Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells [PDF]
Immunotoxins as antiviral therapeutics are largely unexplored but have promising prospective due to their high selectivity potential and their unparalleled efficiency.
Jeppesen, Mads G. +5 more
core +5 more sources
Therapeutic options in peripheral T cell lymphoma
Peripheral T cell lymphoma (PTCL) is a rare and heterogeneous group of non-Hodgkin lymphomas with a very poor prognosis. The standard first-line treatments have resulted in unsatisfactory patient outcomes.
Yaping Zhang +3 more
doaj +1 more source
Citation: 'immunoconjugate' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13279 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Zixuan Ye,1,* Yue Zhang,1,* Yuanfen Liu,2,* Yanyan Liu,1 Jiasheng Tu,1 Yan Shen1 1Department of Pharmaceutics, State Key Laboratory of Nature Medicines, China Pharmaceutical University, Nanjing, People’s Republic of China; 2Jiangsu Health ...
Ye Z +5 more
doaj
Rapid Generation of In Vitro Multicellular Spheroids for the Study of Monoclonal Antibody Therapy
Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates and are difficult to study in vitro. Cells cultured as monolayers typically exhibit less resistance to therapy than those grown in vivo.
Yen T. Phung, Dario Barbone, V. Courtney Broaddus, Mitchell Ho
doaj
Technical Considerations of Phosphorous-32 Bremsstrahlung SPECT Imaging after Radioembolization of Hepatic Tumors: A Clinical Assessment with a Review of Imaging Parameters [PDF]
Background. Bremsstrahlung (BS) imaging during radioembolization (RE) confirms the deposition of radiotracer in hepatic/ extrahepatic tumors. The aimof this study is to demonstrate 32P images and to optimize the imaging parameters.
Akhlaghpoor, Shahram +3 more
core
Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using 149Tb-rituximab [PDF]
This study demonstrates high-efficiency sterilisation of single cancer cells in a SCID mouse model of leukaemia using rituximab, a monoclonal antibody that targets CD20, labelled with terbium-149, an alpha-emitting radionuclide.
Beyer, G.-J +8 more
core
Targeting Melanoma via the Innate Immune System [PDF]
Over-expression of the folate receptor (FR) has been shown on the vascular side of cancerous cells including those of the breast, ovaries, testes, and cervix. However, FR over-expression has not yet been explored fully in melanoma.
Skinner, Cassandra
core
Site-Specifically Labeled Immunoconjugates for Molecular Imaging—Part 1: Cysteine Residues and Glycans [PDF]
core +1 more source
Production and employment impacts of new technologies: analysis for biotechnology [PDF]
Biotechnology is often regarded as a key technology with high potential for far-reaching social, environmental and economic impacts. Among others, the development and diffusion of biotechnology may have considerable economic effects on production and ...
Wydra, Sven
core

