Results 21 to 30 of about 619,127 (304)

Immunodeficiencies

Clinical and Experimental Immunology, 2009
SummaryPrimary immunodeficiencies (PIDs) are uncommon, chronic and severe disorders of the immune system in which patients cannot mount a sufficiently protective immune response, leading to an increased susceptibility to infections. The treatment of choice for PID patients with predominant antibody deficiency is intravenous immunoglobulin (Ig ...
Ballow, Mark, Notarangelo, Luigi, Grimbacher, Bodo, Cunningham-Rundles, Charlotte, Stein, Mark R., Helbert, Matthew, Gathmann, Benjamin, Kindle, G., Knight, A. K., Ochs, Hans D., Sullivan, Kathleen E., Franco, José Luis   +11 more
openaire   +5 more sources

Screening of functional and positional candidate genes in families with common variable immunodeficiency [PDF]

, 2008
Background: Common variable immunodeficiency (CVID) comprises a heterogeneous group of primary antibody deficiencies with complex clinical and immunological phenotypes.
Grimbacher, B, Thiel, J, Jung, J, Webster, A. David B., Webster, D, Schäffer, Alejandro A., Pan Hammarström, Q, Lougaris, V, Hammarström, L, Salzer, U, Hagena, Tina, Grimbacher, B., Jung, Johannes, Woellner, Cristina, MOSCHESE, VIVIANA, Schaffer, AA, Webster, DA, Birmelin, J, Pan-Hammarström, Qiang, Du, Likun, Schäffer, A, Birmelin, Jennifer, Woellner, C, Neumann, C, Salzer, Ulrich, Metin, A, Lougaris, Vassilios, Plebani, Alessandro, Hagena, T, Grimbacher, Bodo, Pan-Hammarstrom, Q, Du, L, Thiel, Jens, Hammarström, Lennart, Moschese, V, Hammarstroo, L, Metin, Ayse, Plebani, A, Neumann, Carla   +38 more
core   +1 more source

HUMAN IMMUNODEFICIENCY VIRUS AND CANCER IN CHILDREN IN SOUTH AFRICA [PDF]

, 2012
Background. Infection with human immunodeficiency virus-1 (HIV) increases the incidence of certain cancers in adults. Much less is known about the impact of infection on the risk of cancer in children. Aim.
Stefan, Daniela Cristina
core   +5 more sources

Differential utilization of CD134 as a functional receptor by diverse strains of feline immunodeficiency virus [PDF]

, 2006
The feline homologue of CD134 (fCD134) is the primary binding receptor for feline immunodeficiency virus (FIV), targeting the virus preferentially to activated CD4+ helper T cells.
McMonagle, E.L., Hosie, M.J., Willett, B.J., Ridha, S.   +3 more
core   +1 more source

Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes

Biomedical Journal, 2021
Autoimmune lymphoproliferative syndrome (ALPS) is an inherited non-malignant and non-infectious lymphoproliferative syndrome caused by mutations in genes affecting the extrinsic apoptotic pathway (FAS, FASL, CASP10).
Laura Gámez-Díaz, Bodo Grimbacher
doaj   +1 more source

Evolution of replication efficiency following infection with a molecularly cloned feline immunodeficiency virus of low virulence [PDF]

, 2002
The development of an effective vaccine against human immunodeficiency virus is considered to be the most practicable means of controlling the advancing global AIDS epidemic.
Hosie, M.J., Dunsford, T.H., Shimojima, M., Klein, D., Willett, B.J., Neil, J.C., Jarrett, O., Cannon, C.   +7 more
core   +1 more source

Sexually transmitted infections and viral hepatitides in patients presenting for non-occupational HIV post-exposure prophylaxis: results of a prospective cohort study

International Journal of Infectious Diseases, 2015
Data evaluating the screening practices for viral hepatitides and sexually transmitted infections (STIs) in patients presenting for non-occupational HIV post-exposure prophylaxis (nPEP) care are limited.
Nirojini Sivachandran, Reed A.C. Siemieniuk, Pauline Murphy, Andrea Sharp, Christine Walach, Tania Placido, Isaac I. Bogoch   +6 more
doaj   +1 more source

Mutation of Mycobacterium tuberculosis and Implications for Using Whole-Genome Sequencing for Investigating Recent Tuberculosis Transmission

Frontiers in Public Health, 2022
Tuberculosis (TB) control programs use whole-genome sequencing (WGS) of Mycobacterium tuberculosis (Mtb) for detecting and investigating TB case clusters. Existence of few genomic differences between Mtb isolates might indicate TB cases are the result of
Kristin N. Nelson, Sarah Talarico, Shameer Poonja, Clinton J. McDaniel, Martin Cilnis, Alicia H. Chang, Kala Raz, Wendy S. Noboa, Lauren Cowan, Tambi Shaw, James Posey, Benjamin J. Silk   +11 more
doaj   +1 more source

Upregulation of surface feline CXCR4 expression following ectopic expression of CCR5: implications for studies of the cell tropism of feline immunodeficiency virus [PDF]

, 2002
Feline CXCR4 and CCR5 were expressed in feline cells as fusion proteins with enhanced green fluorescent protein (EGFP). Expression of the EGFP fusion proteins was localized to the cell membrane, and surface expression of CXCR4 was confirmed by using a ...
Hosie, M.J., Willett, B.J., Cannon, C.A.
core   +1 more source

Scoring Thoracic CT Scans of Patients with NFKB1-Related Disease for Clinical Management and Treatment Studies Using Four Parameters (Adapted from the Hartmann Score)

Journal of Human Immunity
BackgroundNFKB1 encodes the p105/p50 nuclear factor-kappa-B (NF-κB1) transcription factor. Heterozygous mutations in NFKB1 are associated with NFKB1-related disease, including granulomatous-lymphocytic interstitial lung disease (GLILD) or similar lung ...
Katharina Thoma, Manfred Fliegauf, Bärbel Keller, Maximilian Frederik Russe, Gabriele Müller, Michele Proietti, Andres Caballero Garcia de Oteyza, Pavla Mrovecova, Helene Kraus, Klaus Warnatz, Nadezhda Camacho Ordonez, Aleksandra Hirsch, Christoph Geier, Máté Krausz, Sigune Goldacker, Natalie Frede, Stephan Ehl, Sarah Salou, Shahrzad Bakhtiar, Maria Fasshauer, Michael Borte, Oliver Hausmann, Faranaz Atschekzei, Georgios Sogkas, Ansgar Schulz, Bodo Grimbacher, Prerana Agarwal   +26 more
doaj   +1 more source