Results 31 to 40 of about 129,949 (299)
Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells [PDF]
, 2019 Modern molecular medicine demands techniques to efficiently deliver molecules directly into mammalian cells. As proteins are the final mediators of most cellular pathways, efficient intracellular protein delivery techniques are highly desired.
Braeckmans, Kevin +10 more
core +2 more sources
Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells [PDF]
, 2017 Docosahexaenoic acid (DHA), a ω-3 polyunsaturated fatty acid found in fish oil, is a multi-target agent and exerts anti-inflammatory and anticancer activities alone or in combination with chemotherapies.
D'Eliseo, Donatella +3 more
core +1 more source
Radiotherapy and Immunogenic Cell Death
Seminars in Radiation Oncology, 2015 Advances in understanding the mechanisms that underlie the interplay between radiation-invoked immune responses and tumor regression are underway. Emerging applications of local radiotherapy as an immunologic adjuvant have provided radiation oncologists with a method for converting malignant cells into endogenous anticancer vaccines.
Golden, Encouse B., Apetoh, Lionel
openaire +2 more sources
Frontiers in Oncology, 2023 Immunotherapy is widely regarded as a promising treatment for cancer. However, the immune effector phase suppression of tumor microenvironment (TME) and the generation of immune-related adverse events limit its application.
Ting Wang +8 more
doaj +1 more source
Measles virus causes immunogenic cell death in human melanoma [PDF]
, 2011 Oncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma.
Bond, Jacquelyn +14 more
core +1 more source
Immunogenic chemotherapy sensitizes RAS-mutated colorectal cancers to immune checkpoint inhibitors
OncoImmunology, 2023 Recent clinical trials have compared the use of different chemotherapeutic regimens as “immune induction therapies” to sensitize cancers to immune checkpoint inhibitors (ICI).
Lucillia Bezu +2 more
doaj +1 more source
Many faces of DAMPs in cancer therapy [PDF]
, 2013 A new concept of immunogenic cell death (ICD) has recently been proposed. The immunogenic characteristics of this cell death mode are mediated mainly by molecules called ‘damage-associated molecular patterns’ (DAMPs), most of which are recognized by ...
Aaes, Tania Love +4 more
core +1 more source
Cells, 2022 Innovative strategies to re-establish the immune-mediated destruction of malignant cells is paramount to the success of anti-cancer therapy. Accumulating evidence suggests that radiotherapy and select chemotherapeutic drugs and small molecule inhibitors ...
Kellsye P. Fabian +3 more
doaj +1 more source
Effect of photosensitizers photosens, photodithazine and hypericin on glioma cells and primary neuronal cultures : a comparative analysis [PDF]
, 2019 The aim of the study was to compare the effect of photosensitizers photosens, photodithazine, and hypericin on primary brain cell cultures, and assess their toxic effect on tumor and normal nervous cells in order to choose the optimal photodynamic agent ...
Alzeibak, Rozan +6 more
core +2 more sources
Molecular characteristics of immunogenic cancer cell death [PDF]
Cell Death & Differentiation, 2007 Apoptotic cell death is initiated by a morphologically homogenous entity that was considered to be non-immunogenic and non-inflammatory in nature. However, recent advances suggest that apoptosis, under certain circumstances, can be immunogenic. In particular, some characteristics of the plasma membrane, acquired at preapoptotic stage, can cause immune ...
A, Tesniere +6 more
openaire +2 more sources