Results 81 to 90 of about 3,331 (204)

In Silico Targeting and Immunological Profiling of PpiA in Mycobacterium tuberculosis: A Computational Approach

Pathogens
Tuberculosis (TB) remains a leading cause of mortality, with drug resistance highlighting the need for new vaccine targets. Peptidyl-prolyl isomerase A (PpiA), a conserved Mycobacterium tuberculosis (Mtb) protein, plays a role in bacterial stress ...
Mohammad J. Nasiri, Lily Rogowski, Vishwanath Venketaraman   +2 more
doaj   +1 more source

From in silico Protein Epitope Density Prediction to Testing Escherichia coli O157:H7 Vaccine Candidates in a Murine Model of Colonization

Frontiers in Cellular and Infection Microbiology, 2016
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a leading cause of foodborne illnesses worldwide and is a common serotype linked to hemorrhagic colitis and an important cause of hemolytic uremic syndrome (HUS).
Daniel Tapia, Brittany N Ross, Anjana Kalita, Mridul Kalita, Christopher L Hatcher, Laura A Muruato, Alfredo G Torres   +6 more
doaj   +1 more source

Design of a Novel Multi-Epitope Vaccine Against Echinococcus granulosus in Immunoinformatics

, 2021
Mingkai Yu, Yuejie Zhu, Yujiao Li, Zhiqiang Chen, Tong Sha, Zhiwei Li, Fengbo Zhang, Jianbing Ding   +7 more
openalex   +1 more source

New Immunoinformatics Tools for Swine: Designing Epitope-Driven Vaccines, Predicting Vaccine Efficacy, and Making Vaccines on Demand [PDF]

, 2020
Leonard Moise, Andrés H. Gutiérrez, Sundos Khan, Swan Tan, Matt Ardito, William Martin, Anne S. De Groot   +6 more
openalex   +1 more source

A comprehensive strategy for the development of a multi-epitope vaccine targeting Treponema pallidum, utilizing heat shock proteins, encompassing the entire process from vaccine design to in vitro evaluation of immunogenicity

Frontiers in Microbiology
BackgroundTreponema pallidum, the causative spirochete of syphilis, is primarily transmitted through sexual contact and has emerged as a significant global health concern.
Jing Jiang, Jing Jiang, Linglan Xu, Linglan Xu, Xuefeng Wang, Ming Wang, Youde Cao, Ranhui Li, Kang Zheng, Xian Wu   +9 more
doaj   +1 more source

Epitope-Based Peptide prediction of vaccine against European bat lyssaviruses type 2 Glycoprotein G with Immunoinformatic Approach [PDF]

, 2021
Manal Abdalla Gumaa, Abeer Babiker Idris, H. Bashir, Enas dk. Dawoud, Elhassn. Lina, Mohamed A. Hassan   +5 more
openalex   +1 more source

Immunoinformatic design of a COVID-19 subunit vaccine using entire structural immunogenic epitopes of SARS-CoV-2 [PDF]

, 2020
Esmaeil Behmard, Bijan Soleymani, Ali Najafi, Ebrahim Barzegari   +3 more
openalex   +1 more source

Immunoinformatics and Pepscan strategies on the path of a peptide-based serological diagnosis of COVID19

, 2021
María Angelita Lorenzo, Diana Isabel Pachón-Suárez, Alexandra Maier, Henry Bermúdez, Sandra Losada, Marilyan Toledo, Flor H. Pujol, Belkisyolé Alarcón de Noya, Óscar Noya, María Luisa Serrano   +9 more
openalex   +2 more sources

Immunoinformatics: Implications on Reverse Vaccinology

Immunochemistry & Immunopathology, 2017
One area in which immunological studies have had most immediate and successful application is in the field of vaccination. Vaccines represent one of the greatest interventions in modern medicine [1]. Ever since Edward Jenner’s first use of a vaccine against smallpox in 1796, the use of vaccines has become indispensable to the eradication of disease [2].
openaire   +1 more source

Novel Reoviruses of Waterfowl Origin in Northern Vietnam: A Laboratory Investigation

Microbiology Research
Novel waterfowl reoviruses (nWRVs) have been reported in several countries, but their circulation and genetic characteristics in Vietnam remain poorly understood. In this study, we investigated nWRVs in northern Vietnam through molecular detection, virus
Thi-Ngoc Vu, Van-Truong Le, Thi-Bich-Phuong Cao, Van-Giap Nguyen, Thi-My-Le Huynh   +4 more
doaj   +1 more source