Nonchemotherapy Treatment of Immunoglobulin Light Chain Amyloidosis [PDF]
Immunoglobulin light chain amyloidosis (AL amyloidosis) is a rare, life-threatening disease characterized by the deposition of misfolded proteins in vital organs such as the heart, the lungs, the kidneys, the peripheral nervous system, and the gastrointestinal tract. This causes a direct toxic effect, eventually leading to organ failure. The underlying
Layla Van Doren, Suzanne Lentzsch
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Presentation and Outcomes of Localized Immunoglobulin Light Chain Amyloidosis: 14-Year Experience of an Academic Center. [PDF]
Dima D +11 more
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Evaluation of Cytokine Levels in Cardiac Transthyretin and Immunoglobulin Light Chain Amyloidosis and Their Correlation with Myocardial Inflammatory Cells and MACE. [PDF]
Musigk N +8 more
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A mouse model of cardiac immunoglobulin light chain amyloidosis reveals insights into tissue accumulation and toxicity of amyloid fibrils. [PDF]
Martinez-Rivas G +28 more
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Novel targeted therapies for immunoglobulin light chain amyloidosis: latest updates from the 2024 ASH annual meeting. [PDF]
Bu Q, Zhu HH, Chen W.
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Modified High-Dose Melphalan and Autologous Stem Cell Transplantation for Immunoglobulin Light Chain Amyloidosis. [PDF]
Nguyen VP +9 more
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Immunoglobulin light chain amyloidosis [PDF]
SummaryImmunoglobulin light chain (AL) amyloidosis is a rare and underdiagnosed life-threatening systemic disease, primarily caused by insoluble depositions of misfolded monoclonal light chains. The monoclonal light chain paraprotein originates from a small clonal B‑cell or a clonal plasma cell population.
Hermine Agis, Maria Theresa Krauth
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Immunoglobulin light chain amyloidosis presenting as Budd-Chiari syndrome. [PDF]
Ozercan M +5 more
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Safety and efficacy of teclistamab in systemic immunoglobulin light chain amyloidosis. [PDF]
Chakraborty R +5 more
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Periorbital Purpura as a Key Diagnostic Clue in Immunoglobulin Light Chain Amyloidosis. [PDF]
Miyaue K, Isono H.
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