Heterologous immunity in the absence of variant-specific antibodies after exposure to subpatent infection with blood-stage malaria [PDF]
, 2005 We examined immunity induced by subpatent blood-stage malaria (undetectable by microscopy) using the rodent malaria parasite, Plasmodium chabaudi chabaudi, postulating that limited infection may allow expansion of antigen-specific T cells that are ...
Elliott, Salenna R. +2 more
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SPECIFIC HETEROLOGOUS ENHANCEMENT OF IMMUNE RESPONSES [PDF]
The Journal of Experimental Medicine, 1973 The mixing of two histoincompatible human lymphocyte cell lines generated the release of a soluble factor which was capable of nonspecifically enhancing the in vitro immune response of normal mouse spleen cells against sheep erythrocytes. When active supernates were subjected to exclusion chromatography on Sephadex G-150 and BioGel P-150, the active ...
A S, Rubin, A B, MacDonald, A H, Coons
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Suppression of adaptive immunity to heterologous antigens during plasmodium infection through hemozoin-induced failure of dendritic cell function [PDF]
, 2006 Dendritic cells (DCs) are central to the initiation and regulation of the adaptive immune response during infection. Modulation of DC function may therefore allow evasion of the immune system by pathogens.
Di Lorenzo, Caterina +4 more
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Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies
, 2020 This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.
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Heterologous Immunity: Role in Natural and Vaccine-Induced Resistance to Infections
Frontiers in Immunology, 2019 The central paradigm of vaccination is to generate resistance to infection by a specific pathogen when the vacinee is re-exposed to that pathogen. This paradigm is based on two fundamental characteristics of the adaptive immune system, specificity and ...
Babita Agrawal
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Immune complex glomerulonephritis is induced in rats immunized with heterologous myeloperoxidase [PDF]
Clinical and Experimental Immunology, 1994 SUMMARY Anti-neutrophil cytoplasmic antibodies (ANCA), including anti-myeloperoxidase (MPO) antibodies, are associated with pauci-immune necrotizing small vessel vasculitis or glomerulonephritis, 1n order to substantiate a pathogenic role for ANCA, an animal model of pauci-immune ANCA-induced glomerulonephritis or vasculitis is required.
J J, Yang, J C, Jennette, R J, Falk
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Cross protection to SARS-CoV-2 variants in hamsters with naturally-acquired immunity
Virology Journal, 2023 Since SARS-CoV-2 was first reported in late 2019, multiple variations of the original virus have emerged. Each variant harbors accumulations of mutations, particularly within the spike glycoprotein, that are associated with increased viral ...
Saina Beitari +6 more
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Frontiers in Public Health, 2023 BackgroundWith the widespread transmission of the Omicron SARS-CoV-2 variant, reinfections have become increasingly common. Here, we explored the role of immunity, primary infection severity, and variant predominance in the risk of reinfection and severe
José Antonio Montes-González +11 more
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Heterologous Immunity and Persistent Murine Cytomegalovirus Infection [PDF]
Journal of Virology, 2017 ABSTRACT One's history of infections can affect the immune response to unrelated pathogens and influence disease outcome through the process of heterologous immunity. This can occur after acute viral infections, such as infections with lymphocytic choriomeningitis virus (LCMV) and vaccinia virus, where the pathogens are cleared ...
Jenny W, Che +3 more
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Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells [PDF]
, 2007 Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens
Owain R Millington +34 more
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