Journal for ImmunoTherapy of Cancer, 2020 Background Recent impressive advances in cancer immunotherapy have been largely derived from cellular immunity. The role of humoral immunity in carcinogenesis has been less understood.
Hui Wang +24 more
doaj +1 more source
Nanobody mediated inhibition of attachment of F18 fimbriae expressing Escherichia coli [PDF]
, 2014 Post-weaning diarrhea and edema disease caused by F18 fimbriated E. coli are important diseases in newly weaned piglets and lead to severe production losses in farming industry.
Coddens, Annelies +6 more
core +4 more sources
IVIG regulates the survival of human but not mouse neutrophils
Scientific Reports, 2017 Intravenous immunoglobulin (IVIG) are purified IgG preparations made from the pooled plasma from thousands of healthy donors and are being tested in preclinical mouse models.
Christoph Schneider +16 more
doaj +1 more source
VH-RELATED IDIOTOPES DETECTED BY SITE-DIRECTED MUTAGENESIS [PDF]
, 1992 The function of the CD4 cell surface protein as coreceptor on T helper lymphocytes and as receptor for HIV makes this glycoprotein a prime target for an immune intervention with mAb.
Cheng, Y. H. +4 more
core +1 more source
Intravenous Immunoglobulin Protects Against Severe Pandemic Influenza Infection
EBioMedicine, 2017 Influenza is a highly contagious, acute, febrile respiratory infection that can have fatal consequences particularly in individuals with chronic illnesses.
Steven Rockman +10 more
doaj +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Gamma-globulin Inhibits Superantigen-induced Lymphocyte Proliferation and Cytokine Production
Allergology International, 2007 Background: High-dose pooled human immunoglobulin (PHIG) treatment is sometimes effective in superantigen related inflammatory diseases, such as toxic shock syndrome and Kawasaki disease.
Kumiko Kato, Tatsuo Sakamoto, Komei Ito
doaj +1 more source
Efgartigimod Combined With Steroid Treatment for HAM/TSP: A Case Report
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurological disorder with limited treatment options. We report a 54‐year‐old female with decade‐long, progressive HAM/TSP, previously refractory to rituximab, who experienced worsening spastic paraparesis and neurogenic bladder dysfunction.
Jiahui Zeng +5 more
wiley +1 more source
Approaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species [PDF]
, 2020 BACKGROUND: Flow cytometry is a powerful tool for the multiparameter analysis of leukocyte subsets on the single cell level. Recent advances have greatly increased the number of fluorochrome-labeled antibodies in flow cytometry.
Debes, Gudrun F. +2 more
core +1 more source
VNARs: An Ancient and Unique Repertoire of Molecules That Deliver Small, Soluble, Stable and High Affinity Binders of Proteins [PDF]
, 2015 Peer reviewedPublisher ...
Clem +4 more
core +3 more sources