Results 61 to 70 of about 90,091 (319)

Method for identification of condition-associated public antigen receptor sequences [PDF]

open access: yeseLife 2018;7:e33050, 2017
Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. The development of immunoglobulin receptor repertoire sequencing methods makes it possible to perform repertoire-wide disease association studies of antigen receptor sequences.
arxiv   +1 more source

In vivo secretion of the mouse immunoglobulin G Fc fragment from rat submandibular glands [PDF]

open access: greenThe Journal of Gene Medicine, 2009
AbstractBackgroundSalivary glands have been proposed as target organs for gene therapy. They secrete endogenous, as well as transgenic proteins, in a polarized manner. Transgene‐encoded regulated pathway proteins primarily follow the regulated pathway in rat salivary glands and are secreted into saliva in an exocrine manner.
Gábor Rácz   +4 more
openalex   +4 more sources

IVIG regulates the survival of human but not mouse neutrophils

open access: yesScientific Reports, 2017
Intravenous immunoglobulin (IVIG) are purified IgG preparations made from the pooled plasma from thousands of healthy donors and are being tested in preclinical mouse models.
Christoph Schneider   +16 more
doaj   +1 more source

EndoS and SpeB from Streptococcus pyogenes inhibit immunoglobulin-mediated opsonophagocytosis. [PDF]

open access: yes, 2002
The human pathogen Streptococcus pyogenes primarily infects the upper respiratory tract and skin, but occasionally it disseminates and causes severe invasive disease with high mortality. This study revealed that the activity of extracellular EndoS, which
Collin, Mattias   +5 more
core   +2 more sources

Synthesis and Reactivity of Bidentate N‐Heterocyclic Carbene‐Phosphinidene Supported Si(IV) Dicationic Complexes

open access: yesEuropean Journal of Organic Chemistry, Volume 2022, Issue 45, December 6, 2022., 2022
In this publication the utilization of bis(NHCP) ligands is expanded towards complexation of silicon precursors giving access to Si(IV) dications [2 a] and [2 b]. These complexes present the first examples of bis(NHCP)‐supported Si(IV) dications, showing expected high Lewis acidity.
Ramona Baierl   +4 more
wiley   +1 more source

Immuno-capture of biomolecules on functionalized magnetic beads: From characterization to fluorescent detection of a biomarker for Alzheimer's disease toward high performance biosensing

open access: yesTalanta Open, 2023
It is reported herein a new approach to study the orientation and density of mouse antibody grafting on magnetic beads, serving for immunoassays and biosensors with fluorescent detection of biomolecules.
Ngoc Van Thanh Nguyen   +5 more
doaj  

Intravenous Immunoglobulin Protects Against Severe Pandemic Influenza Infection

open access: yesEBioMedicine, 2017
Influenza is a highly contagious, acute, febrile respiratory infection that can have fatal consequences particularly in individuals with chronic illnesses.
Steven Rockman   +10 more
doaj   +1 more source

Enhanced diffusion and enzyme dissociation [PDF]

open access: yesJournal of the American Chemical Society 2019, 2019
The concept that catalytic enzymes can act as molecular machines transducing chemical activity into motion has conceptual and experimental support, but much of the claimed support comes from experimental conditions where the substrate concentration is higher than biologically relevant and accordingly exceeds kM, the Michaelis-Menten constant. Moreover,
arxiv   +1 more source

Ferrocene derivatives with planar chirality and their enantioseparation by liquid‐phase techniques

open access: yesELECTROPHORESIS, Volume 44, Issue 1-2, Page 158-189, January 2023., 2023
Abstract In the last decade, planar chiral ferrocenes have attracted a growing interest in several fields, particularly in asymmetric catalysis, medicinal chemistry, chiroptical spectroscopy and electrochemistry. In this frame, the access to pure or enriched enantiomers of planar chiral ferrocenes has become essential, relying on the availability of ...
Paola Peluso, Victor Mamane
wiley   +1 more source

The mosaic puzzle of the therapeutic monoclonal antibodies and antibody fragments - A modular transition from full-length immunoglobulins to antibody mimetics

open access: yesLeukemia Research Reports, 2022
The use of monoclonal antibodies represents an important and efficient diagnostic and therapeutic tool in disease management and modern science but remains limited by several factors including the uneven distribution in diseased tissues as well as ...
Sami El Khatib, Mohamed Salla
doaj  

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