Cloned pairs of variable region genes for immunoglobulin heavy chains isolated from a clone library of the entire mouse genome. [PDF]
Darrell J. Kemp+2 more
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Immunity to Plasmodium knowlesi H strain malaria in olive baboons [PDF]
Malaria disease is a major global health and economic development threat. It results in approximately 2.7 million deaths annually. There is currently no vaccine that has been licensed for use against malaria. Studies in animal models, especially non-human primates can lead to the revelation of possible immunological mechanisms that can lead to ...
arxiv
Distribution and Association of Heavy and Light Chain Variable Region Subgroups among Human IgA Immunoglobulins [PDF]
J. Donald Capra, J. Michael Kehoe
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A computational study of the statistical mechanics of antibody-antigen conformations [PDF]
We describe the representation of the chemical affinity between the antigen-combining site of the immunoglobulin molecule and the antigen molecule as the probability of the two molecules existing in a bound state. Our model is based on the identification of shape attractors in the configuration space for the joint antibody / antigen combining site ...
arxiv
Immunoglobulin Diversity: Correlation of Non-Allelic Antigenic Markers with the Basic Sequences of the Variable Region of Human Lambda Chains [PDF]
F. W. Tisdiendorf+2 more
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Positive darwinian selection observed at the variable-region genes of immunoglobulins. [PDF]
T Tanaka, M Nei
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Energetic frustrations in protein folding at residue resolution: a simulation study of homologous immunoglobulin-like \b{eta}-sandwich proteins [PDF]
Nonnative residual interactions have attracted increasing attention in recent protein folding researches. Experimental and theoretical investigations had been set out to catch nonnative contacts that might dominate key events in protein folding. However, energetic frustrations caused by nonnative inter-residue interactions are not systematically ...
arxiv
Localization of human variable and constant region immunoglobulin heavy chain genes on subtelomeric band q32 of chromosome 14 [PDF]
O. Wesley McBride+5 more
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An Investigation into Outlier Elimination and Calculation Methods in the Determination of Reference Intervals using Serum Immunoglobulin A as a Model Data Collection [PDF]
Background: Reference intervals are essential to interpret diagnostic tests, but their determination has become controversial. Methods: In this paper parametric, non-parametric and robust reference intervals with Tukey and block elimination are calculated from a dataset of over 32,000 serum immunoglobulin A (IgA) measurements.
arxiv
Unrearranged immunoglobulin variable region genes have a functional promoter [PDF]
David L. Bentley+2 more
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