Results 171 to 180 of about 74,618 (225)

Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits with Severe Acute Kidney Injury Successfully Managed by Clone-Directed Therapy: A Case Report.

Nephron
Maekawa S, Yamamoto S, Kosaka T, Kamido H, Arai Y, Ogawa Y, Murakami N, Teramoto Y, Yanagita M.   +8 more
europepmc   +1 more source

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Immunoglobulin Structure: Amino Terminal Sequences of Kappa Chains from Genetically Similar Mice (BALB/c)

Science, 1970
The amino terminal portion of 20 kappa chains from the highly inbred BALB/c mouse has been examined on an automatic protein sequencer. These proteins can be divided into at least nine groups (subgroups) based on sequence patterns which are so distinct that each subgroup is probably encoded by at least one germ-line gene.
L E Hood, D J Mckean, M Potter
exaly   +5 more sources

Monoclonal Antibodies Against Rat Immunoglobulin Kappa Chains

Hybridoma, 1982
Monoclonal antibodies directed against rat kappa light chains have been generated by immunizing SJL/J mice with soluble rat immunoglobulin, followed by fusion of immune spleen cells with the P3-X63-Ag8 myeloma cell line. Monoclonal antibodies from three of these hybridoma cell lines, MAR 18.5, 80.2, and 103.6, have been extensively characterized.
Lewis L. Lanier, G. A. Gutman, Dorothy E. Lewis, S. Griswold, Noel L. Warner   +4 more
semanticscholar   +3 more sources

Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions.

Science, 1993
Humanized antibodies are highly efficient as immunotherapeutic reagents and have many advantages over rodent antibodies. A mouse strain was generated by gene targeting to replace the mouse kappa light chain constant (C) region gene with the human C kappa gene.
Yong-Rui Zou, H. Gu, K. Rajewsky
semanticscholar   +3 more sources

Reference Values for Immunoglobulin Kappa and Lambda Light Chains and the Kappa/Lambda Ratio in Children's Serum

Clinical Chemistry, 1992
F Aguzzi
exaly   +2 more sources

Kappa free light chains in cerebrospinal fluid to identify patients with oligoclonal bands

European Journal of Neurology, 2018
Marie Suse, A Petersmann, Maik Pietzner   +2 more
exaly   +2 more sources

Prognostic value of free light chains lambda and kappa in early multiple sclerosis

Multiple Sclerosis Journal, 2017
Margarete M Voortman, Tatjana Stojakovic, Lukas Pirpamer   +2 more
exaly   +2 more sources

Two kappa immunoglobulin light chains are secreted by an anti-DNA hybridoma: Implications for isotypic exclusion

Molecular Immunology, 1995
Andrew L Wong, Richard H Weisbart, Donald J Zack   +2 more
exaly   +2 more sources

Kappa-Chain Deficiency

New England Journal of Medicine, 1976
Since kappa-chain deficiency is an unusual condition, we studied the clinical and laboratory findings in a patient with this deficiency. The patient had cystic fibrosis with concurrent malabsorption, diabetes mellitus and IgA deficiency. The serum levels of IgM and IgG were 0.85 and 7.22 mg per milliliter, respectively.
B J, Zegers, W J, Maertzdorf, E, Van Loghem, N A, Mul, J W, Stoop, J, Van Der Laag, J J, Vossen, R E, Ballieux   +7 more
openaire   +2 more sources

Immunoglobulin free light chains as an inflammatory biomarker of heart failure with myocarditis.

Clinical Immunology, 2020
BACKGROUND In this study, we measured immunoglobulin free light chains (FLC), a biomarker of inflammation in the sera of patients with heart failure due to myocarditis. METHODS FLC kappa and FLC lambda were assayed in stored serum samples from patients
A. Matsumori, T. Shimada, E. Nakatani, Miho Shimada, S. Tracy, N. Chapman, M. Drayson, V. Hartz, J. Mason   +8 more
semanticscholar   +1 more source