Results 31 to 40 of about 6,076,656 (241)

Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum [PDF]

, 2001
Comparisons of immunoglobulin G (IgG) subclass responses to the major polymorphic region and to a conserved region of MSP-1 in three cohorts of African villagers exposed to Plasmodium falciparum revealed that responses to Block 2 are predominantly IgG3 ...
David R. Cavanagh, Cavanagh, D R, Cavanagh, DR, Ibrahim M. Elhassan, Elhassan, I M, Jana S. McBride, Theander, TG, Kevin Marsh, McBride, JS, Elhassan, A, Hviid, L, Khalil, E A T G, Ahmed Elhassan, Thor G. Theander, Cavanagh, David, Arnot, DE, Marsh, K, David E. Arnot, E. At Tahir G. Khalil, Khalil, EA, McBride, J S, Arnot, D E, Elhassan, IM, Theander, T G, Marsh, Kevin, Lars Hviid, Dobano, C, Carlota Dobaño, Khalil, E A   +28 more
core   +1 more source

Data on the nucleotide composition of the first codons encoding the complementary determining region 3 (CDR3) in immunoglobulin heavy chains

Data in Brief, 2018
The highly variable complementary determining region 3 (CDR3) of antibodies is generated through recombination of immunoglobulin heavy chain variable (IGHV), diversity, and joining genes.
Linnea Thörnqvist, Mats Ohlin
doaj   +1 more source

Big domains are novel Ca²+-binding modules: evidences from big domains of Leptospira immunoglobulin-like (Lig) proteins. [PDF]

PLoS ONE, 2010
BackgroundMany bacterial surface exposed proteins mediate the host-pathogen interaction more effectively in the presence of Ca²+. Leptospiral immunoglobulin-like (Lig) proteins, LigA and LigB, are surface exposed proteins containing Bacterial ...
Rajeev Raman, V Rajanikanth, Raghavan U M Palaniappan, Yi-Pin Lin, Hongxuan He, Sean P McDonough, Yogendra Sharma, Yung-Fu Chang   +7 more
doaj   +1 more source

Immunodeficiency, Centromeric Region Instability, and Facial Anomalies Syndrome (ICF) in a Boy with Variable Clinical and Immunological Presentations

Iranian Journal of Allergy, Asthma and Immunology, 2021
Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome is a rare primary immunodeficiency disorder characterized by recurrent infections and low immunoglobulin levels due to variable combined immunodeficiency, and centromeric ...
Mohammad Hassan Bemanian, Saba Arshi, Mohammad Nabavi, Mohammad Vafaee-Shahi, Morteza Fallahpour, Sima Shokri, Afshin Rezaeifar, Hossein Shahzadi, Fatemeh Atashrazm   +8 more
doaj   +1 more source

Tumor-infiltrating B cell immunoglobulin variable region gene usage in invasive ductal breast carcinoma

, 2005
A major focus of tumor immunology is to reveal the potential role and capacity of immunocompetent cells found in different solid tumor tissues. The most abundant infiltrating cells (TIL), the T lymphocytes have been investigated in details concerning T ...
Toth, J., Kotlan, B., Simsa, P., Stott, D.I., Teillaud, J.L.   +4 more
core   +8 more sources

Multiple productive immunoglobulin heavy chain gene rearrangements in chronic lymphocytic leukemia are mostly derived from independent clones

Haematologica, 2014
In chronic lymphocytic leukemia, usually a monoclonal disease, multiple productive immunoglobulin heavy chain gene rearrangements are identified sporadically. Prognostication of such cases based on immunoglobulin heavy variable gene mutational status can
Karla Plevova, Hana Skuhrova Francova, Katerina Burckova, Yvona Brychtova, Michael Doubek, Sarka Pavlova, Jitka Malcikova, Jiri Mayer, Boris Tichy, Sarka Pospisilova   +9 more
doaj   +1 more source

A genome-wide association study for allergen component sensitizations identifies allergen component–specific and allergen protein group–specific associations

Journal of Allergy and Clinical Immunology: Global, 2023
Background: Allergic diseases are some of the most common diseases worldwide. Genome-wide association studies (GWASs) have been conducted to elucidate the genetic factors of allergic diseases.
Wataru Morii, PhD, Koki Kasai, BS, Takako Nakamura, MSc, Daisuke Hayashi, MD, Monami Hara, MD, Tatsuhiko Naito, MD, PhD, Kyuto Sonehara, MD, PhD, Tatsuki Fukuie, MD, PhD, Mayako Saito-Abe, MD, PhD, Limin Yang, MD, PhD, Kiwako Yamamoto-Hanada, MD, PhD, Masami Narita, MD, PhD, Kazushi Maruo, PhD, Yukinori Okada, MD, PhD, Emiko Noguchi, MD, PhD, Yukihiro Ohya, MD, PhD   +15 more
doaj   +1 more source

98% IGHV gene identity is the optimal cutoff to dichotomize the prognosis of Chinese patients with chronic lymphocytic leukemia

Cancer Medicine, 2020
Immunoglobulin heavy chain variable region (IGHV) mutational status has been an important prognostic factor for chronic lymphocytic leukemia (CLL) for decades.
Ke Shi, Qian Sun, Chun Qiao, Huayuan Zhu, Li Wang, Jiazhu Wu, Lili Wang, Jianxin Fu, Ken H. Young, Lei Fan, Yi Xia, Wei Xu, Jianyong Li   +12 more
doaj   +1 more source

HIV gp120 Induces the Release of Proinflammatory, Angiogenic, and Lymphangiogenic Factors from Human Lung Mast Cells

Vaccines, 2020
Human lung mast cells (HLMCs) express the high-affinity receptor FcεRI for IgE and are involved in chronic pulmonary diseases occurring at high frequency among HIV-infected individuals.
Giancarlo Marone, Francesca Wanda Rossi, Antonio Pecoraro, Valentina Pucino, Gjada Criscuolo, Amato de Paulis, Giuseppe Spadaro, Gianni Marone, Gilda Varricchi   +8 more
doaj   +1 more source

Preferential use of unmutated immunoglobulin heavy variable region genes in Boxer dogs with chronic lymphocytic leukemia.

PLoS ONE, 2018
Human chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease, and immunoglobulin heavy variable region (IGHV) gene mutational status is an important prognostic marker.
Emily D Rout, Robert C Burnett, Julia D Labadie, Janna A Yoshimoto, Anne C Avery   +4 more
doaj   +1 more source