Non-HLA Autoantibodies Associate With a Positive Flow-Crossmatch Pre- and Chronic Lung Allograft Dysfunction Post- Lung Transplant. [PDF]
HLAABSTRACT Antibodies to HLA are a major cause of chronic lung allograft dysfunction (CLAD) following lung transplantation (LTx), however mounting evidence indicates non‐HLA autoantibodies may also play a role. LTx recipients may have increased autoantibodies related to their native disease, and these may impact both pre‐transplant assays and LTx ...
Hiho S +7 more
europepmc +2 more sources
The Role of Immunogenetics in the Host–Parasite Interaction of Chagas Disease: Implications for Personalized Medicine [PDF]
Tropical Medicine and Infectious DiseaseChagas disease, caused by the protozoan parasite Trypanosoma cruzi, continues to be a significant global health issue, especially in Latin America, with increasing international prevalence due to migration. Despite advancements in diagnosis and treatment,
Muhammad Hassnain +5 more
doaj +2 more sources
Immun Inflamm DisImmunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
europepmc +3 more sources
Rhesus blood group haplotype determination by nanopore sequencing and adaptive sampling enables the precise determination of complex allele combinations that could not be accurately determined by standard methods. [PDF]
TransfusionAbstract Background Patients with chronic transfusion needs such as those with sickle cell disease face a high risk of developing antibodies against high‐prevalence antigens in the RH blood group system, complicating transfusion therapy and potentially necessitating stem cell transplantation.
Waldmann R +9 more
europepmc +2 more sources
HLA incompatibility mitigation strategies in off-the-shelf cancer immunotherapies: clinical implications and a practical framework for strategy selection and combination [PDF]
Frontiers in ImmunologyRajdeep Das +5 more
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New Perspectives on Immune Involvement in Parkinson’s Disease Pathogenesis
Journal of Parkinson’s Disease, 2022 Accumulating evidence implicates immune dysfunction in the etiology of Parkinson’s disease (PD). For instance, impaired cellular and humoral immune responses are emerging as established pathological hallmarks in PD. Further, in experimental models of PD,
David Gate
doaj +1 more source
Frontiers in Immunology, 2020 IMGT®, the international ImMunoGeneTics information system® is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT® marked the advent of immunoinformatics,
Perrine Pégorier +10 more
doaj +1 more source
Biomolecules, 2022 IMGT®, the international ImMunoGeneTics information system®, created in 1989, by Marie-Paule Lefranc (Université de Montpellier and CNRS), marked the advent of immunoinformatics, a new science which emerged at the interface between immunogenetics and ...
Marie-Paule Lefranc, Gérard Lefranc
doaj +1 more source
Current HLA Investigations on SARS-CoV-2 and Perspectives
Frontiers in Genetics, 2021 The rapid, global spread of the SARS-CoV-2 virus during the current pandemic has triggered numerous efforts in clinical and research settings to better understand the host genetics’ interactions and the severity of COVID-19.
Venceslas Douillard +8 more
doaj +1 more source