Results 11 to 20 of about 12,525 (189)
Immunometabolism at the Heart of Cardiovascular Disease [PDF]
JACC: Basic to Translational Science, 2023 Summary: Immune cell function among the myocardium, now more than ever, is appreciated to regulate cardiac function and pathophysiology. This is the case for both innate immunity, which includes neutrophils, monocytes, dendritic cells, and macrophages ...
Matthew DeBerge, PhD +3 more
doaj +2 more sources
Immunometabolism: Molecular Mechanisms, Diseases, and Therapies 2018 [PDF]
, 2019 Immunometabolism: Molecular mechanisms, diseases, and therapies ...
José C. Rosa +14 more
core +8 more sources
Targeting immunometabolism in cancer through pharmacological and lifestyle interventions.
PLoS BiologyImmunometabolism, a fundamental biogenic process that supports the function of immune cells, is often disrupted in diseases such as cancer. Tackling metabolic dysregulation at a cellular level has therefore emerged as a focus in drug development. However,
Rachael Julia Yuenyinn Tan +4 more
doaj +2 more sources
Mitochondrial Dysfunction Accelerates Ageing. [PDF]
, 2020 We review here the seminal findings of Desdin-Mico et al. showing that T cells with dysfunctional mitochondria induce multimorbity and premature senescence, due to mitochondrial transcription factor A (TFAM).
Johannes Schroth +3 more
core +1 more source
Frontiers in Oncology, 2021 Metabolic dysregulation in the tumor microenvironment has significant impact on immune infiltration and immune responses. However, interaction between immunity and metabolism in the ovarian microenvironment requires further exploration. We constructed an
Miner Yang +3 more
doaj +1 more source
Liver biomarkers for prognosis in COVID-19
Revista Médica del Hospital General de México, 2022 The novel coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Mortality attributable to COVID-19 remains considerably high, with case fatality rates as high as 8-11%.
Salma A. Rizo-Téllez +2 more
doaj +1 more source
Immunometabolism: Molecular Mechanisms, Diseases, and Therapies 2016 [PDF]
, 2017 Immunometabolism Research Group Institute of Biomedical Sciences University of São Paulo (USP)Exercise and Immunometabolism Research Group Department of Physical Education São Paulo State University (UNESP)Cancer and Inflammation Program Center for ...
Fabio S. Lira +7 more
core +1 more source
Systems-based approaches to study immunometabolism. [PDF]
, 2022 Technical advances at the interface of biology and computation, such as single-cell RNA-sequencing (scRNA-seq), reveal new layers of complexity in cellular systems.
Purohit, Vinee +3 more
core +1 more source
Immunometabolism and Covid-19: Could Lifelong Exercise Training Have a Protective Effect?
, 2020 The world is experiencing a severe new pandemic, in which the elderly afflicted with chronic diseases are the most affected. The aging of the immune system (immunosenescence) reduces its efficacy against viral infections and increases its susceptibility ...
Luciele Guerra Minuzzi +9 more
core +1 more source
Targeting Aging: Lessons Learned From Immunometabolism and Cellular Senescence
Frontiers in Immunology, 2021 It is well known that aging is associated with dysregulated metabolism. This is seen both in terms of systemic metabolism, as well as at the cellular level with clear mitochondrial dysfunction.
Dominique E. Martin +3 more
doaj +1 more source