Results 101 to 110 of about 14,479 (218)

Quantification of immuno-PET imaging in cancer [PDF]

As immuno-PET demonstrates significant potential in the development of mAb-based therapy, valid quantification is crucial in the interpretation of immuno-PET scans.
Wijngaarden, Jessica Eline
core   +1 more source

Availability and Costs of Allergic Rhinitis Treatments Across the World: A Survey of ARIA Experts

Allergy, EarlyView.
We surveyed experts of the ARIA group on the costs of medications for allergic rhinitis in the respective countries. Overall, oral antihistamines are the cheapest medications while fixed combinations of antihistamines + corticosteroids are the most expensive.
Maria Clara Urbano, Rafael José Vieira, Yi‐Kui Xiang, Sara Gil‐Mata, Anna Bedbrook, Baharudin Abdullah, Mona Al‐Ahmad, Maryam Ali Al‐Nesf, Emilio Alvarez‐Cuesta, Salma Mussagy Amade, Julijana Asllani, Kazi S. Bennoor, Elena Camelia Berghea, Mario Calvo‐Gil, Luis R. Caraballo, Elizabeth Castro, Lorenzo Cecchi, Deepa Choudhury, George Christoff, Derek K. Chu, Ieva Cirule, Alvaro A. Cruz, Dejan Dokic, Bilun Gemicioglu, Maria Antonieta Guzman, Ineta Grisle, Tari Haahtela, Elham Hossny, Wolfram Hoetzenecker, Martin Hrubisko, Tomohisa Iinuma, Zhanat Ispayeva, Juan Carlos Ivancevich, Fanny Wai San Ko, Helga Kraxner, Maciej Kupczyk, Violeta Kvedariene, Yen Lam, Désirée E. Larenas‐Linnemann, Bassam Mahboub, Padukudru A. Mahesh, Mohammed Reza Masjedi, Garry McDonald, Amarilis Melendez, Florin Mihaltan, Branislava Milenkovic, Yousser Mohammad, Marek Niedoszytko, Robyn E. O'Hehir, Carmen Panaitescu, Petr Panzner, Nikolaos G. Papadopoulos, José Miguel Fuentes Perez, Nhân Pham‐Thi, Constantinos Pitsios, Davor Plavec, María Susana Repka‐Ramirez, Jan Romantowski, Marylin Valentin Rostan, Menachem Rottem, Hani Salim, Pongsakorn Tantilipikorn, Vesna Tomic‐Spiric, Arunas Valiulis, Leticia de las Vecillas, Maria Teresa Ventura, Dana Wallace, Pascal Werminghaus, Sian Williams, Francisco Javier Plaza Zamora, Ludger Klimek, Torsten Zuberbier, Ana Margarida Pereira, João A. Fonseca, Jean Bousquet, Bernardo Sousa‐Pinto   +75 more
wiley   +1 more source

Analyzing of Production Conditions of 89Zr in the Particle Accelerator

Cumhuriyet Science Journal, 2019
Nowadays 89Zr is outstanding PET radionuclidewith its physical half-life (t1/2 ~ 78 hours), useful decay specifications andso that it is suitable for antibody-based immuno-PET.
Özge Kozguş Güldü, Perihan Ünak, Buğra Gökhun Bulduk, Volkan Tekin, Ayfer Yurt Kılçar   +4 more
doaj   +1 more source

Multimodal imaging of pancreatic beta cells in vivo by targeting transmembrane protein 27 (TMEM27) [PDF]

, 2018
Aims/hypothesis: Non-invasive diagnostic tools specific for pancreatic beta cells will have a profound impact on our understanding of the pathophysiology of metabolic diseases such as diabetes.
Danzer, C., Dikaiou, K., Esterhazy, D., Fischer, E., Honer, M., Keist, R., Krek, W., Matile, H., Migliorini, C., Ripoll, J., Rudin, M., Schibli, R., Stoffel, M., Stuker, F., Vats, D., Wang, H.   +15 more
core  

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Dissociating role of Bassoon in glutamatergic and dopaminergic neurons in alcohol‐related behaviour and affective state in mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Alcohol abuse and affective disorders are severe comorbid psychiatric diseases characterized by impaired brain synaptic transmission. The role of presynaptic scaffolding proteins coordinating presynaptic plasticity and neurotransmitter release, such as Bassoon (Bsn), in the pathogenesis of these disorders remains elusive.
Liubov S. Kalinichenko, Mona Krenbauer, Janosh Isert, Marlon Kamlah, Thorben Tanzer, Hannes Rödel, Tobias Müller, Anil Annamneedi, Enes Yağız Akdaş, Volker Eulenburg, Bernd Lenz, Eckart D. Gundelfinger, Johannes Kornhuber, Anna Fejtova, Christian P. Müller   +14 more
wiley   +1 more source

Notoginsenoside‐Fa mitigates vascular endothelial permeability via targeting SUGT1 to stabilize NLRP3 in a resting state

British Journal of Pharmacology, EarlyView.
Background and Purpose Notoginsenoside‐Fa (Noto‐Fa) is an emerging active compound derived from notoginseng with promise in treating cardiovascular diseases. The development of cardiovascular diseases is intricately linked to the damage of vascular endothelium and it is widely acknowledged that numerous chronic inflammation pathways, especially the ...
Xiao‐Ying Yu, Da‐Hao Mai, Xing‐Ming Zhong, Li‐Ting Huang, Lan‐Ting Fu, He‐Cai Wang, Ke Wang, Hai‐Yan Li, Qiu‐He Chen, Yang Chen   +9 more
wiley   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source

Transition Into Clinical Routine and Survival Outcomes of BCL2‐ and BTK Inhibitors: An Analysis of Patient Data From the GCLLSG Registry

European Journal of Haematology, EarlyView.
ABSTRACT Within a dataset of the German CLL Study Group (GCLLSG) registry, 274 patients were allocated to a cohort with venetoclax and 888 to a cohort with BTKi (79 acalabrutinib, 809 ibrutinib), each as first administered targeted substance class within the documented treatment sequence.
Nadine Kutsch, Rudy Ligtvoet, Sandra Robrecht, Hartmut Linde, Thomas Illmer, Steffen Dörfel, Jörg Lipke, Ali Aldaoud, Rudolf Schlag, Jolanta Dengler, Othman Al‐Sawaf, Petra Langerbeins, Paula Cramer, Michael Hallek, Barbara Eichhorst, Kirsten Fischer, Anna Fink   +16 more
wiley   +1 more source

Bone Marrow Pathology in Cold Agglutinin‐Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases

European Journal of Haematology, EarlyView.
ABSTRACT Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia (AIHA). CAD occurs in the context of a small clonal B‐cell lymphoproliferation restricted to blood and/or bone marrow (BM), without overt or extramedullary lymphoma. The WHO‐HAEM5 introduced a description of the CAD‐associated lymphoproliferative disorder (CAD‐LPD) in ...
Anne‐Marie L. Becking, Sophie J. Bernelot Moens, Marie José Kersten, Femke V. M. Mulder, Steven T. Pals, Lianne Koens, Josephine M. I. Vos   +6 more
wiley   +1 more source