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Kinetoplastids:related protozoan pathogens, different diseases [PDF]

open access: yes, 2008
Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma and Leishmania, which are human pathogens with devastating health and economic effects. The sequencing of the genomes of some of these species has highlighted their
Agranoff   +127 more
core   +4 more sources

Infections Complicating Orthotopic Liver Transplantation: A Study Emphasizing Graft-Related Septicemia [PDF]

open access: yes, 1976
In 93 recipients of 102 orthotopic liver homografts, the incidence of bacteremia or fungemia exceeded 70%. The graft itself was usually an entry site for systemic infection after both immunologic and nonimmunologic parenchymal injury, especially if there
Hansbrough, JF   +5 more
core   +1 more source

Uveitis and hypereosinophilia associated with dupilumab in an atopic dermatitis patient

open access: yesJournal of Dermatological Treatment, 2023
Uveitis is a rare adverse event of dupilumab, that typically affects both eyes and often leads to discontinuation of therapy. In this article, we report a case of a 28-year-old female with atopic dermatitis who developed new-onset iridocyclitis, a form ...
Shiyu Zhang   +8 more
doaj   +1 more source

Persistent effects of early infant diet and associated microbiota on the juvenile immune system. [PDF]

open access: yes, 2015
Early infant diet has significant impacts on the gut microbiota and developing immune system. We previously showed that breast-fed and formula-fed rhesus macaques develop significantly different gut microbial communities, which in turn are associated ...
Ardeshir, Amir   +5 more
core   +1 more source

Peripheral B-Cell Immunophenotyping Identifies Heterogeneity in IgG4-Related Disease

open access: yesFrontiers in Immunology, 2021
ObjectivesTo elucidate heterogeneity of IgG4-related disease (IgG4-RD) based on B cell immunophenotyping.MethodsImmunophenotyping of 4 B-cell subsets in peripheral blood from patients with active IgG4-RD (aIgG4-RD, n=105) was performed using flow ...
Jieqiong Li   +17 more
doaj   +1 more source

On the crossroad between tolerance and posttransplant lymphoma. [PDF]

open access: yes, 1997
The role of the Epstein-Barr virus in the development of post-transplant lymphomas is well established. However, not all lymphomas that arise in these patients contain Epstein-Barr virus, suggesting that other cofactors are involved in tumor pathogenesis.
Nalesnik, Michael A, Starzl, Thomas E
core   +1 more source

Alterations of the human gut microbiome in multiple sclerosis

open access: yesNature Communications, 2016
The gut microbiome has been implicated in several autoimmune disorders. Here, the authors study the gut microbiome of patients with multiple sclerosis, and find correlations between altered abundance of certain gut microorganisms and changes in ...
Sushrut Jangi   +24 more
doaj   +1 more source

Consensus of Chinese Experts on the Diagnosis and Treatment of Type Ⅰ Interferonopathy

open access: yes罕见病研究
Type Ⅰ interferonopathy is an autoinflammatory disease that affects multiple systems, with a high disability and mortality rate. It profoundly impacts the quality of life of patients and poses a considerable burden on their families and society.
Chinese Alliance of Pediatric Rheumatic & Immunologic Diseases   +1 more
doaj   +1 more source

Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis

open access: yesNature Communications, 2017
CD4+ T cells secreting interleukin-17 (TH17) have diverse functions in modulating autoimmune diseases. Here the authors show via transcriptome analyses that a subset of human TH 17 co-expressing interferon-γ (TH1/17) has a molecular signature similar to “
Dan Hu   +19 more
doaj   +1 more source

Off-label use of abrocitinib in dermatology: A systematic literature review with narrative summary [PDF]

open access: yesJAAD International
Zheng Su, MB   +4 more
doaj   +2 more sources

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