Results 101 to 110 of about 7,735 (207)

Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells [PDF]

open access: yes, 2017
Immunotoxins as antiviral therapeutics are largely unexplored but have promising prospective due to their high selectivity potential and their unparalleled efficiency.
Jeppesen, Mads G.   +5 more
core   +5 more sources

Therapeutic options in peripheral T cell lymphoma

open access: yesJournal of Hematology & Oncology, 2016
Peripheral T cell lymphoma (PTCL) is a rare and heterogeneous group of non-Hodgkin lymphomas with a very poor prognosis. The standard first-line treatments have resulted in unsatisfactory patient outcomes.
Yaping Zhang   +3 more
doaj   +1 more source

immunoconjugate

open access: yes
Citation: 'immunoconjugate' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13279 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

EGFR Targeted Cetuximab-Valine-Citrulline (vc)-Doxorubicin Immunoconjugates- Loaded Bovine Serum Albumin (BSA) Nanoparticles for Colorectal Tumor Therapy

open access: yesInternational Journal of Nanomedicine, 2021
Zixuan Ye,1,* Yue Zhang,1,* Yuanfen Liu,2,* Yanyan Liu,1 Jiasheng Tu,1 Yan Shen1 1Department of Pharmaceutics, State Key Laboratory of Nature Medicines, China Pharmaceutical University, Nanjing, People’s Republic of China; 2Jiangsu Health ...
Ye Z   +5 more
doaj  

Rapid Generation of In Vitro Multicellular Spheroids for the Study of Monoclonal Antibody Therapy

open access: yesJournal of Cancer, 2011
Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates and are difficult to study in vitro. Cells cultured as monolayers typically exhibit less resistance to therapy than those grown in vivo.
Yen T. Phung, Dario Barbone, V. Courtney Broaddus, Mitchell Ho
doaj  

Technical Considerations of Phosphorous-32 Bremsstrahlung SPECT Imaging after Radioembolization of Hepatic Tumors: A Clinical Assessment with a Review of Imaging Parameters [PDF]

open access: yes, 2014
Background. Bremsstrahlung (BS) imaging during radioembolization (RE) confirms the deposition of radiotracer in hepatic/ extrahepatic tumors. The aimof this study is to demonstrate 32P images and to optimize the imaging parameters.
Akhlaghpoor, Shahram   +3 more
core  

Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using 149Tb-rituximab [PDF]

open access: yes, 2018
This study demonstrates high-efficiency sterilisation of single cancer cells in a SCID mouse model of leukaemia using rituximab, a monoclonal antibody that targets CD20, labelled with terbium-149, an alpha-emitting radionuclide.
Beyer, G.-J   +8 more
core  

Targeting Melanoma via the Innate Immune System [PDF]

open access: yes, 2012
Over-expression of the folate receptor (FR) has been shown on the vascular side of cancerous cells including those of the breast, ovaries, testes, and cervix. However, FR over-expression has not yet been explored fully in melanoma.
Skinner, Cassandra
core  

Production and employment impacts of new technologies: analysis for biotechnology [PDF]

open access: yes
Biotechnology is often regarded as a key technology with high potential for far-reaching social, environmental and economic impacts. Among others, the development and diffusion of biotechnology may have considerable economic effects on production and ...
Wydra, Sven
core  

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