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Immunohistochemistry

open access: yesJournal of Pathology of Nepal, 2015
Immunohistochemistry (IHC) or immunocytochemistry is a method of localizing specific antigen in tissue or cells based on antigen antibody reaction. IHC is the way of validating morphological findings.
G Aryal
doaj   +6 more sources

Applications of immunohistochemistry

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Immunohistochemistry (IHC) is an important application of monoclonal as well as polyclonal antibodies to determine the tissue distribution of an antigen of interest in health and disease.
Jeyapradha Duraiyan   +3 more
doaj   +4 more sources

Immunohistochemistry in Ophthalmology

open access: yesDelhi Journal of Ophthalmology, 2017
Immunohistochemistry is a pathological technique wherein the distribution of a particular protein or lipid antigen in a tissue specimen is determined using a combination of immunological, histochemical and biochemical principles.
Smriti Nagpal Gupta   +4 more
doaj   +4 more sources

Immunohistochemistry: Relevance in dermatology

open access: yesIndian Journal of Dermatology, 2011
Use of immunohistochemical technique is increasing in diagnosing various diseases. In many situations it may not be possible to differentiate entities with overlapping clinical and histopathological features.
Aparna Palit, Arun C Inamadar
doaj   +4 more sources

Key proteins of invadopodia are overexpressed in oral squamous cell carcinoma suggesting an important role of MT1-MMP in the tumoral progression

open access: yesDiagnostic Pathology, 2021
Background Oral squamous cell carcinoma (OSCC) is the most relevant malignant neoplasm among all head and neck tumours due to its high prevalence and unfavourable prognosis.
Geovanni Pereira Mitre   +5 more
doaj   +1 more source

HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma

open access: yesInternational Journal of Dentistry, 2021
Background. Ameloblastoma (AMB) is a benign odontogenic tumour, with an aggressive local behaviour and a high rate of recurrence. Previous studies have demonstrated that hypoxia-induced factor alpha 1 (HIF-1α) and activated caspase-3 contribute to tumour
Katherine Julissa Palma Valladares   +10 more
doaj   +1 more source

Expression of stem cell markers SALL4, LIN28A, and KLF4 in ameloblastoma

open access: yesDiagnostic Pathology, 2023
Background Ameloblastoma (AME) is a benign odontogenic tumour of epithelial origin characterised by slow but aggressive growth, infiltration, and recurrence; it is capable of reaching large dimensions and invading adjacent structures.
Rafaela de Albuquerque Dias   +4 more
doaj   +1 more source

Basics of Immunohistochemistry [PDF]

open access: yesJournal of Investigative Dermatology, 2015
INTRODUCTION Immunohistochemistry (IHC) is a powerful method for localizing specific antigens in formalin-fixed, paraffin-embedded (FFPE) tissues based on antigen–antibody interaction (Taylor and Burns, 1974). The technique is widely used in dermatologic diagnostics and research, and its applications continue to be extended because of its ease of use ...
Johannes S. Kern, Vivien Schacht
openaire   +3 more sources

p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial

open access: yesModern Pathology, 2022
Standard molecular classification of endometrial cancers (EC) is now endorsed by the WHO and identifies p53-abnormal (p53abn) EC as the subgroup with the poorest prognosis and the most likely to benefit from adjuvant chemo(radio)therapy.
L. Vermij   +37 more
semanticscholar   +1 more source

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