Results 21 to 30 of about 9,434 (203)
Loneliness: An Immunometabolic Syndrome [PDF]
International Journal of Environmental Research and Public Health, 2021 Loneliness has been defined as an agonizing encounter, experienced when the need for human intimacy is not met adequately, or when a person’s social network does not match their preference, either in number or attributes. This definition helps us realize that the cause of loneliness is not merely being alone, but rather not being in the company we ...
Homa Pourriyahi +3 more
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Liver biomarkers for prognosis in COVID-19
Revista Médica del Hospital General de México, 2022 The novel coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Mortality attributable to COVID-19 remains considerably high, with case fatality rates as high as 8-11%.
Salma A. Rizo-Téllez +2 more
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Cell Metabolism, 2015 Immunometabolism is a burgeoning field dissecting the contribution of key metabolic pathways to immune cell development, fate, and behavior. This SnapShot provides an overview of the metabolic requirements driving immune responses in lymphocytes, T and B cells, as well as macrophages.
Murray, Peter J. +2 more
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Shining a spotlight on immunometabolism [PDF]
Communications Biology, 2020 The metabolism of immune cells is a rapidly developing field with therapeutic implications. In recognition of this exciting area, our journal is welcoming submissions of primary research articles, perspectives, comments, and review articles in immunometabolism with the aim to highlight these articles in a special collection.
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ACOD1 in immunometabolism and disease [PDF]
Cellular & Molecular Immunology, 2020 Immunometabolism plays a fundamental role in health and diseases and involves multiple genes and signals. Aconitate decarboxylase 1 (ACOD1; also known as IRG1) is emerging as a regulator of immunometabolism in inflammation and infection. Upregulation of ACOD1 expression occurs in activated immune cells (e.g., macrophages and monocytes) in response to ...
Runliu, Wu +4 more
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Targeting Aging: Lessons Learned From Immunometabolism and Cellular Senescence
Frontiers in Immunology, 2021 It is well known that aging is associated with dysregulated metabolism. This is seen both in terms of systemic metabolism, as well as at the cellular level with clear mitochondrial dysfunction.
Dominique E. Martin +3 more
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Immunometabolism in the pathogenesis of vitiligo
Frontiers in Immunology, 2022 Vitiligo is a common depigmenting skin disorder characterized by the selective loss of melanocytes. Autoimmunity, genetic, environmental, and biochemical etiology have been proposed in vitiligo pathogenesis. However, the exact molecular mechanisms of vitiligo development and progression are unclear, particularly for immunometabolism.
Chen Lyu, Yonghu Sun
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The importance of methionine metabolism
eLife, 2019 T helper cells import the amino acid methionine to synthesize new proteins and to provide the methyl groups needed for the methylation of RNA and DNA that drives T cell proliferation and differentiation.
Ramon I Klein Geltink, Erika L Pearce
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Metabolic but not transcriptional regulation by PKM2 is important for natural killer cell responses
eLife, 2020 Natural Killer (NK) cells have an important role in immune responses to viruses and tumours. Integrating changes in signal transduction pathways and cellular metabolism is essential for effective NK cells responses.
Jessica F Walls +6 more
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Immunometabolism at the Heart of Cardiovascular Disease
JACC: Basic to Translational Science, 2023 Summary: Immune cell function among the myocardium, now more than ever, is appreciated to regulate cardiac function and pathophysiology. This is the case for both innate immunity, which includes neutrophils, monocytes, dendritic cells, and macrophages ...
Matthew DeBerge, PhD +3 more
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