Results 31 to 40 of about 304,177 (292)
Predictors of Failure from Primary Therapy for Giardiasis in San Diego: A Single Institution Retrospective Review. [PDF]
, 2019 This study aimed to determine the presence of giardiasis among HIV patients in San Diego, the rate of failure of metronidazole treatment, and factors associated with treatment failure.
Debnath, Anjan +2 more
core +1 more source
Single-Cell Sequencing of Immune Cell Heterogeneity in IgG4-Related Disease
Frontiers in Immunology, 2022 BackgroundThe IgG4-related disease (IgG4-RD) is an immune-mediated disorder with fibrotic manifestations. However, the transcriptional profiles of immune cell subsets at single-cell level are unknown. Herein, single-cell sequencing was used to assess the
Xunyao Wu +12 more
doaj +1 more source
Mutation update of SERPING1 related to hereditary angioedema in the Chinese population
Hereditas, 2022 Background Hereditary angioedema (HAE) is a rare disease characterized by recurrent attacks of severe swellings of the skin and submucosa. More than 900 variants of the SERPING1 gene associated with HAE have been identified.
Xue Wang +4 more
doaj +1 more source
Neutrophil Extracellular Traps Promote Aberrant Macrophages Activation in Behçet’s Disease
Frontiers in Immunology, 2021 Neutrophil extracellular traps (NETs) are upregulated and promote thrombosis in Behçet’s disease (BD). However, whether NETs promote autoinflammation in BD remains unclear.
Lu Li +11 more
doaj +1 more source
Acceleration of Precision Medicine in Pediatric Rheumatic and Immunologic Diseases
Xiehe Yixue Zazhi, 2023 Rheumatic and immunologic diseases in children may involve multiple genes and interactions between genetic and environmental factors. There are no validated biomarkers that are predictive of treatment response.
MA Mingsheng, SONG Hongmei
doaj +1 more source
Cell therapy in Sjögren's syndrome: opportunities and challenges
Expert Reviews in Molecular MedicineSjögren's syndrome (SS) is a chronic autoimmune disease caused by immune system disorders. The main clinical manifestations of SS are dry mouth and eyes caused by the destruction of exocrine glands, such as the salivary and lacrimal glands, and systemic ...
Yangyang Lu +9 more
doaj +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Clinical Pharmacology: Advances and Applications, 2021 David Gordon,1 Edward T Hellriegel,1 Heidi Rath Hope,2 David Burt,1 Joseph B Monahan2 1Research and Development, Aclaris Therapeutics, Inc., Wayne, PA, USA; 2Research and Development, Aclaris Therapeutics, Inc., and Confluence Discovery Technologies, Inc.
Gordon D +4 more
doaj
Association of Cytomegalovirus DNA and Immunologic Markers of Cardiovascular Disease. [PDF]
, 2019 BackgroundPersons living with human immunodeficiency virus (HIV) (PLWH) with high cytomegalovirus (CMV)-specific interferon (IFN) γ response have increased numbers of endothelium homing receptor (CX3CR1)+-expressing cells that are associated with ...
Garg, Ankita +4 more
core
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source