Results 71 to 80 of about 3,500 (164)

In vitro models for the study of Zika virus

Журнал микробиологии, эпидемиологии и иммунобиологии, 2020
Due to the globalization, increased trade and migration flows the probability of outbreaks of Zika fever is significantly increasing worldwide, including Black sea coast of the Caucasus in the Russian Federation. Zika fever tends to spread rapidly and to
Ekaterina V. Pimenova, Natalya P. Khrapova, Tatyana V. Zamarina   +2 more
doaj   +1 more source

Targeting RANKL Prevents Bone Loss, Improves Muscle Function and Extends Lifespan in Progeroid Mice

Aging Cell, Volume 25, Issue 8, August 2026.
Targeting of RANKL by genetic and pharmacological approaches ameliorates key features of the progeroid phenotype in Zmpste24−/− mice. RANKL intervention restores bone mass, improves muscle phenotype, and extends survival. These findings support further exploration of RANKL‐targeted therapies for Hutchinson‐Gilford progeria syndrome.
Sandra Freitas‐Rodríguez, Alejandra Valle‐Cao, Francisco Rodríguez, Manuel Fernández‐Sanjurjo, Benjamín Fernández‐García, Vanessa Loredo, María Teresa Fernández‐García, Carmen Fiuza‐Luces, Alejandro Lucia, Carlos López‐Otín, Alejandro López‐Soto, Alicia R. Folgueras   +11 more
wiley   +1 more source

The Role of p38 MAPK in the Aetiopathogenesis of Psoriasis and Psoriatic Arthritis

Clinical and Developmental Immunology, 2013
The pathogenetic mechanisms responsible for the induction of immune-mediated disorders, such as psoriasis, remain not well characterized. Molecular signaling pathways are not well described in psoriasis, as well as psoriatic arthritis, which is seen in ...
Athanasios Mavropoulos, Eirini I. Rigopoulou, Christos Liaskos, Dimitrios P. Bogdanos, Lazaros I. Sakkas   +4 more
doaj   +1 more source

Disruption of Claudin‐2 and Trpv6 Results in Hypocalcemia, Hypercalciuria, and Altered Bone Microarchitecture in Mice

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Transepithelial calcium absorption occurs via a transcellular or paracellular pathway. The intestinal transcellular pathway relies, at least partially, on the apical calcium channel transient receptor potential vanilloid 6 (TRPV6), whereas paracellular calcium (re)absorption occurs through tight junction proteins, including claudin‐2 (CLDN2 ...
Harneet Kaur Bhullar, Amanda Lima Deluque, Debbie D. O'Neil, Wanling Pan, Michael R. Doschak, Henrik Dimke, R. Todd Alexander   +6 more
wiley   +1 more source

Current Progress and Future Directions for Tau-Based Fluid Biomarker Diagnostics in Alzheimer’s Disease [PDF]

, 2020
Funding: Research activity relating to tau-based immunodiagnostics performed by the Scottish Biologics Facility was funded by Genting TauRx Diagnostic Centre Sdn. Bhd.
Palliyil, Soumya, Lewis K. Penny, Harrington, Charles R, Richard Lofthouse, Arastoo, Mohammad, Charles R. Harrington, Andy Porter, Mohammad Arastoo, Wischik, Claude M, Claude M. Wischik, Porter, Andy, Lofthouse, Richard, Penny, Lewis, Soumya Palliyil   +13 more
core   +1 more source

CUZD1 and Anti-CUZD1 Antibodies as Markers of Cancer and Inflammatory Bowel Diseases

Clinical and Developmental Immunology, 2013
CUZD1, the CUB, and zona pellucida-like domains-containing protein 1, is a newly identified antigen of pancreatic autoantibodies (PAB) giving a reticulogranular pattern in patients with inflammatory bowel diseases, and in particular Crohn’s disease.
Christos Liaskos, Eirini I. Rigopoulou, Timoklia Orfanidou, Dimitrios P. Bogdanos, Christos N. Papandreou   +4 more
doaj   +1 more source

THROMBOCYTOPENIA IN THE STRUCTURE OF HEMATOLOGICAL DISORDERS IN PATIENTS OF A MULTIPROFILE HOSPITAL AND POSSIBLE WAYS TO OPTIMIZE ITS EVALUATION

Медицинский совет, 2018
Analysis of the prevalence of thrombocytopenia in a multidisciplinary hospital, where it is treated about 25,000 patients a year, shows that from 1.15% to 1.45% of patients have threat reduction platelets less than 100x109/l.
S. Yu. Semigolovskii, T. V. Vavilova, V. A. Kashchenko, S. N. Semigolovskii, A. A. Sapegin   +4 more
doaj   +1 more source

Printable Paper-Based Immunodiagnostics

, 2010
We modified the structural properties of paper and applied inkjet printing to biofunctionalize paper in order to fabricate inexpensive, sustainable and disposable bioassays.
Teerinen, Tuija, Olkkonen, Juuso, Lappalainen, Timo, Hakalahti, Leena, Erho, Tomi, Vento, Pia   +5 more
core   +2 more sources

Identification of nonlinear lateral flow immunoassay state-space models via particle filter approach [PDF]

, 2012
This is the post-print of the Article. The official published version can be accessed from the link below - Copyright @ 2012 IEEEIn this paper, the particle filtering approach is used, together with the kernel smoothing method, to identify the state ...
Zidong Wang, Min Du, Zeng, N, Liu, X, Wang, Z, Nianyin Zeng, Xiaohui Liu, Li, Y, Yurong Li, Du, M   +9 more
core   +1 more source

Development and validation of a regionally adapted sandwich enzyme-linked immunosorbent assay targeting recombinant p60 antigen for rapid detection of Listeria monocytogenes in food samples [PDF]

Veterinary World
Background and Aim: Listeria monocytogenes remains a major foodborne pathogen globally, with mortality rates ranging from 20%–40%. The increasing incidence of listeriosis and the limitations of culture-based and polymerase chain reaction-based ...
Guldarigash Kaukabayeva , Aigerim Turgimbayeva, Zhanar Akhmetkarimova, Sholpan Mukhlis, Gulkhan Unysheva, Sailau Abeldenov, Pavel Shevchenko, Albina Gabitova, Raushan Rychshanova, Aralbek Rsaliyev, Yergali Abduraimov, Saule Eskendirova   +11 more
doaj   +1 more source