Results 31 to 40 of about 309,789 (330)

Cell therapy in Sjögren's syndrome: opportunities and challenges

Expert Reviews in Molecular Medicine
Sjögren's syndrome (SS) is a chronic autoimmune disease caused by immune system disorders. The main clinical manifestations of SS are dry mouth and eyes caused by the destruction of exocrine glands, such as the salivary and lacrimal glands, and systemic ...
Yangyang Lu, Rongjing Shi, Wenqin He, Qi An, Jingwen Zhao, Xinnan Gao, Baiyan Zhang, Liyun Zhang, Ke Xu, Dan Ma   +9 more
doaj   +1 more source

The natural course of hereditary angioedema in a Chinese cohort

Orphanet Journal of Rare Diseases, 2020
Background Hereditary angioedema (HAE) is a rare disease with potential life-threatening risks. To study the natural course of HAE under therapy-free conditions throughout patient life is essential for practitioners and patients to avoid possible risk ...
Yang Cao, Shuang Liu, Yuxiang Zhi
doaj   +1 more source

Association of Cytomegalovirus DNA and Immunologic Markers of Cardiovascular Disease. [PDF]

, 2019
BackgroundPersons living with human immunodeficiency virus (HIV) (PLWH) with high cytomegalovirus (CMV)-specific interferon (IFN) γ response have increased numbers of endothelium homing receptor (CX3CR1)+-expressing cells that are associated with ...
Garg, Ankita, Gianella, Sara, Nakazawa, Masato, Spector, Stephen A, Trout, Rodney   +4 more
core  

Preserved cellular immunity in smoldering acute leukemia [PDF]

, 1976
"Smoldering acute leukemia", a variant of acute myelogenous leukemia, has been recognized with frequent incidence in recent years. This is chracterized by benign clinical course, poor physical findings, leukopenia and mild anemia in the ...
Toki, Hironobu
core   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source

Single-Cell Sequencing of Immune Cell Heterogeneity in IgG4-Related Disease

Frontiers in Immunology, 2022
BackgroundThe IgG4-related disease (IgG4-RD) is an immune-mediated disorder with fibrotic manifestations. However, the transcriptional profiles of immune cell subsets at single-cell level are unknown. Herein, single-cell sequencing was used to assess the
Xunyao Wu, Xunyao Wu, Yu Peng, Jieqiong Li, Panpan Zhang, Zheng Liu, Hui Lu, Linyi Peng, Jiaxin Zhou, Yunyun Fei, Xiaofeng Zeng, Yan Zhao, Wen Zhang   +12 more
doaj   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the MK2 Inhibitor ATI-450 in Healthy Subjects: A Placebo-Controlled, Randomized Phase 1 Study

Clinical Pharmacology: Advances and Applications, 2021
David Gordon,1 Edward T Hellriegel,1 Heidi Rath Hope,2 David Burt,1 Joseph B Monahan2 1Research and Development, Aclaris Therapeutics, Inc., Wayne, PA, USA; 2Research and Development, Aclaris Therapeutics, Inc., and Confluence Discovery Technologies, Inc.
Gordon D, Hellriegel ET, Hope HR, Burt D, Monahan JB   +4 more
doaj  

Mutation update of SERPING1 related to hereditary angioedema in the Chinese population

Hereditas, 2022
Background Hereditary angioedema (HAE) is a rare disease characterized by recurrent attacks of severe swellings of the skin and submucosa. More than 900 variants of the SERPING1 gene associated with HAE have been identified.
Xue Wang, Shubin Lei, Yingyang Xu, Shuang Liu, Yuxiang Zhi   +4 more
doaj   +1 more source

Clinical Characteristics and Prognoses of Patients With Systemic Lupus Erythematosus Hospitalized for Pulmonary Infections

Frontiers in Medicine, 2021
Objective: To identify factors associated with mortality in SLE patients who were hospitalized for pulmonary infections (PIs).Methods: This single-center retrospective study analyzed the characteristics and risk factors for mortality in 95 SLE patients ...
Yanli Yang, Yanli Yang, Hui Jiang, Chuhan Wang, Nan Jiang, Chanyuan Wu, Shangzhu Zhang, Wei Jiang, Jinmin Peng, Li Weng, Jiuliang Zhao, Qian Wang, Mengtao Li, Bin Du, Yan Zhao, Xiaofeng Zeng   +15 more
doaj   +1 more source