Results 51 to 60 of about 45,350 (212)

Intravenous Immunoglobulin Protects Against Severe Pandemic Influenza Infection

EBioMedicine, 2017
Influenza is a highly contagious, acute, febrile respiratory infection that can have fatal consequences particularly in individuals with chronic illnesses.
Steven Rockman, Sue Lowther, Sarina Camuglia, Kirsten Vandenberg, Shirley Taylor, Lou Fabri, Sylvia Miescher, Martin Pearse, Deborah Middleton, Stephen J. Kent, Darryl Maher   +10 more
doaj   +1 more source

Gamma-globulin Inhibits Superantigen-induced Lymphocyte Proliferation and Cytokine Production

Allergology International, 2007
Background: High-dose pooled human immunoglobulin (PHIG) treatment is sometimes effective in superantigen related inflammatory diseases, such as toxic shock syndrome and Kawasaki disease.
Kumiko Kato, Tatsuo Sakamoto, Komei Ito
doaj   +1 more source

Staphylococcus pseudintermedius Sbi paralogs inhibit complement and bind IgM, IgG Fc and Fab.

PLoS ONE, 2019
The success of staphylococci as pathogens has been attributed, in part, to their ability to evade their hosts' immune systems. Although the proteins involved in evasion have been extensively studied in staphylococci affecting humans little ...
Alaa H Sewid, M Nabil Hassan, A M Ammar, David A Bemis, Stephen A Kania   +4 more
doaj   +1 more source

Production and characterization of monoclonal antibodies anti fragment Fc of bovine IgG

Brazilian Archives of Biology and Technology, 2010
The aim of this work was to produce and characterize monoclonal antibodies anti bovine immunoglobulin G (IgG). Out of seven hybridomas, two were chosen based on the ELISA'S absorbance values and were labeled B4F11 and B3H12.
Tânia Regina Penha, Ernesto Renato Krüger, Vanete Thomaz-Soccol, Jorge Victor Bacila Agottani, Flávio Hiroshi Itano, Ludmilla Della Coletta Troiano, Josiane Brodzinski   +6 more
doaj   +1 more source

Polyclonal activation of human B lymphocytes by Fc fragments. I. Characterization of the cellular requirements for Fc fragment-mediated polyclonal antibody secretion by human peripheral blood B lymphocytes

Journal of Experimental Medicine, 1981
Fc fragments derived from human immunoglobulin were found to be capable of inducing both a proliferative and polyclonal antibody response in human peripheral blood lymphocyte cultures. The cell population proliferating in response to Fc fragments belongs
E. Morgan, W. Weigle
semanticscholar   +1 more source

Vascular endothelial growth factor trap-eye and trap technology: Aflibercept from bench to bedside

Oman Journal of Ophthalmology, 2014
Anti-vascular endothelial growth factor (VEGF) currently used to treat eye diseases have included monoclonal antibodies, antibody fragments, and an aptamer.
Ali M Al-Halafi
doaj   +1 more source

Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection

Scientific Reports, 2016
Recent successes with monoclonal antibody cocktails ZMappTM and MIL77 against Ebola virus (EBOV) infections have reignited interest in antibody-based therapeutics.
Xuexing Zheng, G. Wong, Yongkun Zhao, Hualei Wang, Shihua He, Y. Bi, Weijin Chen, Hongli Jin, W. Gai, D. Chu, Zengguo Cao, Chong Wang, Quanshui Fan, H. Chi, Yuwei Gao, Tiecheng Wang, N. Feng, Feihu Yan, Geng Huang, Ying Zheng, Nan Li, Yuetao Li, Jun Qian, Y. Zou, G. Kobinger, G. Gao, X. Qiu, Songtao Yang, X. Xia   +28 more
semanticscholar   +1 more source

Regulation of the immune response: III. The role of macrophages in the potentiation of the immune response by Fc fragments.

Journal of Immunology, 1981
The Fc fragment-induced enhancement of the anti-SRBC response was found to be dependent upon the presence of functional macrophages. Fc fragments derived from human immunoglobulin were unable to enhance either the in vivo or in vitro anti-SRBC response ...
E. Morgan, W. Weigle
semanticscholar   +1 more source

INTERACTION BETWEEN DIFFERENT MOLECULAR FORMS OF IMMUNOGLOBULIN A AND RECOMBINANT DERIVATIVES POLYPEPTIDES OF BAC RECEPTOR PROTEINS FROM GROUP B STREPTOCOCCI

Медицинская иммунология, 2014
. The article concerns interactions between immunoglobulin A and recombinant P6, P7, P8 polypeptides, designed on the basis of externally localized Bac protein of the Group B streptococci, possessing IgA-binding activity.There is a current demand for ...
A. S. Korzhueva, D. G. Ibragimova, I. A. Ustinovich, Artem A. Totolian, M. P. Samoilovich, A. N. Suvorov   +5 more
doaj   +1 more source

TFPI-2 Protects Against Gram-Negative Bacterial Infection

Frontiers in Immunology, 2018
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix.
Mohamad N. Ali, Mohamad N. Ali, Gopinath Kasetty, Malin Elvén, Saud Alyafei, Sandra Jovic, Arne Egesten, Heiko Herwald, Artur Schmidtchen, Artur Schmidtchen, Artur Schmidtchen, Praveen Papareddy, Praveen Papareddy   +12 more
doaj   +1 more source