Results 51 to 60 of about 1,221,475 (381)

Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy. [PDF]

, 2019
BackgroundProgressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by neuronal loss in the extrapyramidal system with pathologic accumulation of tau in neurons and glia.
Dickson, Dennis W, Duara, Ranjan, Graff-Radford, Neil R, Josephs, Keith A, Litvan, Irene, Murray, Melissa E, Sakae, Nobutaka, Uitti, Ryan J, Wszolek, Zbigniew K   +8 more
core   +1 more source

Interpretation of P53 Immunohistochemistry in Endometrial Carcinomas: Toward Increased Reproducibility

International Journal of Gynecological Pathology, 2018
P53 immunohistochemistry has evolved into an accurate surrogate reflecting the underlying TP53 mutation status of a tumor, and has utility in the diagnostic workup of endometrial carcinomas.
M. Köbel, B. Ronnett, N. Singh, R. Soslow, C. Gilks, W. McCluggage   +5 more
semanticscholar   +1 more source

Follicular complex may predict reproductive tactics in siluriform fishes

Heliyon, 2023
In this study, we evaluated the morphology and morphometry of the layers that make up the follicular complex surrounding mature oocytes in the six fish species Auchenipterichthys longimanus, Ageneiosus ucayalensis, Hypophthalmus marginatus, Baryancistrus
Ivana Kerly S. Viana, Maria Auxiliadora P. Ferreira, Yanne A. Mendes, Breno Richard M. Silva, Liziane A.B. Gonçalves, Rossineide M. Rocha   +5 more
doaj  

Immunohistochemistry

Journal of Pathology of Nepal, 2015
Immunohistochemistry (IHC) or immunocytochemistry is a method of localizing specific antigen in tissue or cells based on antigen antibody reaction. IHC is the way of validating morphological findings.
G Aryal
doaj   +1 more source

Acutely damaged axons are remyelinated in multiple sclerosis and experimental models of demyelination [PDF]

, 2017
Remyelination is in the center of new therapies for the treatment of multiple sclerosis to resolve and improve disease symptoms and protect axons from further damage.
Bramlett, Brück, Brück, Clark, Cunningham, Foote, Fünfschilling, Gudi, Hiremath, Hiremath, Irvine, Irvine, Kornek, Kuhlmann, Kutzelnigg, Lassmann, Lassmann, Lee, Lindner, Lindner, Lucchinetti, Manrique-Hoyos, Mason, Matsushima, McKenzie, Mildner, Morrison, Murray, Nikic, Otsuka, Patrikios, Pierce, Schuh, Simons, Singh, Skripuletz, Sorbara, Stidworthy, Trapp   +38 more
core   +1 more source

Comparison of Immunohistochemistry for PRAME With Cytogenetic Test Results in the Evaluation of Challenging Melanocytic Tumors

American Journal of Surgical Pathology, 2020
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen. Although diffuse immunoreactivity for PRAME is found in most primary cutaneous melanomas, melanocytic nevi express PRAME usually only in a subpopulation of tumor cells
C. Lezcano, A. Jungbluth, K. Busam
semanticscholar   +1 more source

An observational study of gastrointestinal stromal tumors by histopathology and immunohistochemistry

Journal of Medical and Scientific Research, 2023
Introduction: Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms of the gastrointestinal tract and their diagnosis is mainly based on histopathology and immunohistochemical study with CD117 marker.
Kesarwani D, Kolte N, Kesarwani A, Jain S   +3 more
doaj   +1 more source

Peribiliary glands are key in regeneration of the human biliary epithelium after severe bile duct injury [PDF]

, 2019
Peribiliary glands (PBG) are a source of stem/progenitor cells organized in a cellular network encircling large bile ducts. Severe cholangiopathy with loss of luminal biliary epithelium has been proposed to activate PBG, resulting in cell proliferation ...
Carpino, Guido, de Jong, Iris E M, Gaudio, Eugenio, Gouw, Annette S H, Iswandana, Raditya, Lisman, Ton, Matton, Alix P M, Olinga, Peter, Oosterhuis, Dorenda, Overi, Diletta, Porte, Robert J, Suriguga, Su, van Haaften, Wouter T, van Praagh, Jasper B, van Wijk, Louise A, Wiersema-Buist, Janneke   +15 more
core   +3 more sources

Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry

Nature Communications, 2019
Tumor-associated macrophages (TAMs), one of the most abundant immune components in gastric cancer (GC), are difficult to characterize due to their heterogeneity.
Yu-Kuan Huang, Minyu Wang, Yu Sun, Natasha Di Costanzo, C. Mitchell, A. Achuthan, J. Hamilton, R. Busuttil, A. Boussioutas   +8 more
semanticscholar   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source