Results 41 to 50 of about 72,745 (302)

Immune-Replacement Therapy in the Complex Treatment of Acute Lung Injury in Patients with Severe Sepsis

Общая реаниматология, 2007
Objective: to improve the results of intensive care in patients with acute lung injury in the presence of severe sepsis. Subjects and methods. Complex intensive therapy was analyzed in 87 patients with severe sepsis and acute lung injury.
K. B. Grigoryev, S. I. Apevalov, A. E. Matyukov, L. V. Okhinko   +3 more
doaj   +1 more source

Expression of thyroglobulin on follicular dendritic cells of thyroid mucosa-associated lymphoid tissue (MALT) lymphoma [PDF]

, 2009
Reportedly, thyroid mucosa-associated lymphoid tissue (MALT) lymphoma is closely associated with Hashimoto's thyroiditis. However, it remains unknown which antigen is closely associated with thyroid MALT lymphoma.
Akagi, Tadaatsu, Kobayashi, Keita, Mannami, Tomohiko, Miyake, Takayoshi, Munemasa, Mitsuru, Sakugawa, Sumie Takase, Shinagawa, Katsuji, Tanimoto, Mitsune, Yoshino, Tadashi   +8 more
core   +1 more source

Limited Innovations After More Than 65 Years of Immunoglobulin Replacement Therapy: Potential of IgA- and IgM-Enriched Formulations to Prevent Bacterial Respiratory Tract Infections

Frontiers in Immunology, 2018
Patients with primary immunoglobulin deficiency have lower immunoglobulin levels or decreased immunoglobulin function, which makes these patients more susceptible to bacterial infection.
Jeroen D. Langereis, Jeroen D. Langereis, Michiel van der Flier, Michiel van der Flier, Michiel van der Flier, Michiel van der Flier, Marien I. de Jonge, Marien I. de Jonge   +7 more
doaj   +1 more source

Thoracic duct fistula and renal transplantation [PDF]

, 1979
Thoracic duct drainage (TDD) was established for 21-115 days in 40 kidney recipients with an average removal per patient day of 4.7 1 lymph and 1.88 billion cells. Cellular and humoral immunity were depressed. TDD and immunosuppressive drugs were started
Franks, JJ, Halgrimson, CG, Iwaki, Y, Koep, LJ, McCalmon, RT, Schröter, GP, Starzl, TE, Subryan, V, Terasaki, PI, Weil, R   +9 more
core   +2 more sources

Passive blood anaphylaxis: subcutaneous immunoglobulins are a cause of ongoing passive anaphylactic reaction

Allergy, Asthma & Clinical Immunology, 2017
Background Allergic, especially anaphylactic, reactions during immunoglobulin replacement therapy are rare, but their pathophysiology and classification remain ambiguous.
Przemyslaw Zdziarski, Andrzej Gamian, Jacek Majda, Agnieszka Korzeniowska-Kowal   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Intravenous versus subcutaneous drug administration. Which do patients prefer? A systematic review [PDF]

, 2014
BACKGROUND: Intravenous (IV) drug delivery is commonly used for its rapid administration and immediate drug effect. Most studies compare IV to subcutaneous (SC) delivery in terms of safety and efficacy, but little is known about what patients prefer.
Fallowfield, Lesley J, Harder, Helena, Jenkins, Valerie A, Stoner, Kelly L   +3 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

New insights in the use of immunoglobulins for the management of immune deficiency (PID) patients [PDF]

, 2017
Immunoglobulin replacement therapy (IRT) is standard treatment for patients with primary immunodeficiency (PID). Because most of the patients with PID will require long life-time immunoglobulin replacement therapy, the quality of the prescribed ...
Alfa Cissé, Ousmane, Bernatowska, Ewa, Jolles, Stephen, Krivan, Gergely, Lopes Granados, Eduardo, Ouaja, Rabye, Paolantonacci, Phillipe   +6 more
core  

The V_H gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus [PDF]

, 2003
In systemic lupus erythematosus (SLE) it has been hypothesized that self-reactive B cells arise from virgin B cells that express low-affinity, nonpathogenic germline V genes that are cross-reactive for self and microbial antigens, which convert to high ...
Field, M., Fraser, N.L.W., Rowley, G., Stott, D.I.   +3 more
core   +2 more sources