Results 301 to 310 of about 52,207 (332)
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Signaling Amplification at the Immunological Synapse
2009The immunological synapse is a dynamic structure, formed between a T cell and one or more antigen-presenting cells, characterized by lipid and protein segregation, signaling compartmentalization, and bidirectional information exchange through soluble and membrane-bound transmitters.
VIOLA, ANTONELLA +2 more
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The Immunological Synapse and Rho GTPases
2005Rho GTPases are molecular switches controlling a broad range of cellular processes including lymphocyte activation. Not surprisingly, Rho GTPases are now recognized as pivotal regulators of antigen-specific T cell activation by APCs and immunological synapse formation.
M, Deckert, C, Moon, S, Le Bras
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T-Cell Activation and Immunologic Synapse
Immunologic Research, 2005The focus of my laboratory is in three areas. The first area is our long-standing interest in the mechanics of T-cell activation. In addition to our interest in protein phosphorylation mediated by T-cell receptor engagement, we have been interested in defining the function of the immunologic synapse.
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The Immunological Synapse: A Molecular Machine Controlling T Cell Activation
Science, 1999Shannon K Bromley +2 more
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Formation and function of the lytic NK-cell immunological synapse
Nature Reviews Immunology, 2008Jordan S Orange
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T-cell-antigen recognition and the immunological synapse
Nature Reviews Immunology, 2003Johannes B Huppa, Mark M Davis
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Tuning immune responses: diversity and adaptation of the immunological synapse
Nature Reviews Immunology, 2005Peter Friedl, Matthias Gunzer
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