Results 11 to 20 of about 15,033 (230)
The many facets of immunometabolism. [PDF]
PLoS BiologyImmunometabolism describes more than just metabolic shifts in immune cells. A new collection of articles shines a light on the many facets of immunometabolism, exploring the effects of molecular, cellular, and systemic metabolic mechanisms in health and ...
Joanna Clarke, Claudio Mauro
doaj +2 more sources
Obesity: An Immunometabolic Perspective [PDF]
Frontiers in Endocrinology, 2016 Obesity, characterized by chronic activation of inflammatory pathways, is a critical factor contributing to insulin resistance (IR) and type 2 diabetes (T2D).
Indrani Ray +2 more
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Immunometabolism in Tuberculosis [PDF]
Frontiers in Immunology, 2016 Immunometabolism, the study of the relationship between bioenergetic pathways and specific functions of immune cells, has recently gained increasing appreciation. In response to infection, activation of the host innate and adaptive immune cells is accompanied by a switch in the bioenergetic pathway from oxidative phosphorylation to glycolysis, a ...
Shi, Lanbo +2 more
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Targeting immunometabolism in cancer through pharmacological and lifestyle interventions. [PDF]
PLoS BiologyImmunometabolism, a fundamental biogenic process that supports the function of immune cells, is often disrupted in diseases such as cancer. Tackling metabolic dysregulation at a cellular level has therefore emerged as a focus in drug development. However,
Rachael Julia Yuenyinn Tan +4 more
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Editorial: Skeletal Muscle Immunometabolism [PDF]
Frontiers in Physiology, 2021 Skeletal muscle inflammation is triggered by multiple physiological and pathological processes. Resident immune cells such as macrophages and dendritic cells respond to the inflammatory state of skeletal muscle, and circulating immune cells can be recruited to muscle tissue (Pillon et al., 2013).
Trollet, Capucine +4 more
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Immunometabolism Modulation in Therapy [PDF]
Biomedicines, 2021 The study of cancer biology should be based around a comprehensive vision of the entire tumor ecosystem, considering the functional, bioenergetic and metabolic state of tumor cells and those of their microenvironment, and placing particular importance on immune system cells. Enhanced understanding of the molecular bases that give rise to alterations of
Ezequiel Monferrer +10 more
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Frontiers in Immunology, 2021 Immunity and metabolism are interdependent and coordinated, which are the core mechanisms for the body to maintain homeostasis. In tumor immunology research, immunometabolism has been a research hotspot and has achieved groundbreaking changes in recent ...
Yiqiu Wei +11 more
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Targeting Immunometabolism in Glioblastoma [PDF]
Frontiers in Oncology, 2021 We have only recently begun to understand how cancer metabolism affects antitumor responses and immunotherapy outcomes. Certain immunometabolic targets have been actively pursued in other tumor types, however, glioblastoma research has been slow to exploit the therapeutic vulnerabilities of immunometabolism.
Aditya A. Mohan +8 more
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Viruses, 2023 RNA viruses are known to induce a wide variety of respiratory tract illnesses, from simple colds to the latest coronavirus pandemic, causing effects on public health and the economy worldwide.
Larissa Menezes dos Reis +5 more
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Clinical & Translational Immunology, 2023 Objectives The leading cause of mortality in patients with rheumatoid arthritis is atherosclerotic cardiovascular disease (CVD). We have shown that murine arthritis impairs atherosclerotic lesion regression, because of cellular cholesterol efflux defects
Dragana Dragoljevic +16 more
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