Results 11 to 20 of about 89,812 (215)

Development of the expressed immunoglobulin μ chain repertoire during maturation of mice B cells [PDF]

Frontiers of Agricultural Science and Engineering, 2014
In the bone marrow and spleen, the developing B cell populations undergo both negative and positive selections to shape their B cell receptor repertoire.
Jingwen LIANG,Yingfeng LUO,Yi SUN,Meng LEI,Bing ZHANG,Songnian HU,Yaofeng ZHAO
doaj   +1 more source

Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS.

PLoS ONE, 2020
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is an unexplained chronic, debilitating illness characterized by fatigue, sleep disturbances, cognitive dysfunction, orthostatic intolerance and gastrointestinal problems.
Milica Milivojevic, Xiaoyu Che, Lucinda Bateman, Aaron Cheng, Benjamin A Garcia, Mady Hornig, Manuel Huber, Nancy G Klimas, Bohyun Lee, Hyoungjoo Lee, Susan Levine, Jose G Montoya, Daniel L Peterson, Anthony L Komaroff, W Ian Lipkin   +14 more
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Computational Inference, Validation, and Analysis of 5’UTR-Leader Sequences of Alleles of Immunoglobulin Heavy Chain Variable Genes

Frontiers in Immunology, 2021
Upstream and downstream sequences of immunoglobulin genes may affect the expression of such genes. However, these sequences are rarely studied or characterized in most studies of immunoglobulin repertoires. Inference from large, rearranged immunoglobulin
Yixun Huang, Linnea Thörnqvist, Mats Ohlin   +2 more
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Clinical significance of LAIR1 (CD305) as assessed by flow cytometry in a prospective series of patients with chronic lymphocytic leukemia

Haematologica, 2014
Most patients affected by chronic lymphocytic leukemia are diagnosed by flow cytometry. Several immunophenotypic markers have been identified as significant and independent prognostic variables, especially from retrospective cohorts.
Omar Perbellini, Erika Falisi, Ilaria Giaretta, Elisa Boscaro, Elisabetta Novella, Monica Facco, Stefania Fortuna, Silvia Finotto, Eliana Amati, Francesco Maniscalco, Anna Montaldi, Alberta Alghisi, Fiorenza Aprili, Laura Bonaldi, Rossella Paolini, Maria Teresa Scupoli, Livio Trentin, Achille Ambrosetti, Gianpietro Semenzato, Giovanni Pizzolo, Francesco Rodeghiero, Carlo Visco   +21 more
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Immunoglobulin genes and diversity: what we have learned from domestic animals

Journal of Animal Science and Biotechnology, 2012
This review focuses on the diversity of immunoglobulin (Ig) genes and Ig isotypes that are expressed in domestic animals. Four livestock species—cattle, sheep, pigs, and horses—express a full range of Ig heavy chains (IgHs), including μ, δ, γ, ϵ, and α ...
Sun Yi, Liu Zhancai, Ren Liming, Wei Zhiguo, Wang Ping, Li Ning, Zhao Yaofeng   +6 more
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Determination of variable region sequences from hybridoma immunoglobulins that target Mycobacterium tuberculosis virulence factors.

PLoS ONE, 2021
Mycobacterium tuberculosis (Mtb) infects one-quarter of the world's population. Mtb and HIV coinfections enhance the comorbidity of tuberculosis (TB) and AIDS, accounting for one-third of all AIDS-associated mortalities.
Hui-Chen Chang Foreman, Andrew Frank, Timothy T Stedman   +2 more
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A novel liver-specific immunoglobulin heavy chain-like gene in a cartilaginous fish

Fish and Shellfish Immunology Reports, 2023
We identified a novel immunoglobulin (Ig) heavy chain-like gene (tsIgH) expressed in the liver of the banded houndshark Triakis scyllium by preliminary transcriptomic analysis.
Hidehiro Kondo, Haruka Kamei, Fuyuka Murotani, Reiko Nozaki, Ryosuke Yazawa, Reoto Tani, Keiichiro Koiwai, Ikuo Hirono   +7 more
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Tumor-Associated Disialylated Glycosphingolipid Antigen-Revealing Antibodies Found in Melanoma Patients' Immunoglobulin Repertoire Suggest a Two-Direction Regulation Mechanism Between Immune B Cells and the Tumor

Frontiers in Immunology, 2019
There is far less information available about the tumor infiltrating B (TIL-B) cells, than about the tumor infiltrating T cells. We focused on discovering the features and potential role of B lymphocytes in solid tumors.
Beatrix Kotlan, Szabolcs Horvath, Klara Eles, Vanda K. Plotar, Gyorgy Naszados, Katalin Czirbesz, Miri Blank, Emil Farkas, Laszlo Toth, Jozsef Tovari, Andras Szekacs, Yehuda Shoenfeld, Maria Godeny, Miklos Kasler, Miklos Kasler, Gabriella Liszkay   +15 more
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Data on the nucleotide composition of the first codons encoding the complementary determining region 3 (CDR3) in immunoglobulin heavy chains

Data in Brief, 2018
The highly variable complementary determining region 3 (CDR3) of antibodies is generated through recombination of immunoglobulin heavy chain variable (IGHV), diversity, and joining genes.
Linnea Thörnqvist, Mats Ohlin
doaj   +1 more source

Big domains are novel Ca²+-binding modules: evidences from big domains of Leptospira immunoglobulin-like (Lig) proteins. [PDF]

PLoS ONE, 2010
BackgroundMany bacterial surface exposed proteins mediate the host-pathogen interaction more effectively in the presence of Ca²+. Leptospiral immunoglobulin-like (Lig) proteins, LigA and LigB, are surface exposed proteins containing Bacterial ...
Rajeev Raman, V Rajanikanth, Raghavan U M Palaniappan, Yi-Pin Lin, Hongxuan He, Sean P McDonough, Yogendra Sharma, Yung-Fu Chang   +7 more
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