Results 231 to 240 of about 29,558 (298)

Optimized Kappa-Index Test Protocol to Detect Intrathecal Immunoglobulin Synthesis in Multiple Sclerosis. [PDF]

Eur J Neurol
Björklund J, Itkonen O, Nokelainen P, Siuko M, Österlund-Tauriala E, Tienari PJ, Anttonen M.   +6 more
europepmc   +1 more source

Decellularized Aged Bruch's Membrane Confers Unique Biochemical Cues to Retinal Pigment Epithelium for In Vitro Modeling of Age‐Related Macular Degeneration

Aging Cell, Volume 25, Issue 5, May 2026.
A Bruchs membrane (BrM) mimic based on aged decellularized BrM was developed and differentially expressed proteins in aged dECM‐BrM that may provide specific biochemical cues fundamental to model AMD in vitro were identified. RPE culture on aged dECM‐BrM developed certain AMD‐like features including reduced TEER and expression of drusen components ...
Blanca Molins, Mercedes Soledad Nabaes Jodar, Eliandre de Oliveira, Josep Maria Estanyol, Esther Peña, Jaione Bezunartea, María Hernández, Marc Figueras‐Roca, Alfredo Adan   +8 more
wiley   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, Volume 183, Issue 9, Page 1747-1778, May 2026.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

Classical complement activation in light and heavy chain deposition disease with acquired cutis laxa and bronchiolitis obliterans: a case report of monoclonal gammopathy of clinical significance. [PDF]

Front Immunol
Chen Y, Fan Y, Yang S, Cui H, Ye W, Ye W, Wen Y, Zhuang J, Wang P, Ma D, Fang K, Xia P, Chen L, Li H, Li C.   +14 more
europepmc   +1 more source

Novel Ligands for the Orphan Receptor GPR151 Modulate Morphine Action

Genes to Cells, Volume 31, Issue 3, May 2026.
The new GPR151 ligands altered the analgesic effects of morphine. ABSTRACT GPR151 is an orphan G‐protein‐coupled receptor expressed on specific neurons. Its expression has been reported to be upregulated in the dorsal root ganglia in mouse nerve injury models, suggesting a role in pain transmission.
Hijiri Yoshida, Takashi Suto, Hiroyuki Hirano, Hiroyuki Osada, Kazuto Nunomura, Bangzhong Lin, Shigeru Saito, Shigeki Takeda   +7 more
wiley   +1 more source

CNS-compartmentalized IgG aggregates and glycosylation in multiple sclerosis contribute to oligoclonal bands and neuronal cytotoxicity. [PDF]

Front Immunol
Asokan S, Zhou W, Fringuello A, Pointon T, Kennedy A, Freitas B, Tumas French J, Zhao H, Coughlan C, Alvarez E, Yu X.   +10 more
europepmc   +1 more source

Why Is MS a More Frequent Complication of EBV Infection in Females?

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn, Nuria Alvarez‐Sanchez, Lawrence Steinman   +2 more
wiley   +1 more source

Negative [99mTc]Tc -DPD Scintigraphy, Presence of Monoclonal Protein and Biopsy Suggestive of AL Amyloidosis in a Patient With Homozygous p.Ala101Val Transthyretin Gene Variant. [PDF]

Clin Case Rep
Kryszpin P, Jachimowski P, Augustowski Ł, Ziarkiewicz M, Basak G, Lipowska M, Legatowicz-Koprowska M, Ziarkiewicz-Wróblewska B, Gawor-Prokopczyk M.   +8 more
europepmc   +1 more source

IgG-type lymphoplasmacytic lymphoma with light chain deposition disease. [PDF]

CEN Case Rep
Ozeki T, Ito S, Sugiura T, Yokoe Y, Yasuda K.   +4 more
europepmc   +1 more source