Results 301 to 310 of about 235,597 (396)

Class switch recombination junctions are not affected by the absence of the immunoglobulin heavy chain E_μ enhancer. [PDF]

Cell Mol Immunol, 2019
Issaoui H, Ghazzaui N, Ferrad M, Boyer F, Denizot Y.   +4 more
europepmc   +1 more source

Expression of immunoglobulin heavy chain at a high level in the absence of a proposed immunoglobulin enhancer element in cis.

, 1984
Matthias Wabl, Peter D. Burrows
openalex   +1 more source

Structure of antibodies with shared idiotypy: the complete sequence of the heavy chain variable regions of two immunoglobulin M anti-gamma globulins.

Proceedings of the National Academy of Sciences of the United States of America, 1974
J. Capra, J. Kehoe
semanticscholar   +1 more source

Transglutaminase‐mediated cytokeratin modifications implicated in bile‐acid‐induced hepatocyte death

The FEBS Journal, EarlyView.
Cholestasis and bile‐acid exposure enhance expression and activity of protein crosslinking enzymes TG1 and TG2 in hepatocytes. Substrate proteins were identified by mass spectrometry using biotin‐labeled peptides (pepK5/pepT26) or amine donor (biotinylated pentylamine; BPA). Crosslinking‐induced aggregation and fragmentation of keratin 18 and 8 (K18/K8)
Hideki Tatsukawa, Haruka Nakagawa, Chin Mun Yee, Keiko Kuwata, Kiyotaka Hitomi   +4 more
wiley   +1 more source

Current management of non‐amyloidosis monoclonal gammopathy of renal significance: Clinical features, treatment selections, responses and renal outcomes

British Journal of Haematology, EarlyView.
Daniel Cancilla, Hanny Sawaf, Xuefei Jia, Danai Dima, Ali Mehdi, Hira Shaikh, Beth Faiman, Faiz Anwer, Sandra Mazzoni, Diana Basali, Jack Khouri, Christy Samaras, Jason Valent, Shahzad Raza, Louis Williams   +14 more
wiley   +1 more source

The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement‐dependent cytotoxicity

The FEBS Journal, EarlyView.
Multimeric IgM‐fragment crystallizable region (Fc) fragments retain the ability to bind C1q and initiate the classical complement pathway, leading to C4 activation and deposition in vitro. However, the Fc cores can also inhibit complement‐dependent cytotoxicity by competing with surface‐bound antibodies for C1q engagement.
Andrea J. Pinto, Anne Chouquet, Isabelle Bally, Véronique Rossi, Nicole M. Thielens, Chantal Dumestre‐Pérard, Renate Kunert, Christine Gaboriaud, Wai Li Ling, Jean‐Baptiste Reiser   +9 more
wiley   +1 more source

Developmental regulation of DNA cytosine methylation at the immunoglobulin heavy chain constant locus. [PDF]

PLoS Genet, 2019
Oudinet C, Braikia FZ, Dauba A, Santos JM, Khamlichi AA.   +4 more
europepmc   +1 more source

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch.

, 1989
Wesley A. Dunnick, Marcus D. Wilson, Janet Stavnezer   +2 more
openalex   +1 more source

Elevation of Immunoglobulin Free Light Chain and BAFF Levels Associated With Immune Activation Predicts Survival Rates in Chronic Liver Disease

Hepatology Research, EarlyView.
ABSTRACT Aims Elevated serum free light chain (FLC) and B‐cell activating factor (BAFF) levels have been reported to be associated with B‐cell activation and to serve as biomarkers reflecting disease severity in various diseases. However, limited investigation has been conducted in the context of chronic liver disease (CLD), and the aim of this study ...
Motoh Iwasa, Akiko Eguchi, Yasuyuki Tamai, Ryuta Shigefuku, Hideaki Tanaka, Ryo Nakagawa, Mina Tempaku, Yoshinao Kobayashi, Hayato Nakagawa   +8 more
wiley   +1 more source

First Case of Transformation of Immunoglobulin Heavy Chain Variable-Mutated Chronic Lymphocytic Leukemia Into Chronic Myeloid Leukemia. [PDF]

Ann Lab Med, 2019
Zhang X, Guo X.
europepmc   +1 more source