Results 31 to 40 of about 607,896 (303)

Immunodeficiencies

Clinical and Experimental Immunology, 2009
SummaryPrimary immunodeficiencies (PIDs) are uncommon, chronic and severe disorders of the immune system in which patients cannot mount a sufficiently protective immune response, leading to an increased susceptibility to infections. The treatment of choice for PID patients with predominant antibody deficiency is intravenous immunoglobulin (Ig ...
Ballow, Mark, Notarangelo, Luigi, Grimbacher, Bodo, Cunningham-Rundles, Charlotte, Stein, Mark R., Helbert, Matthew, Gathmann, Benjamin, Kindle, G., Knight, A. K., Ochs, Hans D., Sullivan, Kathleen E., Franco, José Luis   +11 more
openaire   +5 more sources

Mapping the domains of CD134 as a functional receptor for feline immunodeficiency virus (FIV) [PDF]

, 2006
The feline homologue of CD134 (fCD134) is the primary binding receptor for feline immunodeficiency virus (FIV), targeting the virus preferentially to activated CD4+ helper T cells.
Bonci, F., Hosie, MJ, Bonci F, Willett BJ, Hosie MJ, Bonci, F, McMonagle, E.L., Hosie, M.J., Pistello, M, McMonagle EL, McMonagle, EL, Willett, B.J., Willett, BJ, PISTELLO, MAURO, Pistello, M.   +14 more
core   +1 more source

Screening of functional and positional candidate genes in families with common variable immunodeficiency [PDF]

, 2008
Background: Common variable immunodeficiency (CVID) comprises a heterogeneous group of primary antibody deficiencies with complex clinical and immunological phenotypes.
Grimbacher, B, Thiel, J, Jung, J, Webster, A. David B., Webster, D, Schäffer, Alejandro A., Pan Hammarström, Q, Lougaris, V, Hammarström, L, Salzer, U, Hagena, Tina, Grimbacher, B., Jung, Johannes, Woellner, Cristina, MOSCHESE, VIVIANA, Schaffer, AA, Webster, DA, Birmelin, J, Pan-Hammarström, Qiang, Du, Likun, Schäffer, A, Birmelin, Jennifer, Woellner, C, Neumann, C, Salzer, Ulrich, Metin, A, Lougaris, Vassilios, Plebani, Alessandro, Hagena, T, Grimbacher, Bodo, Pan-Hammarstrom, Q, Du, L, Thiel, Jens, Hammarström, Lennart, Moschese, V, Hammarstroo, L, Metin, Ayse, Plebani, A, Neumann, Carla   +38 more
core   +1 more source

Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes

Biomedical Journal, 2021
Autoimmune lymphoproliferative syndrome (ALPS) is an inherited non-malignant and non-infectious lymphoproliferative syndrome caused by mutations in genes affecting the extrinsic apoptotic pathway (FAS, FASL, CASP10).
Laura Gámez-Díaz, Bodo Grimbacher
doaj   +1 more source

Differential utilization of CD134 as a functional receptor by diverse strains of feline immunodeficiency virus [PDF]

, 2006
The feline homologue of CD134 (fCD134) is the primary binding receptor for feline immunodeficiency virus (FIV), targeting the virus preferentially to activated CD4+ helper T cells.
McMonagle, E.L., Hosie, M.J., Willett, B.J., Ridha, S.   +3 more
core   +1 more source

Selective expansion of viral variants following experimental transmission of a reconstituted feline immunodeficiency virus quasispecies [PDF]

, 2013
Following long-term infection with virus derived from the pathogenic GL8 molecular clone of feline immunodeficiency virus (FIV), a range of viral variants emerged with distinct modes of interaction with the viral receptors CD134 and CXCR4, and ...
Margaret J Hosie, Martin Kraase (276419), McMonagle Elizabeth, Kraase, M., Varela, M., Mariana Varela (81646), Kraase Martin, Nicola Logan (276420), Mariana Varela, Hosie Margaret J., Brian J Willett, Brian J. Willett (276418), Logan Nicola, Elizabeth McMonagle (276421), Willett Brian J., Hosie, M.J., Varela Mariana, Nicola Logan, Logan, N., Willett, B.J., McMonagle, E., Margaret J. Hosie (276422), Elizabeth McMonagle, Martin Kraase   +23 more
core   +1 more source

A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction [PDF]

, 2008
Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry.
Margaret J Hosie, Ayman Samman, Willett Brian J, Samman, Ayman, Logan Nicola, Brian J Willett, Samman Ayman, McMonagle, Elizabeth L., Hosie Margaret J, Logan, Nicola, McMonagle Elizabeth L, Nicola Logan, Hosie, Margaret J., Willett, Brian J., Elizabeth L McMonagle   +14 more
core   +1 more source

Sexually transmitted infections and viral hepatitides in patients presenting for non-occupational HIV post-exposure prophylaxis: results of a prospective cohort study

International Journal of Infectious Diseases, 2015
Data evaluating the screening practices for viral hepatitides and sexually transmitted infections (STIs) in patients presenting for non-occupational HIV post-exposure prophylaxis (nPEP) care are limited.
Nirojini Sivachandran, Reed A.C. Siemieniuk, Pauline Murphy, Andrea Sharp, Christine Walach, Tania Placido, Isaac I. Bogoch   +6 more
doaj   +1 more source

Neopterin and [beta]2-microglobulin as prognostic indices in human immunodeficiency virus type 1 infection [PDF]

, 1991
Fuchs D, Krämer A, Reibnegger G, et al. Neopterin and [beta]2-microglobulin as prognostic indices in human immunodeficiency virus type 1 infection. Infection.
Werner, Ernst R., Fuchs, Dietmar, Krämer, Alexander ; https://orcid.org/, Goedert, James J., Reibnegger, Gilbert, Dierich, M. P., Wachter, Helmut   +6 more
core   +1 more source

Disease progression in Human Immunodeficiency Virus type 1 infected viraemic controllers [PDF]

, 2012
PhDBackground: The mechanism of CD4+ T-cell decline in Human Immunodeficiency Virus-1 (HIV-1) infection is unclear, but the association with plasma HIV-1 RNA-load suggests viral replication is involved.
Groves, Katherine Claire
core   +4 more sources