Results 91 to 100 of about 21,232 (243)

IMGT/mAb-KG: the knowledge graph for therapeutic monoclonal antibodies

Frontiers in Immunology
IntroductionTherapeutic monoclonal antibodies (mAbs) have demonstrated promising outcomes in diverse clinical indications, including but not limited to graft rejection, cancer, and autoimmune diseases lately.Recognizing the crucial need for the ...
Gaoussou Sanou, Gaoussou Sanou, Taciana Manso, Konstantin Todorov, Véronique Giudicelli, Patrice Duroux, Sofia Kossida   +6 more
doaj   +1 more source

MHC (RT1) and CD45 (RT7) immunogenetics of strain combinations used for the bone marrow transplantation model.

, 2016
MHC (RT1) and CD45 (RT7) immunogenetics of strain combinations used for the bone marrow transplantation model.
Hüseyin Bektas (562057), Florian W. R. Vondran (476274), Wolf Ramackers (562053), Mark D. Jäger (562055), Hans J. Schlitt (165204), Tilmann Röseler (2637457), Kai Timrott (716924), Jürgen Klempnauer (562056)   +7 more
core   +1 more source

Iptacopan monotherapy resulted in increased hemoglobin level in patients with PNH and hemoglobin ≥10 g/dL after anti‐C5 therapy

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Patients with paroxysmal nocturnal hemoglobinuria (PNH) on anti‐C5 often experience extravascular hemolysis with anemia. Iptacopan, the first oral proximal complement inhibitor targeting factor B, has shown efficacy and safety in PNH patients. APPULSE‐PNH (NCT05630001), a phase 3b, single‑arm, open‐label trial, enrolled adult patients with PNH
Austin Kulasekararaj, Flore S. de Fontbrune, Anna Gaya, Ilene Weitz, David J. Kuter, Bhumika J. Patel, David J. Araten, Abhay Singh, Jun H. Jang, Richard J. Kelly, Eros Di Bona, Michael Loschi, Vinod Pullarkat, Jörg Schubert, Rosario Notaro, Mustafa N. Yenerel, Joan Beckman, Nicolas Blin, Irina Murakhovskaya, Jens Panse, Eloy Roman, Alexander Röth, Hubert Schrezenmeier, Srinivas Tantravahi, Régis P. de Latour, Navin Mahajan, Luca Monaco, Tao Ding, Tomasz Lawniczek, Philippe Ferber, Marion Dahlke, Antonio M. Risitano   +31 more
wiley   +1 more source

Access to diagnosis using liquid biopsy (ADLiB): Identifying lymphoma in a tuberculosis‐endemic setting

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract In HIV‐ and tuberculosis (TB)‐endemic regions, lymphoma diagnosis is often delayed because symptoms can overlap with TB, and access to biopsy and specialized pathology is limited. To address this, we developed and internally evaluated the Access to Diagnosis using Liquid Biopsy (ADLiB) platform—a plasma cell‐free DNA (cfDNA)‐based approach ...
Katherine Antel, Nina Xiong, Mwanasha Merrill, Taiyang Chen, Lauren McGrath, Clara Droessler, Maxine van der Schyff, Meng‐Xuan Wu, Dylan Cheddie, Charlotte Slome, Liam McBride, Jonathan Day, Zainab Mohamed, Nazia Fakie, Nomonde Mbatani, Charlotte Shultz, Graeme Meintjes, Svitlana Tyekucheva, Elizabeth F. Cohen, Michael Y. Tolstorukov, Estelle Verburgh, Mark A. Murakami   +21 more
wiley   +1 more source

IMMUNOGENETICS OF RABBIT LOW-DENSITY LIPOPROTEINS.

, 1969
IMMUNOGENETICS OF RABBIT LOW-DENSITY ...
JOHN JOSEPH. ALBERS (7974092)
core  

IMGT-Choreography for immunogenetics and immunoinformatics.

, 2005
International audienceIMGT, the international ImMunoGeneTics information system (http://imgt.cines.fr), was created in 1989 at Montpellier, France. IMGT is a high quality integrated knowledge resource specialized in immunoglobulins (IG), T cell receptors
Combres, Kora, Chaume, Denys, Kaas, Quentin, Duprat, Elodie, Lefranc, Gérard, Ginestoux, Chantal, Chastellan, Patrick, Giudicelli, Véronique, Lefranc, Marie-Paule, Clément, Olivier, Coelho, Isabelle   +10 more
core   +1 more source

FAIRness and Immunogenetics

, 2020
For many decades, the immunogenetics community has been among the frontrunners in sharing data and samples, ensuring a great scientific progress in this domain. International histocompatibility workshops and scientific meetings in immunogenetics societies as EFI and ASHI have largely contributed to this progress.
Thomsen, Mogens, Mabile, Laurence, David, Romain, Cambon-Thomsen, Anne   +3 more
openaire   +2 more sources

IMGT, the international ImMunoGeneTics database

, 1999
IMGT, the international ImMunoGeneTics database (http://imgt.cnusc.fr:8104), is a high-quality integrated database specialising in Immunoglobulins (Ig), T cell Receptors (TcR) and Major Histocompatibility Complex (MHC) molecules of all vertebrate species,
Chaume, Denys, Müller, Werner, Bontrop, Ronald, Bodmer, Julia, Ginestoux, Chantal, Müller, Werner; id_orcid, Lemaitre, Marc, Giudicelli, Véronique, Barbié, Valérie, Lefranc, Marie Paule, Lefranc, Marie-Paule, Malik, Ansar   +11 more
core   +1 more source

Cold Agglutinin Disease–Like Genetic Signatures in Lymphoplasmacytic Lymphoma–Like Cases Challenge the WHO Fifth Edition Classification

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background The fifth edition of the World Health Organization (WHO) classification defines cold agglutinin disease (CAD) as a clonal B‐cell lymphoproliferative disorder occurring in the absence of overt lymphoma, whereas cases associated with lymphoma are classified as cold agglutinin syndrome (CAS).
Yuki Sato, Daisuke Koyama, Shoki Yamada, Kengo Suzuki, Masahiko Fukatsu, Yuka Oka, Yuko Hashimoto, Takayuki Ikezoe   +7 more
wiley   +1 more source

From Data to Decisions: How Machine Learning and Generative Artificial Intelligence Are Redefining Precision Medicine in Kidney Transplantation

Organ Medicine, Volume 3, Issue 2, Page 102-118, June 2026.
This review evaluates how machine learning, multimodal integration, and generative AI optimize kidney transplant outcomes. These tools enable superior prediction and personalized therapy but face hurdles in data volume, generalizability, and ethics. Future clinical adoption depends on continued innovation and multidisciplinary collaboration to overcome
Maoxin Liao, Cheng Yang
wiley   +1 more source