Lymphocyte repertoire selection and intracellular self/not-self discrimination: historical overview [PDF]
Immunological self/not-self discrimination is conventionally seen as an extracellular event, involving interactions been receptors on T cells pre-educated to discriminate, and peptides bound to major histocompatibility complex proteins (pMHCs). Mechanisms by which not-self peptides might first be sorted intracellularly to distinguish them from the vast
arxiv
A Review of Mathematical Models for Muscular Dystrophy: A Systems Biology Approach [PDF]
Muscular dystrophy (MD) describes generalized progressive muscular weakness due to the wasting of muscle fibers. The progression of the disease is affected by known immunological and mechanical factors, and possibly other unknown mechanisms. These dynamics have begun to be elucidated in the last two decades.
arxiv
A Proposed Classification of the Immunological Diseases
The formal recognition and genetic understanding of the autoinflammatory diseases has defined mechanisms of self-directed inflammation that are independent of adaptive immunity.
Michael F. McDermott, Dennis McGonagle
openaire +5 more sources
Infection severity across scales in multi-strain immuno-epidemiological Dengue model structured by host antibody level [PDF]
Infection by distinct Dengue virus serotypes and host immunity are intricately linked. In particular, certain levels of cross-reactive antibodies in the host may actually enhance infection severity leading to Dengue hemorrhagic fever (DHF). The coupled immunological and epidemiological dynamics of Dengue calls for a multi-scale modeling approach.
arxiv
Immunity to Plasmodium knowlesi H strain malaria in olive baboons [PDF]
Malaria disease is a major global health and economic development threat. It results in approximately 2.7 million deaths annually. There is currently no vaccine that has been licensed for use against malaria. Studies in animal models, especially non-human primates can lead to the revelation of possible immunological mechanisms that can lead to ...
arxiv
How sustainable environments have reduced the diffusion of coronavirus disease 2019: the interaction between spread of COVID-19 infection, polluting industrialization, wind (renewable) energy [PDF]
This study endeavors to explain the relation between air pollution and particulate compounds emissions, wind resources and energy, and the diffusion of COVID-19 infection to provide insights of sustainable policy to prevent future epidemics. The statistical analysis here focuses on case study of Italy, one of the countries to experience a rapid ...
arxiv
An Immunological Study of Coeliac Disease and Idiopathic Steatorrhoea [PDF]
K. B. Taylor+3 more
openalex +3 more sources
Maximum Matchings in Graphs for Allocating Kidney Paired Donation [PDF]
Relatives and friends of an end-stage renal disease patient who offer to donate a kidney are often found to be incompatible with their intended recipients. Kidney paired donation matches one patient and his incompatible donor with another patient and donor in the same situation for an organ exchange.
arxiv
BCG turns 100: its nontraditional uses against viruses, cancer, and immunologic diseases. [PDF]
Singh AK, Netea MG, Bishai WR.
europepmc +1 more source
Immunologically mediated oral diseases
Immune mediated diseases of oral cavity are uncommon. The lesions may be self-limiting and undergo remission spontaneously. Among the immune mediated oral lesions the most important are lichen planus, pemphigus, erythema multiformi, epidermolysis bullosa, systemic lupus erythematosis.
N Balachader+3 more
openaire +3 more sources