus (LCMV) and vaccinia virus, where the pathogens are cleared ...
Jenny W, Che, Keith A, Daniels, Liisa K, Selin, Raymond M, Welsh   +3 more
openaire   +2 more sources

Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies

, 2020
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.

core   +1 more source

Heterologous Immunity: Role in Natural and Vaccine-Induced Resistance to Infections

Frontiers in Immunology, 2019
The central paradigm of vaccination is to generate resistance to infection by a specific pathogen when the vacinee is re-exposed to that pathogen. This paradigm is based on two fundamental characteristics of the adaptive immune system, specificity and ...
Babita Agrawal
doaj   +1 more source

Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells [PDF]

, 2007
Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens
Owain R Millington, Bernd H. Zinselmeyer, Zinselmeyer Bernd H, Brewer James M, Paul Garside, Rush, Catherine M., Rush, C.M., Owain R. Millington, Millington, O.R., Vivienne B Gibson, Catherine M. Rush, Bernd H Zinselmeyer, Rush, C., R. Stephen Phillips, Gibson, V.B., Vivienne B. Gibson, Phillips, R.S., R Stephen Phillips, Catherine M Rush, Zinselmeyer, B.H., Millington, Owain R., Brewer, James M., Gibson Vivienne B, Millington Owain R, Brewer, J.M., Gibson, Vivienne B., Phillips R. Stephen, Garside Paul, Rush Catherine M, Phillips, R. Stephen, Zinselmeyer, Bernd H., Garside, P., James M. Brewer, Garside, Paul, James M Brewer   +34 more
core   +1 more source