Results 141 to 150 of about 1,577 (196)

αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility in mouse models. [PDF]

Nat Commun
Wang T, Xu Y, Zhang Z, Wu Y, Chen L, Zheng X, Peng H, Zou Q, Sun R, Ma H, Sun H, Tian Z, Zheng X.   +12 more
europepmc   +1 more source

Novel PD-1-targeted, activity-optimized IL-15 mutein SOT201 acting in cis provides antitumor activity superior to PD1-IL2v. [PDF]

J Immunother Cancer
Matuskova H, Marasek P, Mazhara V, Simonova E, Kosinova L, Danek P, Danova K, Sajnerova K, Malatova I, Hrabankova K, Greco D, Martinec O, Fabisik M, Podzimkova N, Hladikova K, Behalova K, Antosova Z, Sirova M, Mikyskova R, Reinis M, Kovar M, Béchard D, Moebius U, Palova Jelinkova L, Spisek R, Steegmaier M, Adkins I.   +26 more
europepmc   +1 more source

Advanced cytokine-based immunotherapies: targeted cis-delivery strategies for enhanced anti-tumor efficacy and reduced toxicity. [PDF]

MAbs
Pousse L, Manchala A, Klein C, Codarri Deak L.   +3 more
europepmc   +1 more source

IGM-7354, an Immunocytokine with IL15 Fused to an Anti-PD-L1 IgM, Induces NK and CD8+ T cell-Mediated Cytotoxicity of PD-L1-Positive Tumor Cells. [PDF]

Cancer Immunol Res
Desbois M, Giffon T, Yakkundi P, Denson CR, Sekar K, Hart KC, Santos D, Calhoun SE, Logronio K, Pandey S, Ng D, Saini AK, Wang BT, Keyt BA, Sinclair AM, Kotturi MF.   +15 more
europepmc   +1 more source

Novel immunocytokines for cancer therapy

, 2012
openaire   +2 more sources

Treatment Strategies for Advanced Cutaneous Squamous Cell Carcinoma Following Anti-PD-1 Immunotherapy Failure: A Systematic Review of the Literature and Ongoing Trials. [PDF]

Cancers (Basel)
Thomson H, Adala E, Mandal A, Jones C, Sacco JJ.   +4 more
europepmc   +1 more source

Tumor-Homing Antibody-Cytokine Fusions for Cancer Therapy. [PDF]

Onco Targets Ther
Prodi E, Neri D, De Luca R.
europepmc   +1 more source

Local delivery of cell surface-targeted immunocytokines programs systemic antitumor immunity. [PDF]

Nat Immunol
Santollani L, Maiorino L, Zhang YJ, Palmeri JR, Stinson JA, Duhamel LR, Qureshi K, Suggs JR, Porth OT, Pinney W, Msari RA, Walsh AA, Wittrup KD, Irvine DJ.   +13 more
europepmc   +1 more source

Cytokine/Antibody Fusion Protein Design and Evaluation. [PDF]

Curr Protoc
Fabilane CS, Stephenson AC, Leonard EK, VanDyke D, Spangler JB.   +4 more
europepmc   +1 more source