Results 51 to 60 of about 3,500 (164)

The Effect of Lipemia on Insulin and Adiponectin Measurement in Equine Blood Samples

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Background Lipemia is a common comorbidity in horses with obesity or equine metabolic syndrome, but the impact of lipemia on the measurement of insulin and adiponectin has not been evaluated. Objective To evaluate endogenous and exogenous lipemic interference with equine insulin and adiponectin measurements via several commercial assays ...
Kimberly L. Hallowell   +3 more
wiley   +1 more source

Lymphocyte subsets in human immunodeficiency virus-unexposed Brazilian individuals from birth to adulthood

open access: yesMemorias do Instituto Oswaldo Cruz, 2014
Ethnic origin, genetics, gender and environmental factors have been shown to influence some immunologic indices, so that development of reference values for populations of different backgrounds may be necessary.
Maria Isabel de Moraes-Pinto   +7 more
doaj   +1 more source

Neisseria gonorrhoeae Multivalent Maxibody with a Broad Spectrum of Strain Specificity and Sensitivity for Gonorrhea Diagnosis

open access: yesBiomolecules, 2021
Gonorrhea is one of the most common, but still hidden and insidious, sexually transmitted diseases caused by Neisseria gonorrhoeae (gonococci). However, the diagnosis and treatment of gonorrhea are hampered by antigenic variability among gonococci, the ...
Jieun Jeong   +5 more
doaj   +1 more source

Evaluation of an Immunoturbidometric Assay for Measurement of Total Adiponectin Concentration in Equine Serum Samples

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Background Total adiponectin (TA) is a marker of metabolic health in equids, with values below a critical decision point of < 7.9 μg/mL conferring increased risk of laminitis. Objectives To evaluate an IT assay to measure serum [TA] in equids and to assess its correlation with [high molecular weight adiponectin] (HMWA) measured by ELISA ...
Rose D. Nolen‐Walston   +5 more
wiley   +1 more source

Clinically relevant intra‐articular corticosteroid doses impair equine osteoclast function in vitro

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To assess the effects of clinically relevant doses of commonly employed intra‐articular corticosteroids—specifically, triamcinolone acetonide (TCA), methylprednisolone acetate (MPA), and combination of betamethasone acetate and betamethasone sodium phosphate (BM)—on equine osteoclasts.
Gwladys Malek   +4 more
wiley   +1 more source

Effects of 14 days of head‐down bed rest with or without exercise, and subsequent recovery on bone turnover, density and structure in older adults

open access: yesExperimental Physiology, EarlyView.
Abstract Bed rest accelerates bone loss and may exacerbate skeletal fragility. This study examined the effects of 14 days of head‐down tilt bed rest (HDBR) with or without exercise, and subsequent recovery, on bone turnover, density and structure in older adults. Twenty‐two healthy older adults (55–65 years) completed the HDBR protocol.
Guy Hajj‐Boutros   +11 more
wiley   +1 more source

Using CAST-test to investigate human specific hypersensitivity to the anthrax pathogen

open access: yesМедицинская иммунология, 2020
We present the results of applying functional cytometric test of antigen-stimulated activation basophils to assess specific immunological reactivity in the people with anthrax, and immunized with anthrax vaccine.
D. G. Ponomarenko   +9 more
doaj   +1 more source

Effects of Trazodone on Testicular Morphology, Sperm Parameters and Contractility of the Distal Cauda Epididymal Duct in Rats

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Trazodone is an antidepressant approved for the treatment of major depressive disorder and is associated with a low incidence of sexual dysfunction. However, its effects on male reproductive health are not yet fully understood. Therefore, this study aimed to evaluate the effects of repeated trazodone administration on reproductive parameters ...
Maria Santana da Silva   +13 more
wiley   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

open access: yesAdvanced Materials, Volume 38, Issue 49, 1 September 2026.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot   +3 more
wiley   +1 more source

Possibilities of post-mortem diagnostics, including immunodiagnostics, in cases of sudden death due to anaphylactic and anaphylactoid reactions

open access: yes, 2014
Postmortem diagnostics of anaphylactic and anaphylactoid reaction as the cause of death in cases of sudden deaths without witnesses, as well as those in which circumstances of sudden disease and then death are known, seems to be very difficult.
Mariusz Kobek   +5 more
core   +1 more source

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