Results 11 to 20 of about 468,207 (168)

Autoimmunity in Immunodeficiency [PDF]

Current Allergy and Asthma Reports, 2013
Primary immunodeficiencies (PID) comprise a diverse group of clinical disorders with varied genetic defects. Paradoxically, a substantial proportion of PID patients develop autoimmune phenomena in addition to having increased susceptibility to infections from their impaired immunity.
Krista, Todoric, Jessica B, Koontz, Daniel, Mattox, Teresa K, Tarrant   +3 more
openaire   +2 more sources

CD160 Promotes NK Cell Functions by Upregulating Glucose Metabolism and Negatively Correlates With HIV Disease Progression

Frontiers in Immunology, 2022
Natural killer (NK) cells are crucial for immune responses to viral infections. CD160 is an important NK cell activating receptor, with unknown function in HIV infection.
Zheng Sun, Zheng Sun, Zheng Sun, Yidi Li, Yidi Li, Yidi Li, Zining Zhang, Zining Zhang, Zining Zhang, Yajing Fu, Yajing Fu, Yajing Fu, Xiaoxu Han, Xiaoxu Han, Xiaoxu Han, Qinghai Hu, Qinghai Hu, Qinghai Hu, Haibo Ding, Haibo Ding, Haibo Ding, Hong Shang, Hong Shang, Hong Shang, Hong Shang, Yongjun Jiang, Yongjun Jiang, Yongjun Jiang   +27 more
doaj   +1 more source

Combined immunodeficiencies

Jornal de Pediatria, 2021
Inborn Errors of Immunity (IEI), also known as primary immunodeficiencies, correspond to a heterogeneous group of congenital diseases that primarily affect immune response components. The main clinical manifestations comprise increased susceptibility to infections, autoimmunity, inflammation, allergies and malignancies.
Carolina Sanchez Aranda, Rafaela Rola Guimarães, Mariana de Gouveia-Pereira Pimentel   +2 more
openaire   +5 more sources

Immunodeficiencies

Clinical and Experimental Immunology, 2009
SummaryPrimary immunodeficiencies (PIDs) are uncommon, chronic and severe disorders of the immune system in which patients cannot mount a sufficiently protective immune response, leading to an increased susceptibility to infections. The treatment of choice for PID patients with predominant antibody deficiency is intravenous immunoglobulin (Ig ...
Ballow, Mark, Notarangelo, Luigi, Grimbacher, Bodo, Cunningham-Rundles, Charlotte, Stein, Mark R., Helbert, Matthew, Gathmann, Benjamin, Kindle, G., Knight, A. K., Ochs, Hans D., Sullivan, Kathleen E., Franco, José Luis   +11 more
openaire   +5 more sources

Recurrent Vulvovaginal Candidiasis: Could It Be Related to Cell-Mediated Immunity Defect in Response to Candida Antigen? [PDF]

International Journal of Fertility and Sterility, 2017
Background Recurrent vulvovaginal candidiasis (RVVC) is a common cause of morbidity affecting millions of women worldwide. Patients with RVVC are thought to have an underlying immunologic defect.
Zahra Talaei, Saba Sheikhbahaei, Vajihe Ostadi, Mazdak Ganjalikhani Hakemi, Mohsen Meidani, Elham Naghshineh, Majid Yaran, Alireza Emami Naeini, Roya Sherkat   +8 more
doaj   +1 more source

Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes

Biomedical Journal, 2021
Autoimmune lymphoproliferative syndrome (ALPS) is an inherited non-malignant and non-infectious lymphoproliferative syndrome caused by mutations in genes affecting the extrinsic apoptotic pathway (FAS, FASL, CASP10).
Laura Gámez-Díaz, Bodo Grimbacher
doaj   +1 more source

Sexually transmitted infections and viral hepatitides in patients presenting for non-occupational HIV post-exposure prophylaxis: results of a prospective cohort study

International Journal of Infectious Diseases, 2015
Data evaluating the screening practices for viral hepatitides and sexually transmitted infections (STIs) in patients presenting for non-occupational HIV post-exposure prophylaxis (nPEP) care are limited.
Nirojini Sivachandran, Reed A.C. Siemieniuk, Pauline Murphy, Andrea Sharp, Christine Walach, Tania Placido, Isaac I. Bogoch   +6 more
doaj   +1 more source

Mutation of Mycobacterium tuberculosis and Implications for Using Whole-Genome Sequencing for Investigating Recent Tuberculosis Transmission

Frontiers in Public Health, 2022
Tuberculosis (TB) control programs use whole-genome sequencing (WGS) of Mycobacterium tuberculosis (Mtb) for detecting and investigating TB case clusters. Existence of few genomic differences between Mtb isolates might indicate TB cases are the result of
Kristin N. Nelson, Sarah Talarico, Shameer Poonja, Clinton J. McDaniel, Martin Cilnis, Alicia H. Chang, Kala Raz, Wendy S. Noboa, Lauren Cowan, Tambi Shaw, James Posey, Benjamin J. Silk   +11 more
doaj   +1 more source

Primary immunodeficiency [PDF]

Allergy, Asthma & Clinical Immunology, 2018
Primary immunodeficiency disorder (PID) refers to a large heterogeneous group of disorders that result from defects in immune system development and/or function. PIDs are broadly classified as disorders of adaptive immunity (i.e., T cell, B-cell or combined immunodeficiencies) or of innate immunity (e.g., phagocyte and complement disorders).
McCusker, Christine, Upton, Julia, Warrington, Richard   +2 more
openaire   +4 more sources

Scoring Thoracic CT Scans of Patients with NFKB1-Related Disease for Clinical Management and Treatment Studies Using Four Parameters (Adapted from the Hartmann Score)

Journal of Human Immunity
BackgroundNFKB1 encodes the p105/p50 nuclear factor-kappa-B (NF-κB1) transcription factor. Heterozygous mutations in NFKB1 are associated with NFKB1-related disease, including granulomatous-lymphocytic interstitial lung disease (GLILD) or similar lung ...
Katharina Thoma, Manfred Fliegauf, Bärbel Keller, Maximilian Frederik Russe, Gabriele Müller, Michele Proietti, Andres Caballero Garcia de Oteyza, Pavla Mrovecova, Helene Kraus, Klaus Warnatz, Nadezhda Camacho Ordonez, Aleksandra Hirsch, Christoph Geier, Máté Krausz, Sigune Goldacker, Natalie Frede, Stephan Ehl, Sarah Salou, Shahrzad Bakhtiar, Maria Fasshauer, Michael Borte, Oliver Hausmann, Faranaz Atschekzei, Georgios Sogkas, Ansgar Schulz, Bodo Grimbacher, Prerana Agarwal   +26 more
doaj   +1 more source