Neonatal Immunization with a Single IL-4/Antigen Dose Induces Increased Antibody Responses after Challenge Infection with Equine Herpesvirus Type 1 (EHV-1) at Weanling Age [PDF]
Neonatal foals respond poorly to conventional vaccines. These vaccines typically target T-helper (Th) cell dependent B-cell activation. However, Th2-cell immunity is impaired in foals during the first three months of life. In contrast, neonatal basophils
Babasyan, Susanna +9 more
core +13 more sources
Potential immunological markers for diagnosis and therapeutic assessment of toxocariasis
In human toxocariasis, there are few approaches using immunological markers for diagnosis and therapeutic assessment. An immunoblot (IB) assay using excretory-secretory Toxocara canis antigen was standardized for monitoring IgG, IgE and IgA antibodies in
Guita Rubinsky-Elefant +4 more
doaj +1 more source
Nematode infections may induce immune-modulatory effects and influence host-immune responses to other pathogens. The aim of the study was to investigate whether a mixed nematode-infection influences non-specific and vaccine-induced humoral immunity ...
Gürbüz Daş +6 more
doaj +1 more source
Characterization of the Interaction between the Herpes Simplex Virus Type I Fc Receptor and Immunoglobulin G [PDF]
Herpes simplex virus type I (HSV-1) virions and HSV-1-infected cells bind to human immunoglobulin G (hIgG) via its Fc region. A complex of two surface glycoproteins encoded by HSV-1, gE and gI, is responsible for Fc binding.
Bjorkman, Pamela J. +5 more
core +1 more source
Regulated progression of B lymphocyte differentiation from cultured fetal liver. [PDF]
Lymphoid fetal liver cultures (LFLC) are long-term, nontransformed cultures of early B lymphoid lineage cells which appear developmentally blocked at the pre-B stage in vitro.
Denis, KA, Dorshkind, K, Witte, ON
core +2 more sources
Antibodies and their receptors: different potential roles in mucosal defence
Over recent years it has become increasingly apparent that mucosal antibodies are not only restricted to the IgM and IgA isotypes, but that also other isotypes and particularly IgG can be found in significant quantities at some mucosal surfaces, such as ...
Rachel eHorton, Gestur eVidarsson
doaj +1 more source
Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements
Immunoglobulin class switch recombination (CSR) plays a crucial role in adaptive immune responses through a change of the effector functions of antibodies and is triggered by T-cell-dependent as well as T-cell-independent antigens.
Audrey Dauba, Ahmed Amine Khamlichi
doaj +1 more source
Characterization of mixed lymphocyte reaction blocking antibodies (MLR-Bf) in human pregnancy
Background It is known that during normal pregnancy and after immunotherapy blocking antibodies are developed, these antibodies inhibit mixed lymphocyte reaction and are also anti-mitogenic in nature.
Agrawal Suraksha +2 more
doaj +1 more source
ObjectivesTissue transglutaminase (tTG) autoantibodies are serologic markers for celiac disease (CD). The aim was to determine the diagnostic sensitivity and specificity of different immunoglobulin isotypes against tTG. MethodsImmunoglobulin A (IgA)-tTG,
D. Agardh +3 more
semanticscholar +1 more source
Immunopathology of rabies infection in mice selected for high or low acute inflammatory reaction
Rabies is a severe and lethal disease that produces a slight inflammatory response during the infection process. We analyzed the immunopathological mechanisms that occur in the central nervous system (CNS) using mice genetically selected for maximal or ...
S. M. Achkar +5 more
doaj +1 more source

