Nature Communications, 2020 Human memory B cells differentiate from naïve B cells and can express different immunoglobulin (Ig) isotypes resulted from class-switch recombination.
Justin B. Moroney +4 more
doaj +1 more source
Vaccines, 2021 The live genetically-engineered oral rabies virus (RABV) variant SPBN GASGAS induces long-lasting immunity in foxes and protection against challenge with an otherwise lethal dose of RABV field strains both after experimental oral and parenteral routes of
Verena te Kamp +16 more
doaj +1 more source
Serum IgG2 levels are specifically associated with whole-body insulin-mediated glucose disposal in non-diabetic offspring of type 2 diabetic individuals. a cross-sectional study [PDF]
, 2018 .Preclinical studies suggested that IgG2c isotype may specifically impair skeletal muscle insulin sensitivity in mice. In this study we investigated the association between serum levels of the four IgG subclasses and insulin sensitivity in non-diabetic
Andreozzi, F +11 more
core +2 more sources
Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing. [PDF]
, 2019 Studying immune repertoire in the context of organ transplant provides important information on how adaptive immunity may contribute and modulate graft rejection. Here we characterize the peripheral blood immune repertoire of individuals before and after
Liberto, Juliane M +5 more
core +3 more sources
Three IgH isotypes, IgM, IgA and IgY are expressed in Gentoo penguin and zebra finch. [PDF]
PLoS ONE, 2017 Previous studies on a limited number of birds suggested that the IgD-encoding gene was absent in birds. However, one of our recent studies showed that the gene was definitely expressed in the ostrich and emu.
Binyue Han +5 more
doaj +1 more source
Exploration of Immunology, 2022 Aim: As the primary response antibody with increasing use as a therapeutic immunoglobulin (Ig) format, IgM is also the largest antibody structure among the five major human isotypes. Spontaneously formed pentamers and hexamers of IgM have avidity effects
Wei-Li Ling, Samuel Ken-En Gan
doaj +1 more source
Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response [PDF]
, 2012 Background: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage.
A Hainard +44 more
core +4 more sources
PLoS ONE, 2012 We performed a genome-wide association study (GWAS) on levels of serum total protein (TP), albumin (ALB), and non-albumin protein (NAP). We analyzed SNPs on autosomal chromosomes using data from 9,103 Japanese individuals, followed by a replication study
Wael M. Osman +5 more
semanticscholar +1 more source
ІMMUNOGLOBULIN ISOTYPES AND BLOOD MONOCYTE SUBPOPULATIONS IN COVID-19 FEMALE PATIENTS WITH DIFFERENT DISEASE SEVERITY [PDF]
Biotechnologia Acta, 2022 COVID-19 disease, an acute respiratory infection caused by the SARS-CoV-2 virus, manifests itself in various severity forms - mild, moderate and severe, caused by the reactions of the patient's immune response. Aim.
K. Rebenko, B. Donskoy, L. Stamboli
doaj +1 more source
Ku70 Is Required for Late B Cell Development and Immunoglobulin Heavy Chain Class Switching [PDF]
, 1998 Immunoglobulin (Ig) heavy chain (HC) class switch recombination (CSR) is a late B cell process that involves intrachromosomal DNA rearrangement.
Alt, Frederick W. +7 more
core +2 more sources