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Applications of immunohistochemistry

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Immunohistochemistry (IHC) is an important application of monoclonal as well as polyclonal antibodies to determine the tissue distribution of an antigen of interest in health and disease.
Jeyapradha Duraiyan   +3 more
doaj   +4 more sources

Immunohistochemistry

open access: yesJournal of Pathology of Nepal, 2015
Immunohistochemistry (IHC) or immunocytochemistry is a method of localizing specific antigen in tissue or cells based on antigen antibody reaction. IHC is the way of validating morphological findings.
G Aryal
doaj   +6 more sources

Immunohistochemistry: Relevance in dermatology

open access: yesIndian Journal of Dermatology, 2011
Use of immunohistochemical technique is increasing in diagnosing various diseases. In many situations it may not be possible to differentiate entities with overlapping clinical and histopathological features.
Aparna Palit, Arun C Inamadar
doaj   +4 more sources

HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma

open access: yesInternational Journal of Dentistry, 2021
Background. Ameloblastoma (AMB) is a benign odontogenic tumour, with an aggressive local behaviour and a high rate of recurrence. Previous studies have demonstrated that hypoxia-induced factor alpha 1 (HIF-1α) and activated caspase-3 contribute to tumour
Katherine Julissa Palma Valladares   +10 more
doaj   +1 more source

Key proteins of invadopodia are overexpressed in oral squamous cell carcinoma suggesting an important role of MT1-MMP in the tumoral progression

open access: yesDiagnostic Pathology, 2021
Background Oral squamous cell carcinoma (OSCC) is the most relevant malignant neoplasm among all head and neck tumours due to its high prevalence and unfavourable prognosis.
Geovanni Pereira Mitre   +5 more
doaj   +1 more source

Basics of Immunohistochemistry [PDF]

open access: yesJournal of Investigative Dermatology, 2015
INTRODUCTION Immunohistochemistry (IHC) is a powerful method for localizing specific antigens in formalin-fixed, paraffin-embedded (FFPE) tissues based on antigen–antibody interaction (Taylor and Burns, 1974). The technique is widely used in dermatologic diagnostics and research, and its applications continue to be extended because of its ease of use ...
Johannes S. Kern, Vivien Schacht
openaire   +3 more sources

Expression of stem cell markers SALL4, LIN28A, and KLF4 in ameloblastoma

open access: yesDiagnostic Pathology, 2023
Background Ameloblastoma (AME) is a benign odontogenic tumour of epithelial origin characterised by slow but aggressive growth, infiltration, and recurrence; it is capable of reaching large dimensions and invading adjacent structures.
Rafaela de Albuquerque Dias   +4 more
doaj   +1 more source

Subfamily hypostominae: similarities and differences in testicular structure of amazonian fish

open access: yesBMC Zoology, 2022
Background Hypostominae is a subfamily of the family Loricariidae that has a great diversity of species. Accordingly, testicular studies in fish can contribute to the phylogeny and taxonomy of species and to the comparison of reproductive aspects between
Ivana Kerly S. Viana   +7 more
doaj   +1 more source

Analyzing the relationship between the cytokine profile of invasive breast carcinoma, its histopathological characteristics and metastasis to regional lymph nodes

open access: yesScientific Reports, 2021
This study was aimed at analyzing the relations of metastasis to regional lymph nodes (RLNs) with histopathological indicators of invasive breast carcinoma of no special type (IC-NST) and its cytokine profile.
Alexander Autenshlyus   +7 more
doaj   +1 more source

Immunoexpression of stem cell markers SOX-2, NANOG AND OCT4 in ameloblastoma [PDF]

open access: yesPeerJ, 2023
Background Ameloblastoma (AME) is characterized by a locally invasive growth pattern. In an attempt to justify the aggressiveness of neoplasms, the investigation of the role of stem cells has gained prominence.
Karolyny Martins Balbinot   +10 more
doaj   +2 more sources

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