Results 81 to 90 of about 14,479 (218)

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Recent Advances in Zirconium-89 Chelator Development

Molecules, 2018
The interest in zirconium-89 (89Zr) as a positron-emitting radionuclide has grown considerably over the last decade due to its standardized production, long half-life of 78.2 h, favorable decay characteristics for positron emission tomography (PET ...
Nikunj B. Bhatt, Darpan N. Pandya, Thaddeus J. Wadas   +2 more
doaj   +1 more source

Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo [PDF]

, 2017
This is the final published versionAvailable from Ivyspring International Publisher via the DOI in this recordInvasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of hematological malignancy and bone marrow transplant patients caused
Boschetti, F, Davies, G, Denat, F, Dubois, A, Eichner, M, Foslet, J, Gunzer, M, Hasenberg, M, Jensen, M, Maurer, A, Pichler, BJ, Rolle, A-M, Ryder, LS, Schibli, R, Schillinger, C, Solouk-Saran, D, Spycher, PR, Thornton, CR, Weski, J, Wiehr, S   +19 more
core   +3 more sources

MRI for Lung Cancer Management: Any Closer to Clinical Application?

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Management of lung cancer (LC) encompasses screening, diagnosis, staging, radiotherapy planning and guidance, therapy monitoring and surveillance. Across these domains, magnetic resonance imaging (MRI) offers a range of morphological and functional imaging capabilities—including diffusion‐weighted imaging (DWI), dynamic contrast‐enhanced (DCE)
Juergen Biederer, Liisa L. Bergmann, Jeanne B. Ackman, Bruno Hochhegger, Lea Azour, Simon M. F. Triphan, Julien Dinkel, Yoshiharu Ohno, Yoshiyuki Ozawa, Edwin J. R. van Beek, Lena Wucherpfennig   +10 more
wiley   +1 more source

Excitation functions for (p,x) reactions of niobium in the energy range of E$_{\text{p}}$ = 40-90 MeV [PDF]

, 2018
A stack of thin Nb foils was irradiated with the 100 MeV proton beam at Los Alamos National Laboratory's Isotope Production Facility, to investigate the $^{93}$Nb(p,4n)$^{90}$Mo nuclear reaction as a monitor for intermediate energy proton experiments and
Bernstein, Lee A., Birnbaum, Eva R., Engle, Jonathan W., Graves, Stephen A., Kawano, Toshihiko, Lewis, Amanda M., Nortier, Francois M., Voyles, Andrew S.   +7 more
core   +2 more sources

Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP

The Laryngoscope, EarlyView.
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best, Aaron D. Friedman, Clark A. Rosen, Robert T. Sataloff, Laura A. Matrka, H. Steven Sims, David E. Rosow, Nabil F. Saba, David G. Lott, Adam M. Klein, Ted Mau, Milan R. Amin, Kathryn A. Wikenheiser‐Brokamp, Scott M. Norberg, Kim McClellan, Geoffrey D. Young, Clint T. Allen, on behalf of the Recurrent Respiratory Papillomatosis Foundation   +17 more
wiley   +1 more source

Potential role of 124I-girentuximab in the presurgical diagnosis of clear-cell renal cell cancer

Biologics: Targets & Therapy, 2012
Marc C Smaldone,1 David YT Chen,1 Jian Q Yu,2 Elizabeth R Plimack31Division of Urologic Oncology, 2Department of Diagnostic Imaging, 3Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USAAbstract: Renal cell carcinoma (RCC) is a ...
Plimack ER, Yu JQ, Chen DY, Smaldone MC
doaj  

Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers [PDF]

, 2017
Blockade of the inhibitory PD-1/PD-L1 immune checkpoint axis is a promising cancer treatment. Nonetheless, a significant number of patients and malignancies do not respond to this therapy.
Breckpot, K, Broos, K, Devoogdt, N, Escors, D, Keyaerts, M, Lecocq, Q, Liston, A, Nguyen, T, Raes, G, Renmans, D   +9 more
core   +2 more sources

Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements

Molecular Carcinogenesis, EarlyView.
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia, Ayman J. Oweida, Houda Bahig, Daniel Taussky   +3 more
wiley   +1 more source

Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes, Daniel G. Di Luca, Connie Marras, Erik Boot, Ryan K.C. Yuen, Anthony E. Lang, Anne S. Bassett   +6 more
wiley   +1 more source