Results 21 to 30 of about 34,792 (276)

Diversity of immunoglobulin light chain genes in non-teleost ray-finned fish uncovers IgL subdivision into five ancient isotypes [PDF]

, 2018
The aim of this study was to fill important gaps in the evolutionary history of immunoglobulins by examining the structure and diversity of IgL genes in non-teleost ray-finned fish.
Andreyushkova, Daria A, Baranov, Konstantin O, Chikaev, Nikolai A, Gessner, Jörn, Guselnikov, Sergey V, Kulemzin, Sergey V, Makunin, Alexey I, Mechetina, Ludmila V, Najakshin, Alexander M, Schartl, Manfred, Stöck, Matthias, Taranin, Alexander V, Trifonov, Vladimir A, Warren, Wesley C, Wuertz, Sven   +14 more
core   +5 more sources

QTL affecting innate immunity in Dutch dairy cattle [PDF]

, 2018
The fibronectin-binding protein A (FnBPA) is a cell surface-associated protein of Staphylococcus aureus which mediates adherence to the host extracellular matrix and is important for bacterial virulence.
Arendonk, J.A.M., van, Bovenhuis, H., Parmentier, H.K., Ploegaert, T.C.W., Poel, J.J., van der, Schopen, G.C.B., Sell-Kubiak, E.B., Tijhaar, E.   +7 more
core   +10 more sources

The Immunoglobulins of Cold-Blooded Vertebrates [PDF]

, 2014
Peer reviewedPublisher ...
Chen, Clem, Cone, Cooper, Crouch, Deza, Grey, Hadji-Azimi, Hsu, Kokubu, Leslie, Magor, Malecek, Mansikka, Patel, Schaerlinger, Schaerlinger, Small, Steiner, Turchin, Wilson, Wu, Zapata   +22 more
core   +2 more sources

The immunopathology of human schistosomiasis-III: immunoglobulin isotype profiles and response to praziquantel

Memorias do Instituto Oswaldo Cruz, 1996
Immunoglobulin (Ig) isotype (IgG, IgG1, IgG2, IgG3, IgG4, IgM, IgD and IgE) levels were investigated, both pre- and post-treatment with praziquantel (PZQ), in 43 adults and children chronically infected with Schistosoma mansoni , by means of a two-site ...
Romelia M Ramírez, Evelia Ceballos, Belkisyolé Alarcón de Noya, Oscar Noya, Nicolás Bianco   +4 more
doaj   +1 more source

Regulation of B cell fate by chronic activity of the IgE B cell receptor. [PDF]

, 2016
IgE can trigger potent allergic responses, yet the mechanisms regulating IgE production are poorly understood. Here we reveal that IgE+ B cells are constrained by chronic activity of the IgE B cell receptor (BCR).
Allen, Christopher DC, Chen, Xiangjun, Liu, Wanli, Robinson, Marcus J, Smith, Geoffrey A, Taunton, Jack, Yang, Zhiyong   +6 more
core   +1 more source

Immunoglobulin genes and diversity: what we have learned from domestic animals

Journal of Animal Science and Biotechnology, 2012
This review focuses on the diversity of immunoglobulin (Ig) genes and Ig isotypes that are expressed in domestic animals. Four livestock species—cattle, sheep, pigs, and horses—express a full range of Ig heavy chains (IgHs), including μ, δ, γ, ϵ, and α ...
Sun Yi, Liu Zhancai, Ren Liming, Wei Zhiguo, Wang Ping, Li Ning, Zhao Yaofeng   +6 more
doaj   +1 more source

Pregnancy mediated improvement of rheumatoid arthritis

Swiss Medical Weekly, 2012
QUESTION UNDER STUDY: To investigate pregnancy related changes of rheumatoid factor (RF) isotypes and anti-citrullinated protein antibodies (ACPA) and their association with disease activity and therapy in patients with rheumatoid arthritis.
Frauke Förger, Inka Vallbracht, Klaus Helmke, Peter Matthias Villiger, Monika Ostensen   +4 more
doaj   +1 more source

Exceptionally long CDR3H are not isotype restricted in bovine immunoglobulins. [PDF]

PLoS ONE, 2013
Exceptionally long third complementarity determining regions of the heavy chain (CDR3H) were previously described as a specificity of bovine IgG and IgM immunoglobulins.
Stefanie Walther, Claus-Peter Czerny, Ulrike S Diesterbeck   +2 more
doaj   +1 more source

CCCTC-binding factor locks premature IgH germline transcription and restrains class switch recombination [PDF]

, 2017
In response to antigenic stimulation B cells undergo class switch recombination (CSR) at the immunoglobulin heavy chain (IgH) to replace the primary IgM/IgD isotypes by IgG, IgE, or IgA.
Marina-Zárate, Ester, Pérez-García, Arantxa, Ramiro, Almudena R.   +2 more
core   +3 more sources

Ku80 is required for immunoglobulin isotype switching [PDF]

The EMBO Journal, 1998
Isotype switching is the DNA recombination mechanism by which antibody genes diversify immunoglobulin effector functions. In contrast to V(D)J recombination, which is mediated by RAG1, RAG2 and DNA double-stranded break (DSB) repair proteins, little is known about the mechanism of switching.
R, Casellas, A, Nussenzweig, R, Wuerffel, R, Pelanda, A, Reichlin, H, Suh, X F, Qin, E, Besmer, A, Kenter, K, Rajewsky, M C, Nussenzweig   +10 more
openaire   +2 more sources